Zobrazeno 1 - 10 of 98 pro vyhledávání: '"Hiroshi, Takei"'
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Akademický článek
Interleukin-17A is a potential therapeutic target predicted by proteomics for systemic sclerosis patients at high risk of pulmonary arterial hypertension
Autor: Yuuichi Ono, Akira Mogami, Ryuta Saito, Noriyasu Seki, Sho Ishigaki, Hiroshi Takei, Keiko Yoshimoto, Kenji Chiba, Tsutomu Takeuchi, Yuko Kaneko
Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract We explored effective therapeutic targets for systemic sclerosis (SSc) patients with high risk for pulmonary arterial hypertension (PAH) by plasma proteomics analysis. A total of fifty-seven patients with SSc were enrolled in the study and t
Externí odkaz: https://doaj.org/article/b04c96d973a0474189d1857fbc9ccb8c
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2
Akademický článek
Aryl hydrocarbon receptor signals attenuate lung fibrosis in the bleomycin-induced mouse model for pulmonary fibrosis through increase of regulatory T cells
Autor: Hiroshi Takei, Hidekata Yasuoka, Keiko Yoshimoto, Tsutomu Takeuchi
Publikováno v: Arthritis Research & Therapy, Vol 22, Iss 1, Pp 1-10 (2020)
Abstract Background Interstitial lung disease (ILD) is a serious complication of connective tissue diseases (CTDs). Although immune dysregulation triggered by genetic and environmental factors is thought to provoke inflammation and subsequent fibrosi
Externí odkaz: https://doaj.org/article/5865c9291f204c879b58630a1b58bb1a
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4
Dermatomyositis Which Was Double Positive for Anti-MDA5 and Anti-ARS Antibodies That Was Successfully Treated by Intensive Immunosuppressive Therapy
Autor: Satoshi, Hama, Misako, Higashida-Konishi, Mitsuhiro, Akiyama, Tatsuya, Shimada, Hiroshi, Takei, Keisuke, Izumi, Hisaji, Oshima, Yutaka, Okano
Publikováno v: Internal Medicine. 61:1085-1091
Myositis-specific autoantibody is associated with the clinical phenotype and prognosis of dermatomyositis. Anti-melanoma differentiation-associated gene 5 (MDA5) and anti-aminoacyl-tRNA synthetase (ARS) antibodies are generally mutually exclusive. We
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b87a59abd5c7a7b2250b8e300822d7d2
https://doi.org/10.2169/internalmedicine.8579-21
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6
Early combination of pulmonary vasodilators prevents chronic kidney disease progression in connective tissue disease‐associated pulmonary hypertension
Autor: Shuntaro Saito, Sho Ishigaki, Kazuoto Hiramoto, Yasushi Kondo, Hiroshi Takei, Yuko Kaneko, Jun Kikuchi, Tsutomu Takeuchi, Hironari Hanaoka
Publikováno v: International Journal of Rheumatic Diseases. 24:1419-1426
Aim Pulmonary hypertension (PH) and chronic kidney disease (CKD) are interdependent for their development and exacerbation. We evaluated the effect of PH on CKD progression in patients with connective tissue disease (CTD)-associated PH. Methods We re
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::587824a6404f453d8f03cfe3b2ead695
https://doi.org/10.1111/1756-185x.14225
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7
Clinical and immunological effects of hydroxychloroquine in patients with active rheumatoid arthritis despite antirheumatic treatment
Autor: Hiroshi Takei, Satoshi Takanashi, Kotaro Otomo, Hironari Hanaoka, Jun Kikuchi, Kunihiro Yamaoka, Keiko Yoshimoto, Takayuki Abe, Tsutomu Takeuchi, Yuko Kaneko
Publikováno v: Modern rheumatology.
Objectives To investigate the efficacy and safety of hydroxychloroquine (HCQ) in patients with rheumatoid arthritis (RA). Methods Patients with active RA, despite conventional synthetic disease-modifying antirheumatic drugs (csDMARDs), were recruited
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca7647e27699349e8ce06a488f1caef3
https://pubmed.ncbi.nlm.nih.gov/36484525
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8
Rheumatoid arthritis with nontuberculous mycobacterial pulmonary disease: a retrospective, single-centre cohort study
Autor: Hiroshi, Takei, Naoshi, Nishina, Ho, Namkoong, Katsuya, Suzuki, Yoshifumi, Uwamino, Naoki, Hasegawa, Tsutomu, Takeuchi
Publikováno v: Modern Rheumatology. 32:534-540
Objectives Nontuberculous mycobacterial pulmonary disease (NTM-PD) is a rare but important comorbidity of rheumatoid arthritis (RA). Our objective was to investigate the association between NTM-PD and RA, especially regarding the immunosuppressive tr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3613f76bf4824bb915e1dc366090b816
https://doi.org/10.1093/mr/roab032
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9
Successful treatment with tofacitinib for relapse of rapidly progressive interstitial lung disease in anti-melanoma differentiation-associated gene 5 antibody-positive clinically amyopathic dermatomyositis
Autor: Satoshi Hama, Mitsuhiro Akiyama, Misako Higashida-Konishi, Tatsuhiro Oshige, Hiroshi Takei, Keisuke Izumi, Hisaji Oshima, Yutaka Okano
Publikováno v: Modern rheumatology case reports. 7(1)
Anti-melanoma differentiation-associated gene 5 (MDA5) antibody is associated with clinically amyopathic dermatomyositis (CADM) with rapidly progressive interstitial lung disease (RP-ILD). Recently, several studies have reported that tofacitinib (TOF
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::407b105cbdf4fcaa4a0b4c319da37083
https://pubmed.ncbi.nlm.nih.gov/35680682
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