Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Hiroshi Kuniishi"'
Autor:
Yoshitaka Kawashima, Misa Yamada, Hiroki Furuie, Hiroshi Kuniishi, Kie Akagi, Tomoko Kawashima, Takamasa Noda, Mitsuhiko Yamada
Publikováno v:
Neuropsychopharmacology Reports, Vol 43, Iss 3, Pp 320-327 (2023)
Abstract Aim Previous behavioral pharmacology studies involving rodents suggested riluzole had potential to be an ideal psychotropic drug for psychiatric disorders with anxiety or fear as primary symptoms. Several clinical studies have recently been
Externí odkaz:
https://doaj.org/article/d1c3f6c73ae448e78c2afc8307b074f4
Autor:
Kei Hori, Kunihiko Yamashiro, Taku Nagai, Wei Shan, Saki F. Egusa, Kazumi Shimaoka, Hiroshi Kuniishi, Masayuki Sekiguchi, Yasuhiro Go, Shoji Tatsumoto, Mitsuyo Yamada, Reika Shiraishi, Kouta Kanno, Satoshi Miyashita, Asami Sakamoto, Manabu Abe, Kenji Sakimura, Masaki Sone, Kazuhiro Sohya, Hiroshi Kunugi, Keiji Wada, Mitsuhiko Yamada, Kiyofumi Yamada, Mikio Hoshino
Publikováno v:
iScience, Vol 23, Iss 6, Pp 101183- (2020)
Summary: Impairments in synapse development are thought to cause numerous psychiatric disorders. Autism susceptibility candidate 2 (AUTS2) gene has been associated with various psychiatric disorders, such as autism and intellectual disabilities. Alth
Externí odkaz:
https://doaj.org/article/549c93a6eb7d439aace1a24299f58f6e
Autor:
Hiroshi, Kuniishi, Mitsuhiko, Yamada
Publikováno v:
Folia Pharmacologica Japonica. 158:47-50
Because the early-life period is a critical window for the development and reorganization of neural circuits, the early life environment has a great impact on cognitive and emotional functions. It has been reported that a history of early life advers
Publikováno v:
Neuropsychopharmacology. 47:1597-1607
Early-life social isolation is associated with social and emotional problems in adulthood. However, neural mechanisms underlying how social deprivation impairs social and emotional development are poorly understood. Recently, the orbitofrontal cortex
Autor:
Misa Yamada, Masatoshi Ukezono, Hiroshi Kuniishi, Kazumi Yoshizawa, Yuko Nakatake, Mitsuhiko Yamada, Hiroki Furuie
Publikováno v:
Neuroscience Research. 158:56-63
In this study, we investigated the effects of emotional stress and physical stress using the social defeat stress (SDS) model in mice. Male C57BL/6 J mice were attacked by male non-retired ICR mice for 10 min daily for 10 days (physical stress; PS),
Autor:
Bei Cheng, Moeka Koshima, Makoto Sanbo, Yasuhiro Kazuki, Hiroshi Kuniishi, Yuji Nakayama, Mitsuo Oshimura, Feng J. Gao, Satoko Matsukura, Yuich Iida, Naoyo Kajitani, Joan T. Richtsmeier, Kanako Kazuki, Roger H. Reeves, Sachiko Miyagawa-Tomita, Masumi Hirabayashi, Hiromasa Hara, Anna J. Moyer, Satoshi Ichisaka, Miho Yamakawa, Haruka Takayama, Yoshio Hata, Yicong Li, Naohiro Noda, Masaharu Hiratsuka, Shoko Takehara, Nandini Singh, Satoshi Abe
Progress in earlier detection and symptom management has increased life expectancy and quality of life in people with Down syndrome (DS). However, no drug has been approved to help individuals with DS live independently and fully. Although rat models
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::945f357459691b5818f7e80c648e75b9
https://doi.org/10.1101/2021.10.03.462958
https://doi.org/10.1101/2021.10.03.462958
Autor:
Yasumasa Hashimoto, Hiroshi Kuniishi, Kazuhisa Sakai, Yuta Fukushima, Xuan Du, Kunihiko Yamashiro, Kei Hori, Michihiro Imamura, Mikio Hoshino, Mitsuhiko Yamada, Toshiyuki Araki, Hiroyuki Sakagami, Shin’ichi Takeda, Keiji Itaka, Noritaka Ichinohe, Francesco Muntoni, Masayuki Sekiguchi, Yoshitsugu Aoki
Publikováno v:
Progress in Neurobiology. 216:102288
Duchenne muscular dystrophy (DMD) is a muscle disorder caused by DMD mutations and is characterized by neurobehavioural comorbidities due to dystrophin deficiency in the brain. The lack of Dp140, a dystrophin short isoform, is clinically associated w
Publikováno v:
Nihon yakurigaku zasshi. Folia pharmacologica Japonica. 156(2)
Exposure to stress induces alterations in synaptic functions, and increases the risk of stress-related psychiatric disorders, such as major depression and PTSD. To develop new treatments for stress-related psychiatric disorders, it is important to un
Autor:
Masayuki Sekiguchi, Yuko Nakatake, Okito Hashimoto, Keiji Wada, Hiroshi Kuniishi, Mitsuhiko Yamada
Publikováno v:
Brain, behavior, and immunity. 90
Allergic dermatitis (AD), associated with pruritus and itchiness, is one of the major stressful conditions early in life. AD also influences the incidence of neuropsychiatric disorders and developmental disorders through neuro-immune interactions. To
Autor:
Reika Shiraishi, Shoji Tatsumoto, Kazumi Shimaoka, Saki F. Egusa, Taku Nagai, Masaki Sone, Manabu Abe, Wei Shan, Kazuhiro Sohya, Kunihiko Yamashiro, Satoshi Miyashita, Hiroshi Kunugi, Yasuhiro Go, Mitsuyo Yamada, Hiroshi Kuniishi, Mikio Hoshino, Masayuki Sekiguchi, Kenji Sakimura, Asami Sakamoto, Keiji Wada, Mitsuhiko Yamada, Kouta Kanno, Kiyofumi Yamada, Kei Hori
Publikováno v:
iScience, Vol 23, Iss 6, Pp 101183-(2020)
iScience
iScience
Summary Impairments in synapse development are thought to cause numerous psychiatric disorders. Autism susceptibility candidate 2 (AUTS2) gene has been associated with various psychiatric disorders, such as autism and intellectual disabilities. Altho