Výsledky vyhledávání - "Hiroshi Kokubun"

Effects of Intraoperative Opioid Administration on Postoperative Pain and Pain Threshold: A Randomized Controlled Study

Autor: Ryoko Kawanaka, Shoko Sakuma, Hiroshi Kokubun, Shuhei Tetsu, Yugo Tagaito, Toshio Igarashi, Shan-Guang Liang, Tomohiko Aoe

Publikováno v: Journal of Clinical Medicine; Volume 11; Issue 19; Pages: 5587

Fentanyl and short-acting remifentanil are often used in combination. We evaluated the effect of intraoperative opioid administration on postoperative pain and pain thresholds when the two drugs were used. Patients who underwent gynecological laparos

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f605db4eb91951756352520354bc350

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Akademický článek

Conflicting Actions of Inhalational Anesthetics, Neurotoxicity and Neuroprotection, Mediated by the Unfolded Protein Response.

Autor: Hiroshi Kokubun¹ hiro_kokubun127@yahoo.co.jp, Hisayo Jin¹ jinhy@chiba-u.jp, Mari Komita² mari29@kj9.so-net.ne.jp, Tomohiko Aoe³ tomohikoA@med.teikyo-u.ac.jp

Publikováno v: International Journal of Molecular Sciences. 1/15/2020, Vol. 21 Issue 2, p1-14. 14p. 1 Diagram, 3 Graphs.

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Pharmacological Chaperones Attenuate the Development of Opioid Tolerance

Autor: Hisayo Jin, Hiroshi Kokubun, Tomohiko Aoe, Youta Okuyama

Publikováno v: International Journal of Molecular Sciences, Vol 21, Iss 7536, p 7536 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 20

Opioids are potent analgesics widely used to control acute and chronic pain, but long-term use induces tolerance that reduces their effectiveness. Opioids such as morphine bind to mu opioid receptors (MORs), and several downstream signaling pathways

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c21a5ea3f0a01cc731584ba1f92d593d
https://www.mdpi.com/1422-0067/21/20/7536

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Conflicting Actions of Inhalational Anesthetics, Neurotoxicity and Neuroprotection, Mediated by the Unfolded Protein Response

Autor: Mari Komita, Tomohiko Aoe, Hiroshi Kokubun, Hisayo Jin

Publikováno v: International Journal of Molecular Sciences
Volume 21
Issue 2
International Journal of Molecular Sciences, Vol 21, Iss 2, p 450 (2020)

Preclinical studies have shown that exposure of the developing brain to inhalational anesthetics can cause neurotoxicity. However, other studies have claimed that anesthetics can exert neuroprotective effects. We investigated the mechanisms associate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90c192cd2ece15de23b81b178b0165ef
https://doi.org/10.3390/ijms21020450

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Formation of SiC thin films by chemical vapor deposition with vinylsilane precursor

Autor: Takuma Doi, Shigeaki Zaima, Osamu Nakatsuka, Shigeo Yasuhara, Yong Jin, Hiroshi Kokubun, Wakana Takeuchi

Publikováno v: Japanese Journal of Applied Physics. 57:01AE08

We have examined the formation of SiC thin films by chemical vapor deposition (CVD) using vinylsilane and investigated the chemical bonding state and crystallinity of the prepared SiC thin films. We achieved the formation of a Si–H–less SiC film

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::76771c155598759c3879cd97cba80f92
https://doi.org/10.7567/jjap.57.01ae08

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Preparation of Bi-layered ferroelectric thin film by thernal MOCVD

Autor: Kazuo Shinozaki, Hiroshi Funakubo, Hideaki Machida, Norimasa Nukaga, Nobuysau Mizutani, Hiroshi Kokubun, Katsuyuki Ishikawa

Publikováno v: Ferroelectrics. 232:123-128

SrBi2Ta2O9 thin films were prepared by metalorganic chemical vapor deposition(MOCVD) from Bi(CH3)3 – Sr[Ta(O. C2H5)6]2,-O2 system. Bi(CH3)3 is liquid and take a higher vapor pressure and gas concentration stability than conventionally used Bi sourc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::14814da02d287e08fcd65f6beced1fba
https://doi.org/10.1080/00150199908015781

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Preferential solvation studied by the fluorescence lifetime of acridine in water–alcohol mixtures

Autor: Osamu Ito, Yuko Yoshikawa, Eiko Ito, Hiroshi Kokubun, Akira Watanabe

Publikováno v: J. Chem. Soc., Faraday Trans.. 92:227-230

Fluorescence lifetimes (τF) of acridine have been measured in water–alcohol solvent mixtures at room temperature. The τF of acridine in pure water (11.5 ± 0.1 ns) was drastically decreased upon the addition of small amounts of alcohol; i.e.τF=

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6d0023f643a8ae0919a148b8fd4fedb7
https://doi.org/10.1039/ft9969200227

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Dependence of the Dynamic Behavior of Supersaturated Silicic Acid on the Surface Area of the Solid Phase

Autor: Yuichi Niibori, Hiroshi Kokubun, Kazuki Iijima, Hitoshi Mimura, Yasunori Kasuga

Publikováno v: Materials Research Society Symposium Proceedings.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::153c46acabedcacb58d61ddc14aba47a
https://doi.org/10.1557/proc-1124-q10-07

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Deactivation mechanism of photoexcited 9-phenylacridine in methanol

Autor: Koichi Kikuchi, Yukari. Hattori, Chika. Sato, Hiroshi Kokubun

Publikováno v: The Journal of Physical Chemistry. 94:4039-4042

Electronic deactivation processes of excited 9-phenylacridine (9-PA) have been investigated in methanol where photoreduction occurs under UV irradiation. The fluorescence lifetime τ F and yield Φ F increase with decreasing temperature, whereas the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::16eb5c2b52145f2f33bd86c26258b663
https://doi.org/10.1021/j100373a029

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