Zobrazeno 1 - 10
of 222
pro vyhledávání: '"Hiroshi, Yasui"'
Autor:
Jiro Kikuchi, Mitsuo Hori, Naoki Osada, Sae Matsuoka, Atsushi Suzuki, Satoshi Kakugawa, Hiroshi Yasui, Takeshi Harada, Hirofumi Tenshin, Masahiro Abe, Hideki Nakasone, Yusuke Furukawa
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
Not available.
Externí odkaz:
https://doaj.org/article/e14a95c44b6d4444a7baef0a978500e9
Autor:
Naoki Osada, Jiro Kikuchi, Hidekatsu Iha, Hiroshi Yasui, Sho Ikeda, Naoto Takahashi, Yusuke Furukawa
Publikováno v:
Clinical and Translational Medicine, Vol 13, Iss 8, Pp n/a-n/a (2023)
Abstract Background The immunomodulatory drug lenalidomide, which is now widely used for the treatment of multiple myeloma (MM), exerts pharmacological action through the ubiquitin‐dependent degradation of IKZF1 and subsequent down‐regulation of
Externí odkaz:
https://doaj.org/article/0a3208aa7bc9414d92ad8a167dd711c6
Autor:
Mitsuhito Hirano, Yoichi Imai, Yuta Kaito, Takahiko Murayama, Kota Sato, Tadao Ishida, Junichi Yamamoto, Takumi Ito, Muneyoshi Futami, Masaki Ri, Hiroshi Yasui, Tamami Denda, Yukihisa Tanaka, Yasunori Ota, Masanori Nojima, Yasuhiko Kamikubo, Noriko Gotoh, Shinsuke Iida, Hiroshi Handa, Arinobu Tojo
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-19 (2021)
Abstract Background Multiple myeloma (MM) is an incurable disease. The acquisition of resistance to drugs, including immunomodulatory drugs (IMiDs), has a negative effect on its prognosis. Cereblon (CRBN) is a key mediator of the bioactivities of IMi
Externí odkaz:
https://doaj.org/article/f2e71599d7d641fb9ece99c28c22cc0d
Autor:
Naoyuki Iso-o, Keisuke Komatsuya, Fuyuki Tokumasu, Noriko Isoo, Tomohiro Ishigaki, Hiroshi Yasui, Hiroshi Yotsuyanagi, Masumi Hara, Kiyoshi Kita
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Malaria parasites cannot multiply in host erythrocytes without cholesterol because they lack complete sterol biosynthesis systems. This suggests parasitized red blood cells (pRBCs) need to capture host sterols, but its mechanism remains unknown. Here
Externí odkaz:
https://doaj.org/article/35b4fa923b6744ca8196c1975c19e9bb
Autor:
Naoki Osada, Jiro Kikuchi, Daisuke Koyama, Yoshiaki Kuroda, Hiroshi Yasui, Joel D. Leverson, Yusuke Furukawa
Publikováno v:
Haematologica, Vol 106, Iss 11 (2021)
Externí odkaz:
https://doaj.org/article/4ef063f73f424606b2a6a9d98867c450
Autor:
Jiro Kikuchi, Nobuyuki Kodama, Masataka Takeshita, Sho Ikeda, Takahiro Kobayashi, Yoshiaki Kuroda, Michihiro Uchiyama, Naoki Osada, Bjarne Bogen, Hiroshi Yasui, Naoto Takahashi, Akiyoshi Miwa, Yusuke Furukawa
Publikováno v:
Blood Advances. 7:508-524
Extramedullary disease (EMD) is known to be associated with chemoresistance and poor prognosis in multiple myeloma (MM); however, the mechanisms of its development are not fully understood. Elucidating the mechanism of EMD development and its therape
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e410fda829e678290a13c83ddf2125f9
https://doi.org/10.1182/bloodadvances.2022007291
https://doi.org/10.1182/bloodadvances.2022007291
Publikováno v:
Journal of the Anus, Rectum and Colon, Vol 1, Iss 1, Pp 22-28 (2017)
Objectives: To evaluate the rules for anal fistulas with scrotal extension, in particular, whether a high transsphincteric or suprasphincteric fistula, of which internal openings are usually located posteriorly, would extend into the scrotum. Methods
Externí odkaz:
https://doaj.org/article/6be573761b2f4968b5369c9ed259eeaf
Autor:
Yusuke Furukawa, Tatsuo Ichinohe, Takakazu Kawase, Hiroshi Yasui, Tohru Izumi, Naoki Osada, Daisuke Koyama, Yoshiaki Kuroda, Jiro Kikuchi
Supplementary Materials and Methods, Tables S1-5, and Figures S1-9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b09ce77226050f4e699a9c6fb4158df0
https://doi.org/10.1158/0008-5472.22417019.v1
https://doi.org/10.1158/0008-5472.22417019.v1
Autor:
Kenneth C. Anderson, Paul Richardson, Nikhil Munshi, Frank Osterroth, Silke Aigner, Benjamin Dälken, Christoph Uherek, Noopur S. Raje, Diana Cirstea, Yu-Tzu Tai, Giulia Perrone, Loredana Santo, Samantha Pozzi, Sonia Vallet, Tanyel Kiziltepe, Yutaka Okawa, Hiroshi Yasui, Robert J. Lutz, Mariateresa Fulciniti, Teru Hideshima, Hiroshi Ikeda
Purpose: We investigated the antitumor effect of murine/human chimeric CD138-specific monoclonal antibody nBT062 conjugated with highly cytotoxic maytansinoid derivatives against multiple myeloma (MM) cells in vitro and in vivo.Experimental Design: W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d21d7bb017be79ca7944f6ef64df7db3
https://doi.org/10.1158/1078-0432.c.6517504.v1
https://doi.org/10.1158/1078-0432.c.6517504.v1
Autor:
Yasuhisa Shinomura, Minoru Toyota, Tadao Ishida, Takashi Tokino, Kohzoh Imai, Mitsuru Mori, Toshiaki Hayashi, Hajime Sakai, Hideki Asaoku, Yasushi Sasaki, Isao Tarasawa, Yumiko Maruyama, Hiromu Suzuki, Hiroshi Yasui, Reo Maruyama, Masanori Nojima
Supplementary Data from Genomic Screening for Genes Silenced by DNA Methylation Revealed an Association between RASD1 Inactivation and Dexamethasone Resistance in Multiple Myeloma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1149dd8ac2b359dfd3aeca7213988a0a
https://doi.org/10.1158/1078-0432.22440073.v1
https://doi.org/10.1158/1078-0432.22440073.v1