Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Hiroshi Kito"'
Autor:
Tomoyuki Kazuta, Ayuka Murakami, Seiya Noda, Satoko Hirano, Hiroshi Kito, Koyo Tsujikawa, Hirotaka Nakanishi, Seigo Kimura, Kentaro Sahashi, Haruki Koike, Masahisa Katsuno
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 11, Iss 2, Pp 508-519 (2024)
Abstract Background and Objective Chronic graft versus host disease (GVHD)‐associated myositis targeting skeletal muscle is a relatively rare but potentially debilitating complication following allogeneic hematopoietic stem cell transplantation (HS
Externí odkaz:
https://doaj.org/article/32a56cbee4014ba8a83ba652c36a7fe6
Autor:
Silvio Boero, Julia Vodopiutz, Mohamad Maghnie, Josep M. de Bergua, Ignacio Ginebreda, Hiroshi Kitoh, Micha Langendörfer, Antonio Leiva-Gea, Jason Malone, Philip McClure, Gabriel T. Mindler, Dmitry Popkov, Robert Rodl, Pablo Rosselli, Fabio Verdoni, Viktor Vilenskii, Aaron J. Huser
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 19, Iss 1, Pp 1-15 (2024)
Abstract Background Achondroplasia is the most common form of skeletal disorder with disproportionate short stature. Vosoritide is the first disease-specific, precision pharmacotherapy to increase growth velocity in children with achondroplasia. Limb
Externí odkaz:
https://doaj.org/article/3018a155bca34461815964d4e16d6c29
Publikováno v:
Alzheimer's & Dementia. 15:P1363-P1364
Autor:
Itaru Kawashima, Masaki Matsushita, Kenichi Mishima, Yasunari Kamiya, Yusuke Osawa, Bisei Ohkawara, Kinji Ohno, Hiroshi Kitoh, Shiro Imagama
Publikováno v:
BMC Musculoskeletal Disorders, Vol 24, Iss 1, Pp 1-10 (2023)
Abstract Background Postmenopausal osteoporosis is a widespread health concern due to its prevalence among older adults and an associated high risk of fracture. The downregulation of bone regeneration delays fracture healing. Activated fibroblast gro
Externí odkaz:
https://doaj.org/article/5799846324ae40b599c9115aa3054e4e
Autor:
Kenichi Mishima, Yuka Tsukagoshi Okabe, Masaaki Mizuno, Kinji Ohno, Hiroshi Kitoh, Shiro Imagama
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract The proton pump inhibitor lansoprazole has been previously identified to upregulate the expression and transcriptional activity of runt-related transcription factor 2 (Runx2) that promotes lineage commitment and differentiation of osteoproge
Externí odkaz:
https://doaj.org/article/24926c8eb6d540858f0466cbaa2f2998
Autor:
Hiroshi Kitoh, Masako Izawa, Hiroshi Kaneko, Akiko Kitamura, Saori Matsuyama, Kohji Kato, Tomoo Ogi
Publikováno v:
Bone Reports, Vol 17, Iss , Pp 101626- (2022)
Hypophosphatasia (HPP), a genetic disorder characterized by decreased tissue-nonspecific alkaline phosphatase (TNSALP) activity, is caused by loss-of-function mutations in the ALPL gene, which encodes TNSALP. The most frequent pathogenic variant in J
Externí odkaz:
https://doaj.org/article/f78e672c32c642a5a0fb2b749ea16077
Autor:
Kenichi Mishima, Atsushi Fujita, Seiji Mizuno, Masaki Matsushita, Tadashi Nagata, Yasunari Kamiya, Noriko Miyake, Naomichi Matsumoto, Shiro Imagama, Hiroshi Kitoh
Publikováno v:
Clinical Case Reports, Vol 8, Iss 12, Pp 3109-3114 (2020)
Abstract This article reports a girl with Bardet‐Biedl syndrome (BBS) having a novel causative mutation who developed Legg‐Calvé‐Perthes disease (LCPD). There exists a possibility that the prognosis of LCPD had been adversely affected by the c
Externí odkaz:
https://doaj.org/article/c903355b8ee74bb685bdffe65ba9f109
Autor:
Hideki, Warashina, Sinji, Sakano, Sinji, Kitamura, Ken-ichi, Yamauchi, Hiroshi, Kito, Yukiharu, Hasegawa
Publikováno v:
Nagoya journal of medical science. 65(3-4)
Angel-shaped phalango-epiphyseal dysplasia is characterized by the angel shape of the middle phalanx and severe coxarthrosis in adult life. This osteochondrodysplasia shows a further variety of heterogeneous multiple epiphyseal dysplasias. It also sh
Autor:
Genta Takemoto, Masaki Matsushita, Takaaki Okamoto, Toshinari Ito, Yuki Matsuura, Chieko Takashima, Toyofumi Fengshi Chen-Yoshikawa, Hiromichi Ebi, Shiro Imagama, Hiroshi Kitoh, Kinji Ohno, Yasuyuki Hosono
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2022)
Meclozine has been developed as an inhibitor of fibroblast growth factor receptor 3 (FGFR3) to treat achondroplasia (ACH). Extracellular signal regulated kinase (ERK) phosphorylation was attenuated by meclozine in FGF2-treated chondrocyte cell line,
Externí odkaz:
https://doaj.org/article/c34b8201d58b4d52b95eea27a34b8859
Autor:
Shinya Kaneko, Masaki Matsushita, Kenichi Mishima, Yasuhiko Takegami, Shiro Imagama, Hiroshi Kitoh
Publikováno v:
Bone Reports, Vol 13, Iss , Pp 100708- (2020)
Achondroplasia (ACH) is the most common form of short-limbed skeletal dysplasia. Patients with ACH sometimes undergo lower limb lengthening to get functional and psychological achievements. The periosteal resection (PR) is a known mechanism to increa
Externí odkaz:
https://doaj.org/article/a2bcd54bc5a541f09ae29b254ffd2813