Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Hiroshi Ibe"'
Autor:
Rishu Takimoto, Takashi Kamigaki, Takuji Gotoda, Toshimi Takahashi, Sachiko Okada, Hiroshi Ibe, Eri Oguma, Shigenori Goto
Publikováno v:
Journal of Medical Case Reports, Vol 15, Iss 1, Pp 1-8 (2021)
Abstract Background Blocking the programmed death 1 pathway by immune checkpoint inhibitors induces dramatic antitumor activity in patients with malignant tumors. However, the clinical response to immune checkpoint inhibitors remains limited owing to
Externí odkaz:
https://doaj.org/article/3f53ba5655b64d9ca3fc37d75d622aee
Publikováno v:
Anticancer Research. 41:4133-4141
Background/aim Advanced/recurrent breast cancer (ARBC) still has a poor prognosis; therefore, new treatment strategies are required. In this retrospective study, we aimed to investigate the efficacy of immune-cell therapy using T lymphocytes activate
Publikováno v:
Anticancer research. 42(8)
The efficacy of adjuvant systemic therapy after surgical resection remains unsatisfactory; therefore, a new treatment strategy is required. We aimed to examine the efficacy of adjuvant immune-cell therapy using activated T lymphocytes with or without
Autor:
Tomoharu Miyashita, Sachiko Okada, Keiko Naitoh, Eri Oguma, Takashi Kamigaki, Kaori Makita, Hiroshi Ibe, Katsuro Tomita, Kosei Yasumoto, Shigenori Goto, Rishu Takimoto, Eishiro Mizukoshi
Publikováno v:
Cytotherapy. 22:329-336
Background aims Activated γδT cells have been shown to exhibit cytotoxicity against tumor cells. However, the efficacy of γδT cell immunotherapy for a large number of patients with solid tumors remains unclear. In this study, we examined the effi
Autor:
Rishu Takimoto, Shigenori Goto, Eriko Matsuda, Keiko Naitoh, Sachiko Okada, Hiroshi Ibe, Eri Oguma, Takashi Kamigaki, Kaori Makita
Publikováno v:
Anticancer Research. 39:4525-4532
Background/aim In this retrospective study, we aimed to investigate the efficacy of immune-cell therapy using T lymphocytes activated in vitro with or without dendritic cells vaccination (DCs), in combination with 1st-line chemotherapies in terms of
Autor:
Toshimi Takahashi, Shigenori Goto, Sachiko Okada, Rishu Takimoto, Hiroshi Ibe, Takuji Gotoda, Eri Oguma, Takashi Kamigaki
Publikováno v:
Journal of Medical Case Reports, Vol 15, Iss 1, Pp 1-8 (2021)
Journal of Medical Case Reports
Journal of Medical Case Reports
Background Blocking the programmed death 1 pathway by immune checkpoint inhibitors induces dramatic antitumor activity in patients with malignant tumors. However, the clinical response to immune checkpoint inhibitors remains limited owing to the pati
Autor:
Keiko Naitoh, Shigenori Goto, Eriko Matsuda, Hiroshi Ibe, Eri Oguma, Takashi Kamigaki, Kaori Makita, Sachiko Okada, Rishu Takimoto
Publikováno v:
Anticancer Research. 38:4353-4360
BACKGROUND/AIM The past 17 years, immune-cell therapy has been administered to 990 patients with advanced or recurrent pancreatic adenocarcinoma and 50 patients with curatively resected pancreatic adenocarcinoma. MATERIALS AND METHODS The correlation
Autor:
Keiko Naitoh, Eriko Matsuda, Hiroshi Ibe, Sachiko Okada, Shigenori Goto, Rishu Takimoto, Eri Oguma, Takashi Kamigaki, Kaori Makita
Publikováno v:
Anticancer Research. 37
BACKGROUND Conventional therapy for advanced gastric cancer (GC) has limited survival benefits. In this retrospective study, we aimed to investigate the efficacy of immune-cell therapy, using in vitro-activated T-lymphocytes with and without dendriti
Autor:
Takashi, Kamigaki, Hiroshi, Ibe, Sachiko, Okada, Eriko, Matsuda, Masanori, Tanaka, Eri, Oguma, Yoshihiro, Kinoshita, Shun, Ogasawara, Atsuko, Ono, Kaori, Makita, Keiko, Naitoh, Shigenori, Goto
Publikováno v:
Anticancer research. 35(8)
We evaluated the immunological status of patients with various solid tumors by flow cytometry of immune cell populations and their frequencies in peripheral blood samples. The change in immunological status was also analyzed in patients given autolog
Autor:
Takashi, Kamigaki, Toru, Kaneko, Keiko, Naitoh, Masashi, Takahara, Takashige, Kondo, Hiroshi, Ibe, Eriko, Matsuda, Ryuji, Maekawa, Shigenori, Goto
Publikováno v:
Anticancer research. 33(7)
Dendritic cell (DC)-based vaccines with the use of various antigen loading methods have been developed for cancer immunotherapy. Electroporation (EP) of a whole tumor cell lysate into DCs was previously found to be more potent for eliciting antigen-s