Zobrazeno 1 - 10
of 1 053
pro vyhledávání: '"Hiroshi Handa"'
Autor:
Kei Morikawa, Yu Numata, Yusuke Shinozaki, Shotaro Kaneko, Aya Matsushima, Makoto Nishida, Hirotaka Kida, Hiroshi Handa, Hiroki Nishine, Masamichi Mineshita
Publikováno v:
Thoracic Cancer, Vol 15, Iss 6, Pp 496-499 (2024)
Abstract Anaplastic lymphoma kinase (ALK) fusion gene‐positive lung cancer often shows brain metastasis at initial diagnosis or during the course of treatment. However, molecular‐targeted drugs are known to pass through the blood–brain barrier
Externí odkaz:
https://doaj.org/article/0860e34e98624a1880da4cf689d2bfb3
Autor:
Yu Wang, Shunsuke Shimosaki, Emi Ikebe, Hidekatsu Iha, Jun-ichi Yamamoto, Nichole Fife, Tomonaga Ichikawa, Mitsuo Hori, Masao Ogata, Yoshiyuki Tsukamoto, Naoki Hijiya, Masatsugu Moriyama, Shotaro Hagiwara, Shuichi Kusano, Masumichi Saito, Kamruddin Ahmed, Akira Nishizono, Hiroshi Handa, Kazuhiro Morishita
Publikováno v:
Frontiers in Oncology, Vol 13 (2024)
Adult T-cell leukemia/lymphoma (ATL) is an aggressive T-cell neoplasia associated with human T-cell leukemia virus type 1 (HTLV-1) infection and has an extremely poor prognosis. Lenalidomide (LEN; a second-generation immunomodulatory drug [IMiD]) has
Externí odkaz:
https://doaj.org/article/c652ad6387c14272840172d06da6e59c
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-6 (2023)
Abstract Airway involvement in relapsing polychondritis (RP) can be debilitating and life threatening, often requiring interventional procedures. If standard therapies including systemic corticosteroid and immunosuppressive agents are ineffective, ai
Externí odkaz:
https://doaj.org/article/dc497e3db1b547f69549d80095b603dd
Publikováno v:
BMC Pulmonary Medicine, Vol 23, Iss 1, Pp 1-4 (2023)
Abstract Background Relapsing polychondritis (RP) is a chronic and recurrent inflammatory disease of the cartilage tissues in the body. The cause of RP is unknown, and since it is a rare disease with symptoms that affect multiple organs, diagnosis is
Externí odkaz:
https://doaj.org/article/6c2c81b956c147d9ae93288cef6dd8de
Autor:
Kohei Kinoshita, Kei Morikawa, Hajime Tsuruoka, Motohiro Chosokabe, Hirotaka Kida, Hiroshi Handa, Takeo Inoue, Tomoyuki Miyazawa, Hisashi Saji, Masamichi Mineshita
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract There are few prospective reports of transbronchial lung cryobiopsy (TBLC) for malignant tumors in combination with forceps biopsy. We investigated the clinical parameters in which TBLC is superior to forceps biopsy. This is a prospective co
Externí odkaz:
https://doaj.org/article/d611973f38a7415f9300453507459b12
Autor:
Yasunori Kogure, Hiroshi Handa, Yuta Ito, Masaki Ri, Yuichi Horigome, Masaki Iino, Yoriko Harazaki, Takahiro Kobayashi, Masahiro Abe, Tadao Ishida, Shigeki Ito, Hiromi Iwasaki, Junya Kuroda, Hirohiko Shibayama, Kazutaka Sunami, Hiroyuki Takamatsu, Hideto Tamura, Toshiaki Hayashi, Kiwamu Akagi, Tomohiro Shinozaki, Takahiro Yoshida, Ikuo Mori, Shinsuke Iida, Takahiro Maeda, Keisuke Kataoka
Publikováno v:
HemaSphere, Vol 7, p e2665764 (2023)
Externí odkaz:
https://doaj.org/article/11421b9993d24536a7fba78bfcb51424
Publikováno v:
Journal of International Medical Research, Vol 51 (2023)
Recently, several biologics have been approved for the treatment of severe asthma. Dupilumab, a biologic used to treat severe asthma, is a monoclonal antibody targeting interleukin-4 and interleukin-13. In the present case, inhaled corticosteroid-ind
Externí odkaz:
https://doaj.org/article/59b7aef374124651a3fc6b58297fed27
Autor:
Manato Sugisaki, Kenji Imamura, Yukie Terasaki, Hiromasa Iino, Takumi Hoshino, Nahoko Hatsumi, Hiroshi Handa, Satoru Takada
Publikováno v:
SAGE Open Medical Case Reports, Vol 11 (2023)
Acute lymphoblastic leukemia is typically characterized by leukocytosis, resulting from the uncontrolled proliferation of malignant cells. However, we report an atypical case of acute lymphoblastic leukemia that presented with leukopenia and exhibite
Externí odkaz:
https://doaj.org/article/be0ffcd4d28e4820b2d103e215cd567a
Autor:
Takaomi Seki, Mariko Tsukagoshi, Norifumi Harimoto, Kenichiro Araki, Akira Watanabe, Norihiro Ishii, Kei Hagiwara, Kouki Hoshino, Ryo Muranushi, Satoru Kakizaki, Yoshiyuki Ogawa, Hiroshi Handa, Ken Shirabe
Publikováno v:
Surgical Case Reports, Vol 8, Iss 1, Pp 1-7 (2022)
Abstract Background Factor V (FV) deficiency is an extremely rare disease, with an incidence of 1 in 1 million. The bleeding symptoms are mild, and the prognosis is good; however, the safety of surgical treatment is unclear, because there are few ava
Externí odkaz:
https://doaj.org/article/141096e3f393462daab3c8d5f537c8e1
Autor:
Hiroshi Handa, June-Won Cheong, Yasushi Onishi, Hiroatsu Iida, Yukio Kobayashi, Hyeoung-Joon Kim, Tzeon-Jye Chiou, Koji Izutsu, Olga Tsukurov, Xiaofei Zhou, Helene Faessel, Ying Yuan, Farhad Sedarati, Douglas V. Faller, Akiko Kimura, Shang-Ju Wu
Publikováno v:
Journal of Hematology & Oncology, Vol 15, Iss 1, Pp 1-5 (2022)
Abstract Pevonedistat, the first small-molecule inhibitor of NEDD8-activating enzyme, has demonstrated clinical activity in Western patients with acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS). We report findings from a phase 1/1b s
Externí odkaz:
https://doaj.org/article/16e57d9cb04a4e2ea784bdfdd8aa57cf