Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Hiroshi Kurosu"'
Autor:
Marina Miura, Yutaka Miura, Yoshitaka Iwazu, Hideyuki Mukai, Takahiro Sugiura, Yuji Suzuki, Masami Kato, Mayumi Kano, Daisuke Nagata, Kazuhiro Shiizaki, Hiroshi Kurosu, Makoto Kuro-o
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Hyperphosphatemia is a major risk for poor prognosis in patients with end-stage renal disease. However, the molecular mechanism behind this link remains elusive. We and others have demonstrated that serum phosphorus levels correlate positive
Externí odkaz:
https://doaj.org/article/e2060f24832b44d682eb306226d61edb
Autor:
Hideyuki Mukai, Yutaka Miura, Kazuhiko Kotani, Atsushi Kotoda, Hiroshi Kurosu, Toshiyuki Yamada, Makoto Kuro-o, Yoshitaka Iwazu
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Calciprotein particles (CPPs) are colloids composed of solid-phase calcium-phosphate and serum protein fetuin-A. CPPs form a polydispersed system with different particle size and density. CPPs with specific physical properties can induce cal
Externí odkaz:
https://doaj.org/article/666f25b9276e4875b95681cfdf8104a6
Autor:
Kimihiko Nakamura, Naohito Isoyama, Yuki Nakayama, Toshiya Hiroyoshi, Koki Fujikawa, Yutaka Miura, Hiroshi Kurosu, Hideyasu Matsuyama, Makoto Kuro-o
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract Calciprotein particles (CPPs) are circulating colloidal mineral-protein complexes containing crystalline and/or non-crystalline (amorphous) calcium-phosphate (CaPi). Serum CPP levels correlate with vascular stiffness and calcification in pat
Externí odkaz:
https://doaj.org/article/fad24fc36bbc4644b0b2010bcae78329
Autor:
Yoshitaka Hirano, Hiroshi Kurosu, Kazuhiro Shiizaki, Yoshitaka Iwazu, Shuichi Tsuruoka, Makoto Kuro‐o
Publikováno v:
FEBS Open Bio, Vol 10, Iss 5, Pp 894-903 (2020)
Excessive intake of phosphate has been known to induce renal tubular damage and interstitial inflammation, leading to acute kidney injury or chronic kidney disease in rodents and humans. However, sensitive and early biomarkers for phosphate‐induced
Externí odkaz:
https://doaj.org/article/1e698dbd05864f5fa98355eb7bd94e14
Autor:
Satoshi Kozawa, Ryosuke Ueda, Kyoji Urayama, Fumihiko Sagawa, Satsuki Endo, Kazuhiro Shiizaki, Hiroshi Kurosu, Glicia Maria de Almeida, Sharif M. Hasan, Kiyokazu Nakazato, Shinji Ozaki, Yoshinori Yamashita, Makoto Kuro-o, Thomas N. Sato
Publikováno v:
iScience, Vol 2, Iss , Pp 238-268 (2018)
Summary: Virtually all diseases affect multiple organs. However, our knowledge of the body-wide effects remains limited. Here, we report the body-wide transcriptome landscape across 13–23 organs of mouse models of myocardial infarction, diabetes, k
Externí odkaz:
https://doaj.org/article/40d692930b7c4ec6be5e8d98e5c5efff
Autor:
Yutaka Miura, Yoshitaka Iwazu, Kazuhiro Shiizaki, Tetsu Akimoto, Kazuhiko Kotani, Masahiko Kurabayashi, Hiroshi Kurosu, Makoto Kuro-o
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-16 (2018)
Abstract Calciprotein particles (CPP) are solid-phase calcium-phosphate bound to serum protein fetuin-A and dispersed as colloids in the blood. Recent clinical studies indicated that serum CPP levels were increased with decline of renal function and
Externí odkaz:
https://doaj.org/article/3a2096288f364f7893e361803aa224a3
Publikováno v:
Key Engineering Materials. 904:480-484
This study dealt with the rotary draw bending method most used for tube bending and investigates how applied bending such as normal bending, using mandrels or pressing with booster have an effect on machining accuracy, focusing on dimensional defects
Autor:
Ariunaa Sampilvanjil, Tadayoshi Karasawa, Hiroshi Kurosu, Yasuchika Takeishi, Masafumi Takahashi, Kenji Tago, Naoya Yamada, Yutaka Miura, Kenta Fujimura, Makoto Kuro-o, Chintogtokh Baatarjav, Takanori Komada, Fumiya Anzai, Takayoshi Matsumura
Publikováno v:
ImmunoHorizons. 5:602-614
Calciprotein particles (CPPs) are nanoparticles composed of calcium phosphate crystals and fetuin-A and have been implicated in diseases associated with inflammation. In the current study, we investigated the molecular mechanisms underlying CPP-induc
Autor:
Makoto Kuro-o, Kazuhiro Shiizaki, Yutaka Miura, Masaki Kojima, Kenichi Akiyama, Yoshitaka Matsumura, Ken Tsuchiya, Hiroshi Kurosu, Asuka Sakata, Kosaku Nitta, Hirosaka Hayashi
Publikováno v:
Kidney International. 97:702-712
Fibroblast growth factor-23 (FGF23) is a hormone indispensable for maintaining phosphate homeostasis. In response to phosphate intake, FGF23 is secreted from osteocytes/osteoblasts and acts on the kidney to increase urinary phosphate excretion. Howev
Autor:
Makoto Kuro-o, Kazuhiro Shiizaki, Yoshitaka Iwazu, Yoshitaka Hirano, Hiroshi Kurosu, Shuichi Tsuruoka
Publikováno v:
FEBS Open Bio
FEBS Open Bio, Vol 10, Iss 5, Pp 894-903 (2020)
FEBS Open Bio, Vol 10, Iss 5, Pp 894-903 (2020)
Excessive intake of phosphate has been known to induce renal tubular damage and interstitial inflammation, leading to acute kidney injury or chronic kidney disease in rodents and humans. However, sensitive and early biomarkers for phosphate‐induced