Zobrazeno 1 - 10
of 1 106
pro vyhledávání: '"Hiroshi NAKANISHI"'
Autor:
Shuge Gui, Junjun Ni, Shinsuke Mizutani, Norihiro Shigematsu, Hiroshi Nakanishi, Haruhiko Kashiwazaki, Zhou Wu
Publikováno v:
Food Science & Nutrition, Vol 12, Iss 5, Pp 3745-3758 (2024)
Abstract Neurotoxic microglia‐provoked neuroinflammation is implicated in cognitive decline in Alzheimer's disease (AD). Supplementation with Ginkgo biloba, phosphatidylserine, Curcuma longa, and propolis is reported to improve the cognitive functi
Externí odkaz:
https://doaj.org/article/21654c31265c42199de37d4c6fcadd26
Autor:
Satoshi Yamada, Toshiya Itoh, Taro Ikegami, Atsushi Imai, Daiki Mochizuki, Hiroshi Nakanishi, Ryuji Ishikawa, Junya Kita, Yuki Nakamura, Yoshinori Takizawa, Jun Okamura, Yoshihiro Noda, Toshihide Iwashita, Takahiko Hariyama, Mikio Suzuki, Kiyoshi Misawa, Hideya Kawasaki
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Recurrent respiratory papillomatosis (RRP) has a wide range of severity. We investigate the relationship between human papillomavirus (HPV) particle production and severity of RRP. From September 2005 to June 2021, 68 RRP samples (from 29 pa
Externí odkaz:
https://doaj.org/article/fc194602de154f6399bd0dc5be1d73e4
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S462-S463 (2023)
Externí odkaz:
https://doaj.org/article/bbb0a2514427406ba11b9a788b24c227
Autor:
Erika Inoue, Shiyo Minatozaki, Sachi Shimizu, Sayaka Miyamoto, Misato Jo, Junjun Ni, Hidetoshi Tozaki-Saitoh, Kosuke Oda, Saori Nonaka, Hiroshi Nakanishi
Publikováno v:
Cells, Vol 13, Iss 3, p 283 (2024)
Cathepsin B (CatB) is thought to be essential for the induction of Porphyromonas gingivalis lipopolysaccharide (Pg LPS)-induced Alzheimer’s disease-like pathologies in mice, including interleukin-1β (IL-1β) production and cognitive decline. Howev
Externí odkaz:
https://doaj.org/article/a0e26cdddab34dde86e5e7115e5633e7
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 21, p 15613 (2023)
Papain-like cysteine proteases are composed of 11 human cysteine cathepsins, originally located in the lysosomes. They exhibit broad specificity and act as endopeptidases and/or exopeptidases. Among them, only cathepsins B, H, C, and X/Z exhibit exop
Externí odkaz:
https://doaj.org/article/4b631e907e1c4af68ea5aeda9b4f0135
Autor:
Dongshuang Wu, Kohei Kusada, Susan Meñez Aspera, Hiroshi Nakanishi, Yanna Chen, Okkyun Seo, Chulho Song, Jaemyung Kim, Satoshi Hiroi, Osami Sakata, Tomokazu Yamamoto, Syo Matsumura, Yusuke Nanba, Michihisa Koyama, Naoki Ogiwara, Shogo Kawaguchi, Yoshiki Kubota, Hiroshi Kitagawa
Publikováno v:
ACS Materials Au, Vol 2, Iss 2, Pp 110-116 (2021)
Externí odkaz:
https://doaj.org/article/acb6e39052ac4e59aadbfcd1e6e6a799
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract The effects of stem cells from human exfoliated deciduous teeth (SHED) on mechanical allodynia were examined in mice. A single intravenous injection of SHED and conditioned medium from SHED (SHED-CM) through the left external jugular vein si
Externí odkaz:
https://doaj.org/article/81169b5e56444b048baab02f84851c29
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/f8f707fbc1574188be6b21bad0533d63
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-13 (2021)
Abstract Background Cathepsin H (CatH) is a lysosomal cysteine protease with a unique aminopeptidase activity. Its expression level is increased in activated immune cells including dendritic cells, macrophages, and microglia. We have previously repor
Externí odkaz:
https://doaj.org/article/198eb5042b2d49dfb20b556e763b07f2
Autor:
Hiroshi Nakanishi, Satoshi Yamada, Junya Kita, Daichi Shinmura, Kumiko Hosokawa, Sosuke Sahara, Kiyoshi Misawa
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
Inflammasomes are large multimeric protein complexes which regulate the activation of the proinflammatory cytokines interleukins-1β and−18 and inflammatory cell death called pyroptosis. NLRP1, NLRP3, NLRC4, AIM2, and pyrin can induce the formation
Externí odkaz:
https://doaj.org/article/d5e5ef0630844c12aeb90584d8a46314