Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Hiroshi Ham"'
Autor:
Aye Mya Sithu Shein, Dhammika Leshan Wannigama, Cameron Hurst, Peter N. Monk, Mohan Amarasiri, Thidathip Wongsurawat, Piroon Jenjaroenpun, Phatthranit Phattharapornjaroen, William Graham Fox Ditcham, Puey Ounjai, Thammakorn Saethang, Naphat Chantaravisoot, Vishnu Nayak Badavath, Sirirat Luk-in, Sumanee Nilgate, Ubolrat Rirerm, Sukrit Srisakul, Naris Kueakulpattana, Matchima Laowansiri, S. M. Ali Hosseini Rad, Supaporn Wacharapluesadee, Apaporn Rodpan, Natharin Ngamwongsatit, Arsa Thammahong, Hitoshi Ishikawa, Robin James Storer, Asada Leelahavanichkul, Naveen Kumar Devanga Ragupathi, Annika Y. Classen, Talerngsak Kanjanabuch, Daniel Pletzer, Kazuhiko Miyanaga, Longzhu Cui, Hiroshi Hamamoto, Paul G. Higgins, Anthony Kicic, Tanittha Chatsuwan, Parichart Hongsing, Shuichi Abe
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-20 (2024)
Abstract The increasing occurrence of hospital-associated infections, particularly bacteremia, caused by extensively drug-resistant (XDR) carbapenemase-producing colistin-resistant Klebsiella pneumoniae highlights a critical requirement to discover n
Externí odkaz:
https://doaj.org/article/ca32abaf642b4c4d8c0abc8a3029dd50
Autor:
Yusuke Sugita, Daisuke Muraoka, Ayako Demachi-Okamura, Hiroyasu Komuro, Katsuhiro Masago, Eiichi Sasaki, Yasunori Fukushima, Takuya Matsui, Shuichi Shinohara, Yusuke Takahashi, Reina Nishida, Chieko Takashima, Teppei Yamaguchi, Yoshitsugu Horio, Kana Hashimoto, Ichidai Tanaka, Hiroshi Hamana, Hiroyuki Kishi, Daiki Miura, Yuki Tanaka, Kousuke Onoue, Kazuhide Onoguchi, Yoshiko Yamashita, Richard Stratford, Trevor Clancy, Rui Yamaguchi, Hiroaki Kuroda, Hironori Ishibashi, Kenichi Okubo, Hirokazu Matsushita
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
Isolation of tumor-specific T cells and their antigen receptors (TCRs) from malignant pleural effusions (MPE) may facilitate the development of TCR-transduced adoptive cellular immunotherapy products for advanced lung cancer patients. However, the ch
Externí odkaz:
https://doaj.org/article/bd4e64d8943a4db78763ab7d7b778ba1
Autor:
Takehiko Tsuno, Takashi Kawaguchi, Ryota Yanaizumi, Junichi Kondo, Keiko Kojima, Takashi Igarashi, Masaki Inoue, Tomofumi Miura, Akime Miyasato, Kanako Azuma, Hiroshi Hamada, Tomoya Saeki, Hironori Mawatari, Hiroyuki Ogura, Akira Kotani, Takuhiro Yamaguchi, Hideki Hakamata
Publikováno v:
Palliative Medicine Reports, Vol 5, Iss 1, Pp 43-52 (2024)
Background: We aimed to gain insight into psychological barriers toward initiation of strong opioid analgesic use in patients with advanced recurrent cancer. Methods: This study included 46 patients who were prescribed with opioid analgesics for adva
Externí odkaz:
https://doaj.org/article/75600faa135a4a018b58b3fb2a0882d7
Autor:
Abdul Hayee, Eiji Kobayashi, Chihiro Motozono, Hiroshi Hamana, Ha Thi Viet My, Takuya Okada, Naoki Toyooka, Satoshi Yamaguchi, Tatsuhiko Ozawa, Hiroyuki Kishi
Publikováno v:
Cells, Vol 13, Iss 20, p 1711 (2024)
The MHC class I-related 1 (MR1) molecule is a non-polymorphic antigen-presenting molecule that presents several metabolites to MR1-restricted T cells, including mucosal-associated invariant T (MAIT) cells. MR1 ligands bind to MR1 molecules by forming
Externí odkaz:
https://doaj.org/article/686f5558a3f74a8d8717db0ad332b392
Autor:
Misa Minegishi, Takahiro Kuchimaru, Kaori Nishikawa, Takayuki Isagawa, Satoshi Iwano, Kei Iida, Hiromasa Hara, Shizuka Miura, Marika Sato, Shigeaki Watanabe, Akifumi Shiomi, Yo Mabuchi, Hiroshi Hamana, Hiroyuki Kishi, Tatsuyuki Sato, Daigo Sawaki, Shigeru Sato, Yutaka Hanazono, Atsushi Suzuki, Takahide Kohro, Tetsuya Kadonosono, Tomomi Shimogori, Atsushi Miyawaki, Norihiko Takeda, Hirofumi Shintaku, Shinae Kizaka-Kondoh, Satoshi Nishimura
