Zobrazeno 1 - 10
of 94
pro vyhledávání: '"Hiroshi Hanafusa"'
Autor:
Naoki Hisamoto, Anna Tsuge, Strahil Iv. Pastuhov, Tatsuhiro Shimizu, Hiroshi Hanafusa, Kunihiro Matsumoto
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Apoptotic cells display surface signals such as phosphatidlyserines that are recognized by phagocytes via engulfment signal receptors. Here, the authors show how one such receptor, transthyretin-like protein 11, plays a role in initiating axon regene
Externí odkaz:
https://doaj.org/article/8dd579fe8d4b4a528c89dbc5c4118828
Autor:
Tatsuhiro Shimizu, Strahil Iv. Pastuhov, Hiroshi Hanafusa, Kunihiro Matsumoto, Naoki Hisamoto
Publikováno v:
Cell Reports, Vol 24, Iss 7, Pp 1880-1889 (2018)
Summary: The ability of specific neurons to regenerate their axons after injury is governed by cell-intrinsic regeneration pathways. However, the mechanisms regulating axon regeneration are not well understood. Here, we identify the brc-2 gene encodi
Externí odkaz:
https://doaj.org/article/3628958288f344589eaab43a5f0a5af7
Autor:
Hiroshi Hanafusa, Keitaro Fujita, Misa Kamio, Shiori Iida, Yasushi Tamura, Naoki Hisamoto, Kunihiro Matsumoto
Publikováno v:
Journal of Cell Science. 136
Proper control of epidermal growth factor receptor (EGFR) signaling is important for maintaining cellular homeostasis. Given that EGFR signaling occurs at the plasma membrane and endosomes following internalization, endosomal trafficking of EGFR spat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ab17953414f38a9b10f3ef113fdecd8
https://doi.org/10.1242/jcs.260566
https://doi.org/10.1242/jcs.260566
Autor:
Hiroshi Hanafusa, Shin Kedashiro, Mako Gotoh, Ko-hei Saitoh, Hironori Inaba, Tomoki Nishioka, Kozo Kaibuchi, Masaki Inagaki, Naoki Hisamoto, Kunihiro Matsumoto
Publikováno v:
Journal of Cell Science. 135
Primary cilia are antenna-like organelles that regulate growth and development via extracellular signals. However, the molecular mechanisms underlying cilia dynamics, particularly those regulating their disassembly, are not well understood. Here, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f36f4d66bcdbc8c52a3b454bdbcfcc8d
https://doi.org/10.1242/jcs.259999
https://doi.org/10.1242/jcs.259999
Publikováno v:
EMBO reports. 23
Histidine phosphorylation is an emerging noncanonical protein phosphorylation in animals, yet its physiological role remains largely unexplored. The protein histidine phosphatase (PHPT1) was recently identified for the first time in mammals. Here, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51d27d11202c3e242dc676601539a370
https://doi.org/10.15252/embr.202255076
https://doi.org/10.15252/embr.202255076
Autor:
Hiroshi Hanafusa, Naoki Hisamoto, Strahil Iv. Pastuhov, Tatsuhiro Shimizu, Kunihiro Matsumoto, Yoshiki Sakai
Publikováno v:
The Journal of Neuroscience
The breast cancer susceptibility protein BRCA1 and its partner BRCA1-associated RING domain protein 1 (BARD1) form an E3-ubiquitin (Ub) ligase complex that acts as a tumor suppressor in mitotic cells. However, the roles of BRCA1–BARD1 in postmitoti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dc19780ac08c43f8a0ba5aa6baa1c06
https://doi.org/10.1523/jneurosci.1806-20.2021
https://doi.org/10.1523/jneurosci.1806-20.2021
Autor:
Hiroshi Hanafusa, Yoshiki Sakai, Naoki Hisamoto, Strahil Iv. Pastuhov, Yasuko Todoroki, Tatsuhiro Shimizu, Kunihiro Matsumoto
Publikováno v:
The Journal of Neuroscience
In Caenorhabditis elegans, axon regeneration is activated by a signaling cascade through the receptor tyrosine kinase (RTK) SVH-2. Axonal injury induces svh-2 gene expression by degradation of the Mad-like transcription factor MDL-1. In this study, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d95f83a783ddd5c46cfe1f5736dc5d56
https://doi.org/10.1523/jneurosci.1024-20.2021
https://doi.org/10.1523/jneurosci.1024-20.2021
Autor:
Mayuka Tsunekawa, Yoshiki Sakai, Naoki Hisamoto, Hiroshi Hanafusa, Kohei Ohta, Kunihiro Matsumoto, Strahil Iv. Pastuhov, Tatsuhiro Shimizu
Publikováno v:
The Journal of Neuroscience
Axon regeneration is an evolutionarily conserved process essential for restoring the function of damaged neurons. InCaenorhabditis eleganshermaphrodites, initiation of axon regeneration is regulated by the RhoA GTPase–ROCK (Rho-associated coiled-co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ac31e9f6bea7c1cef94cced63c9cc14
http://europepmc.org/articles/PMC8260174
http://europepmc.org/articles/PMC8260174
Autor:
Tatsuhiro Shimizu, Hiroshi Hanafusa, Naoki Hisamoto, Yoshiki Sakai, Kunihiro Matsumoto, Kohei Ohta, Chun Li
Publikováno v:
The Journal of Neuroscience
The postinjury regenerative capacity of neurons is known to be mediated by a complex interaction of intrinsic regenerative pathways and external cues. In Caenorhabditis elegans, the initiation of axon regeneration is regulated by the nonmuscle myosin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a095e9bcd13480c44f16d29a714f2b47
https://pubmed.ncbi.nlm.nih.gov/34429379
https://pubmed.ncbi.nlm.nih.gov/34429379
Autor:
Naoki Hisamoto, Yoshiki Sakai, Kohei Ohta, Tatsuhiro Shimizu, Chun Li, Hiroshi Hanafusa, Kunihiro Matsumoto
Publikováno v:
Journal of Neuroscience; 10/4/2021, Vol. 41 Issue 40, p8309-8320, 12p