Zobrazeno 1 - 10
of 841
pro vyhledávání: '"Hiroshi , OHNO"'
Autor:
Yuki Hirata, Yoshiki Tanaka, Haruka Yokota, Hiroshi Ohno, Koji Nishida, Hikaru Shimizu, Noboru Mizuta, Kei Nakazawa, Ryoji Koshiba, Kazuki Kakimoto, Takako Miyazaki, Shiro Nakamura, Hiroki Nishikawa
Publikováno v:
Gut Pathogens, Vol 16, Iss 1, Pp 1-5 (2024)
Abstract Background Immune checkpoint inhibitors (ICIs) are crucial in cancer treatment; however, they carry the risk of immune-related adverse events (irAEs), such as enteritis. Case presentation: This study investigated the role of the gut microbio
Externí odkaz:
https://doaj.org/article/2133d2f175724209a0931aea4e11aea9
Autor:
Itsuka Kamimura, Eiji Miyauchi, Tadashi Takeuchi, Noriaki Tsuchiya, Kanami Tamura, Ayumi Uesugi, Hiroki Negishi, Takashi Taida, Tamotsu Kato, Masami Kawasumi, Miho Nagasawa, Kazutaka Mogi, Hiroshi Ohno, Takefumi Kikusui
Publikováno v:
Animal Microbiome, Vol 6, Iss 1, Pp 1-12 (2024)
Abstract Background The gut microbiota plays an important role in the development of behavior and immunity in infants and juveniles. Early weaning (EW), a form of social stress in mice, leads to increased anxiety and an enhanced stress response in th
Externí odkaz:
https://doaj.org/article/557e392edb534706a53d5133d343216c
Lactobacillus paracasei subsp. paracasei 2004 improves health and lifespan in Caenorhabditis elegans
Autor:
Saya Kishimoto, Masanori Nono, Yutaka Makizaki, Yoshiki Tanaka, Hiroshi Ohno, Eisuke Nishida, Masaharu Uno
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Recent research has highlighted the importance of the gut microbiome in regulating aging, and probiotics are interventions that can promote gut health. In this study, we surveyed several novel lactic acid bacteria to examine their beneficial
Externí odkaz:
https://doaj.org/article/7ac2d4bf3b534356a277d718c3490080
Autor:
Takaharu Sasaki, Yuna Ota, Yui Takikawa, Tommy Terrooatea, Takashi Kanaya, Masumi Takahashi, Naoko Taguchi-Atarashi, Naoko Tachibana, Haruka Yabukami, Charles D. Surh, Aki Minoda, Kwang Soon Kim, Hiroshi Ohno
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Food components suppressing small intestinal tumorigenesis are not well-defined partly because of the rarity of this tumor type compared to colorectal tumors. Using Apcmin/+ mice, a mouse model for intestinal tumorigenesis, and antigen-free diet, we
Externí odkaz:
https://doaj.org/article/b2022fef230e4aeb9ab5c82e9ca2641f
Autor:
Yusuke Kinashi, Keisuke Tanaka, Shunsuke Kimura, Masato Hirota, Seiga Komiyama, Tomoko Shindo, Akinori Hashiguchi, Daisuke Takahashi, Shinsuke Shibata, Shin-Ichiro Karaki, Hiroshi Ohno, Koji Hase
Publikováno v:
EBioMedicine, Vol 106, Iss , Pp 105256- (2024)
Summary: Background: Intestinal epithelial cells (IECs) serve as robust barriers against potentially hostile luminal antigens and commensal microbiota. Epithelial barrier dysfunction enhances intestinal permeability, leading to leaky gut syndrome (LG
Externí odkaz:
https://doaj.org/article/8ccf4f716dee42168b9fba259ad46b8a
Autor:
Ryohei Shibata, Naoka Itoh, Yumiko Nakanishi, Tamotsu Kato, Wataru Suda, Mizuho Nagao, Tsutomu Iwata, Hideo Yoshida, Masahira Hattori, Takao Fujisawa, Naoki Shimojo, Hiroshi Ohno
Publikováno v:
Allergology International, Vol 73, Iss 1, Pp 126-136 (2024)
Background: Oral immunotherapy (OIT) can ameliorate cow's milk allergy (CMA); however, the achievement of sustained unresponsiveness (SU) is challenging. Regarding the pathogenesis of CMA, recent studies have shown the importance of gut microbiota (M
Externí odkaz:
https://doaj.org/article/0abd1b7c42d14a21bffc32327a19b1ff
Autor:
Conny Tanjung, Bahrul Fikri, Titis Prawitasari, Nasrum Massi, Andi Alfian Zainuddin, Aidah Juliaty, Dwi Sora Yullyana, Sarah Dwitya, Naoki Shimojo, Hiroshi Ohno, Berthold Koletzko
Publikováno v:
Nutrients, Vol 16, Iss 17, p 2832 (2024)
Weight faltering (WF) has been associated with stunting and with long-term adverse consequences for health and development. Nutritional care for managing WF may consist of giving nutritional advice (NA) and/or provision of oral nutrition supplements
Externí odkaz:
https://doaj.org/article/8f9215ad721c4398a07c48ba468099ff
Autor:
Kazuaki Matsumoto, Kazuki Okuyama, Tom Sidwell, Motoi Yamashita, Takaho Endo, Naoko Satoh-Takayama, Hiroshi Ohno, Tomohiro Morio, Ellen V. Rothenberg, Ichiro Taniuchi
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BCL11B is a transcription factor with six C2H2-type zinc-finger domains. Studies in mice have shown that Bcl11b plays essential roles in T cell development. Several germline heterozygous BCL11B variants have been identified in human patients with inb
Externí odkaz:
https://doaj.org/article/83c8db04a2b14d88adbf03ead9999ff0
Autor:
Tomoya Tsukimi, Nozomu Obana, Suguru Shigemori, Kazuharu Arakawa, Eiji Miyauchi, Jiayue Yang, Isaiah Song, Yujin Ashino, Masataka Wakayama, Tomoyoshi Soga, Masaru Tomita, Hiroshi Ohno, Hirotada Mori, Shinji Fukuda
Publikováno v:
mSystems, Vol 9, Iss 2 (2024)
ABSTRACTMammalian gut microbes colonize the intestinal tract of their host and adapt to establish a microbial ecosystem. The host diet changes the nutrient profile of the intestine and has a high impact on microbiota composition. Genetic mutations in
Externí odkaz:
https://doaj.org/article/6c21002eaf084c9dbfa695248a4bc888
Autor:
Kayo Ito, Hirokuni Miyamoto, Makiko Matsuura, Chitose Ishii, Yumiko Nakanishi, Wataru Suda, Takashi Satoh, Fuyuko Honda, Atsushi Kurotani, Naoko Tsuji, Teruno Nakaguma, Chie Shindo, Toshiyuki Ito, Ryounosuke Michibata, Ryouichi Yamada, Yosuke Takahashi, Hiroaki Kodama, Jun Kikuchi, Hiroshi Ohno
Publikováno v:
Journal of Functional Foods, Vol 113, Iss , Pp 106001- (2024)
Global warming has become an urgent issue, and heat-stress protective materials should be developed to manage human life and animal husbandry. Here, thermoprotective effects of Weizmannia coagulans SANK70258, a thermostable probiotic lactic acid bact
Externí odkaz:
https://doaj.org/article/b0f0ca8b01b441d89a5bb765ea8110d3