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Cancer cells inevitably interact with neighboring host tissue-resident cells during the process of metastatic colonization, establishing a metastatic niche to fuel their survival, growth, and invasion. However, the underlying mechanisms in t
Externí odkaz:
https://doaj.org/article/c373ff5e397541ef903bbdc92c8afb6e
Autor:
Daisuke Kasugai, Taku Tanaka, Takako Suzuki, Yoshinori Ito, Kazuki Nishida, Masayuki Ozaki, Takeo Kutsuna, Toshiki Yokoyama, Hitoshi Kaneko, Ryo Ogata, Ryohei Matsui, Takahiro Goshima, Hiroshi Hamada, Azusa Ishii, Yusuke Kodama, Naruhiro Jingushi, Ken Ishikura, Ryo Kamidani, Masashi Tada, Hideshi Okada, Takanori Yamamoto, Yukari Goto
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundCoronavirus disease 2019 (COVID-19) features a hypercoagulable state, but therapeutic anticoagulation effectiveness varies with disease severity. We aimed to evaluate the dynamics of the coagulation profile and its association with COVID-19
Externí odkaz:
https://doaj.org/article/2780718fcfb44f049d7c8aeee17d011a
Autor:
Benjamin Rothé, Yayoi Ikawa, Zhidian Zhang, Takanobu A Katoh, Eriko Kajikawa, Katsura Minegishi, Sai Xiaorei, Simon Fortier, Matteo Dal Peraro, Hiroshi Hamada, Daniel B Constam
Publikováno v:
PLoS Biology, Vol 21, Iss 9, p e3002302 (2023)
Organ laterality of vertebrates is specified by accelerated asymmetric decay of Dand5 mRNA mediated by Bicaudal-C1 (Bicc1) on the left side, but whether binding of this or any other mRNA to Bicc1 can be regulated is unknown. Here, we found that a CRI
Externí odkaz:
https://doaj.org/article/e4ddd114040a4c738aa6b08683c53627
Autor:
Hiroyuki Kishi, Hirokazu Matsushita, Hiroshi Hamana, Yuki Tanaka, Yusuke Takahashi, Rui Yamaguchi, Hisashi Iwata, Fumiaki Watanabe, Trevor Clancy, Daisuke Muraoka, Shuichi Shinohara, Hiroyasu Komuro, Takuya Matsui, Yusuke Sugita, Ayako Demachi-Okamura, Katsuhiro Masago, Reina Nishida, Yoshiki Shigematsu, Katsutoshi Adachi, Hiroaki Kuroda, Yasunori Fukushima, Chieko Takashima, Takashi Ohki, Takashi Fukuyama, Daiki Miura, Kousuke Onoue, Kazuhide Onoguchi, Yoshiko Yamashita, Richard Stratford, Kiyoshi Doi
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 8 (2023)
Background CD8+tumor infiltrating lymphocytes (TILs) are often observed in non-small cell lung cancers (NSCLC). However, the characteristics of CD8+ TILs, especially T-cell populations specific for tumor antigens, remain poorly understood.Methods Hig
Externí odkaz:
https://doaj.org/article/aa0364e659cf47c3b066373e07d1c880
Publikováno v:
Bio-Protocol, Vol 13, Iss 14 (2023)
Immotile cilia of crown cells at the node of mouse embryos are required for sensing leftward fluid flow that gives rise to the breaking of left-right (L-R) symmetry. The flow-sensing mechanism has long remained elusive, mainly because of difficulties
Externí odkaz:
https://doaj.org/article/16aa0772f8714fa4a386a1e53ca9ae6f
Autor:
Chihiro Motozono, Mako Toyoda, Toong Seng Tan, Hiroshi Hamana, Yoshihiko Goto, Yoshiki Aritsu, Yusuke Miyashita, Hiroyuki Oshiumi, Kimitoshi Nakamura, Seiji Okada, Keiko Udaka, Mizuki Kitamatsu, Hiroyuki Kishi, Takamasa Ueno
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Mutations in the spike of SARS-CoV-2 can result in the escape of the neutralising antibody response but may retain susceptibility to the cellular immune response. Here the authors show the G446S mutation in the spike protein of Omicron BA.1 is associ
Externí odkaz:
https://doaj.org/article/8c5c5a990c0e4b02b5f94e360a145608