Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Hiroshi Wachi"'
Effect of β-agonist on the dexamethasone-induced expression of aromatase by the human monocyte cells
Publikováno v:
Endocrine Connections, Vol 6, Iss 2, Pp 82-88 (2017)
Emerging evidence suggests that sex steroids are important for human skin health. In particular, estrogen improves skin thickness, elasticity and moisture of older women. The major source of circulating estrogen is the ovary; however, local estrogen
Externí odkaz:
https://doaj.org/article/e808246f68df4173ba8f4f266a1a41fb
Autor:
Shinji Shimoda, Satoru Hashimoto, Ryutaro Mizue, Hiroshi Wachi, Takashi Kamihira, Yutaka Nagata, Yoko Minamikawa, Yasunori Ichiki, Takashi Hirata
Publikováno v:
Kanzo. 62:494-500
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c424bd5d8d68a5dc5118a7957c453345
https://doi.org/10.2957/kanzo.62.494
https://doi.org/10.2957/kanzo.62.494
Autor:
Mika, Hirose, Toyoaki, Kobayashi, Nao, Tanaka, Ayame, Mikagi, Hiroshi, Wachi, Yuki, Mizutani, Toyonobu, Usuki
Publikováno v:
Bioorganicmedicinal chemistry. 52
Desmosine and isodesmosine are crosslinking amino acids of elastin, which is an essential component of the dermal extracellular matrix protein. Quantitative analysis of crosslinker desmosines in human skin dermis has not been fully achieved due to th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a330d52e810c8c55725b3a223c7660de
https://pubmed.ncbi.nlm.nih.gov/34839160
https://pubmed.ncbi.nlm.nih.gov/34839160
Autor:
Toyonobu Usuki, Toyoaki Kobayashi, Nao Tanaka, Hiroshi Wachi, Yuki Mizutani, Mika Hirose, Ayame Mikagi
Publikováno v:
Bioorganic & Medicinal Chemistry. 52:116519
Desmosine and isodesmosine are crosslinking amino acids of elastin, which is an essential component of the dermal extracellular matrix protein. Quantitative analysis of crosslinker desmosines in human skin dermis has not been fully achieved due to th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78f6afbb345ed2b031edbd6ad7f6c58a
https://doi.org/10.1016/j.bmc.2021.116519
https://doi.org/10.1016/j.bmc.2021.116519
Publikováno v:
Biological & Pharmaceutical Bulletin. 40:1646-1653
The cross-linking of elastin by lysyl oxidase (LOX) family members is essential for the integrity and elasticity of elastic fibers, which play an important role in the characteristic resilience of various tissues. However, the temporal sequence of ox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fab208fd4b20b21398036974f4106260
https://doi.org/10.1248/bpb.b17-00027
https://doi.org/10.1248/bpb.b17-00027
Autor:
Hiroshi Wachi, Daigo Wakana, Ken-ichi Kawai, Takeshi Itabashi, Takashi Yaguchi, Kazuki Ishikawa, Tomoo Hosoe, Fumiaki Sato, Hisashi Takeda
Publikováno v:
Journal of Natural Products. 79:2167-2174
Seven novel spiromeroterpenoids, asnovolins A-G (1-7), one of which was shown to suppress fibronectin expression, were isolated from Aspergillus novofumigatus CBS117520 along with a known compound, novofumigatonin (8). The structures of asnovolins A-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::530478b89c9e6d42cabd8a596d8db4fb
https://doi.org/10.1021/acs.jnatprod.6b00013
https://doi.org/10.1021/acs.jnatprod.6b00013
Publikováno v:
Genes to Cells. 20:982-991
Vascular calcification is known to reduce the elasticity of aorta. Several studies have suggested that autophagy-lysosomal pathway (ALP) in vascular smooth muscle cells (VSMCs) is associated with vascular calcification. A major component of oxidized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68f11975e5b56c04cc7ca08919f1af41
https://doi.org/10.1111/gtc.12301
https://doi.org/10.1111/gtc.12301
Publikováno v:
Biological and Pharmaceutical Bulletin. 37:698-702
Elastic fiber assembly is a complex stepwise process involving multiple different proteins and enzymes. Domain 36, encoded by the last exon of the elastin gene, is recognized to be an important domain for deposition onto microfibrils, an essential st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7b402c7ac22d05c8fe12a6821654fd9
https://doi.org/10.1248/bpb.b13-00933
https://doi.org/10.1248/bpb.b13-00933
Publikováno v:
Journal of Atherosclerosis and Thrombosis. 21:463-476
Aim Vascular calcification, an independent risk factor for cardiovascular disease in patients with chronic kidney disease(CKD), refers to the mineralization of vascular smooth muscle cells(VSMCs) caused by phenotypic changes toward osteoblast-like ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ead687613d1a95aadd0bda62527ea53a
https://doi.org/10.5551/jat.20818
https://doi.org/10.5551/jat.20818
Autor:
Satoshi Yoshida, Suzuki, Yasushi A., Yoshihiko Hirata, Yoshiki Kusunoki, Takeshi Itabashi, Masanao Sasatsu, Hiroshi Wachi
Publikováno v:
Pharmacometrics / Ōyō Yakuri (0300-8533); Jun2020, Vol. 98 Issue 5/6, p69-76, 8p