Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Hiroshi Kumimoto"'
Autor:
Kanji Ishizaki, Yasuhisa Hasegawa, Keitaro Matsuo, Masayuki Shinoda, Minoru Ueda, Tomotaka Sugimura, Hiroki Furue, Takeshi Suzuki, Iwai Tohnai, Hiroshi Kumimoto, Kazuo Tajima, Kenji Mitsudo
Publikováno v:
International Journal of Cancer. 123:181-186
It was reported that there are 2 haplotypes in natural killer complex (NKC) region. One of them could be divided by NKG2D polymorphism into 2 haplotype alleles (high and low natural killer (NK) cell activity) and were associated with overall cancer r
Autor:
Kanji Ishizaki, Chikako Nishigori, Makoto Kunisada, Kunihiko Sakumi, Yusaku Nakabeppu, Hiroshi Kumimoto
Publikováno v:
Journal of Investigative Dermatology. 127(12):2865-2871
Phototherapy with narrow-band UVB (NB-UVB), with a peak exclusively at 311 nm wavelength, has been found to be more effective in treating a variety of skin diseases than conventional broad-band UVB (BB-UVB). To assess the difference in carcinogenic a
Autor:
Kanji Ishizaki, Tomotaka Sugimura, Shinichi Tsurusako, Minoru Ueda, Hiroshi Kumimoto, Kenji Mitsudo, Keitaro Matsuo, Kazuo Tajima, Takafumi Fukui, Iwai Tohnai
Publikováno v:
Journal of Oral Pathology and Medicine. 35:11-18
Biomarkers of individual susceptibility: field studiesBiomarker (including alleles if genetic): CYP1A1 exon 7 (Ile462Val, A/G), CYP2E1 5Ά- (UTR; RsaI site), intron 6 (DraI site), XPA 5Ά-UTR (A23G) and XPG exon 15 (Asp1104His, C/G)Effect studied (ph
Autor:
Yoshihiro Yamane, Hiroko Fukami, Kanji Ishizaki, Masayuki Shinoda, Shunzo Hatooka, Hiroshi Kumimoto, Yoshio Nishimoto
Publikováno v:
International Journal of Cancer. 108:228-231
Recent studies of various cancers, such as those of the breast, head and neck, bladder and lung, reported that 46-64% of somatic mutations in the D-loop region of mitochondrial DNA (mtDNA) are observed. However, in esophageal cancer, only a low rate
Autor:
Yoshio Nishimoto, Hiroshi Kumimoto, Keitaro Matsuo, Masayuki Shinoda, Nobuyuki Hamajima, Kanji Ishizaki, Shunzo Hatooka
Publikováno v:
Japanese Journal of Cancer Research : Gann
We have shown that L‐myc genotype is associated with the risk of esophageal cancer from smoking and heavy drinking. In this study, we have analyzed the relationship between the L‐myc genotypes and lung cancer risk from smoking in 191 Japanese lun
Autor:
Masayuki Shinoda, Hideki Harada, Yoshio Nishimoto, Kimiko Nishizawa, Nobuyuki Hamajima, Shunzo Hatooka, Hiroshi Kumimoto, Keitaro Matsuo, Kanji Ishizaki
Publikováno v:
Japanese Journal of Cancer Research : Gann
To understand the relationship between the L‐myc genotypes and esophageal cancer risk, a polynierase chain reaction‐based restriction fragment length polymorphism analysis was performed on 91 Japanese patients with esophageal cancer and 241 non
Autor:
Kimiko Nishizawa, Hiroshi Kumimoto, Hideki Harada, Nobuhiro Uchida, Sachiko Tokumasu, Yutaka Shimada, Kanji Ishizaki
Publikováno v:
International Journal of Cancer. 91:687-691
Using in vitro mismatch repair (MMR) assay, we have identified 3 of 22 esophageal cancer cell lines exhibiting reduced MMR activity. By means of gel-shift assay, decreased binding ability to GT mismatch and CA loop was observed in these 3 cell lines.
Publikováno v:
Nucleic Acids Research. 22:41-46
dutA is a gene specifically expressed during the development of Dictyostelium discoideum. Toward understanding its possible role in development, we isolated and characterized the gene and its complete cDNA. We found that dutA is encoded by the nuclea
Autor:
Kanji Ishizaki, Tomoyuki Kato, Kazuo Tajima, Yukihide Kanemitsu, Hiroki Furue, Takeshi Suzuki, Akio Hiraki, Keitaro Matsuo, Koji Komori, Hiroshi Kumimoto, Yasushi Yatabe, Takashi Hirai, Minoru Ueda
Publikováno v:
Carcinogenesis. 29(2)
BACKGROUND: NKG2D is an immune receptor on natural killer (NK) and other cells active in the immune system. It recognizes ligands expressed on mainly transformed cells and plays a role in their elimination through the so-called 'cancer immune surveil
Autor:
Hidemi Ito, Katashi Okuma, Kenji Wakai, Keitaro Matsuo, Hiroshi Kumimoto, Toshiko Saito, Nobuyuki Hamajima, Kazuo Tajima
Publikováno v:
Preventive medicine. 42(2)
Background. To evaluate whether feedback of genetic information regarding an L-myc polymorphism, identified as impacting on tobacco-related cancer risk, has an influence on smoking cessation, an intervention study was conducted. Methods. We recruited