Výsledky vyhledávání - "Hiroshi, Miyakawa"

Akademický článek

Fructo-oligosaccharides ameliorate steatohepatitis, visceral adiposity, and associated chronic inflammation via increased production of short-chain fatty acids in a mouse model of non-alcoholic steatohepatitis

Autor: Atsuko Takai, Kentaro Kikuchi, Mayuko Ichimura, Koichi Tsuneyama, Yuki Moritoki, Kotaro Matsumoto, Hiromichi Tsunashima, Takeshi Onda, Noriyuki Kuniyoshi, Tomoyuki Nariyama, Sho Ohyatsu, Juri Kubota, Kozue Nagumo, Shinpei Sato, Masumi Hara, Hiroshi Miyakawa

Publikováno v: BMC Gastroenterology, Vol 20, Iss 1, Pp 1-10 (2020)

Abstract Background Non-alcoholic fatty liver disease (NAFLD) is a hepatic manifestation of metabolic syndrome. Within the spectrum of NAFLD, non-alcoholic steatohepatitis (NASH) in combination with hepatic inflammation and fibrosis can lead to liver

Externí odkaz: https://doaj.org/article/ddcca9f9c91742eab4f6587f0ec3a8db

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Akademický článek

Characterization of a Treponema denticola ATCC 35405 mutant strain with mutation accumulation, including a lack of phage-derived genes.

Autor: Tadaharu Yokogawa, Keiji Nagano, Mari Fujita, Hiroshi Miyakawa, Masahiro Iijima

Publikováno v: PLoS ONE, Vol 17, Iss 6, p e0270198 (2022)

Trepoenema denticola, a spirochetal bacterium, is associated with periodontal diseases. The type strain of the bacterium, ATCC 35405, is commonly used in a basic research. Here, we report that our stock strain derived from ATCC 35405 had a mutation o

Externí odkaz: https://doaj.org/article/e8d22758a0e04531b2a2eacefc6ac1ac

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Akademický článek

Fructo-oligosaccharides and intestinal barrier function in a methionine-choline-deficient mouse model of nonalcoholic steatohepatitis.

Autor: Kotaro Matsumoto, Mayuko Ichimura, Koichi Tsuneyama, Yuki Moritoki, Hiromichi Tsunashima, Katsuhisa Omagari, Masumi Hara, Ichiro Yasuda, Hiroshi Miyakawa, Kentaro Kikuchi

Publikováno v: PLoS ONE, Vol 12, Iss 6, p e0175406 (2017)

Impairments in intestinal barrier function, epithelial mucins, and tight junction proteins have been reported to be associated with nonalcoholic steatohepatitis. Prebiotic fructo-oligosaccharides restore balance in the gastrointestinal microbiome. Th

Externí odkaz: https://doaj.org/article/f9495ea93f8641e9bbb4c6a168e37202

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Akademický článek

Serum Reactivity Against Bacterial Pyruvate Dehydrogenase: Increasing the Specificity of Anti-Mitochondrial Antibodies for the Diagnosis of Primary Biliary Cirrhosis

Autor: Hiroshi Miyakawa, Atsushi Tanaka, Carlo Selmi, Naomi Hosoya, Norikazu Mataki, Kentaro Kikuchi, Takashi Kato, Junya Arai, Toshihiro Goto, M. Eric Gershwin

Publikováno v: Clinical and Developmental Immunology, Vol 13, Iss 2-4, Pp 289-294 (2006)

Antimitochondrial antibodies (AMA) are the serum hallmark of primary biliary cirrhosis (PBC). However, AMA-positivity can be found in non-PBC sera when lower dilutions are used, thus raising issues about the specificity and sensitivity of the test. A

Externí odkaz: https://doaj.org/article/0dae48015e464ee58f90de62cd86611d

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Akademický článek

Serial Analysis of Antimitochondrial Antibody in Patients with Primary Biliary Cirrhosis

Autor: Mitchell R. Watnik, M. Eric Gershwin, Atsushi Tanaka, Gordon D. Benson, Kentaro Kikuchi, Hiroshi Miyakawa

Publikováno v: Clinical and Developmental Immunology, Vol 11, Iss 2, Pp 129-133 (2004)

Externí odkaz: https://doaj.org/article/cee040c79b6141d6acd74195618e48af

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Immunoglobulin G4-related Liver Disease Overlapping with Non-alcoholic Steatohepatitis That Was Diagnosed Simultaneously with Autoimmune Pancreatitis: A Case Report and Review of the Literature

Autor: Hiromichi Tsunashima, Noriyuki Kuniyoshi, Kentaro Kikuchi, Hiroshi Miyakawa, Masatoshi Mabuchi, Katsunori Sekine, Shinpei Doi, Yoh Zen, Kotaro Matsumoto

Publikováno v: Internal Medicine

A 70-year-old woman was referred to our hospital due to symptoms of dry eyes, dry mouth, and epigastric pain. Computed tomography showed distal pancreatic swelling, liver edge dullness and surface irregularities. Serum anti-nuclear antibody titers, i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::880a5b5d551c694ba2392d6751e3dc54
http://europepmc.org/articles/PMC6949448

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Detection of Anti-mitochondrial Antibodies Accompanied by Drug-induced Hepatic Injury due to Atorvastatin

Autor: Kentaro Kikuchi, Shinpei Doi, Noriyuki Kuniyoshi, Takayuki Tsujikawa, Katsunori Sekine, Kotaro Matsumoto, Masatoshi Mabuchi, Hiroshi Miyakawa, Hiromichi Tsunashima

Publikováno v: Internal Medicine

A 44-year-old Japanese woman was admitted to our hospital with fatigue and an altered liver function. She had been receiving atorvastatin treatment for 10 months. Although no jaundice was seen, the patient's serum alkaline phosphatase and γ-glutamyl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e31eb1abdb3b4098138bf5e8cd6cd3c
http://europepmc.org/articles/PMC6794188

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Draft Genome Sequence of Neisseria mucosa Strain HSUH001, Isolated from an Aggressive Periodontal Lesion

Autor: Hiroshi Miyakawa, Toshiyuki Nagasawa, Mari Fujita, Masatoshi Yamashita, Keiji Nagano, Yasushi Furuichi, Satsuki Kato

Publikováno v: Microbiology Resource Announcements

We report the draft genome sequence (143 contigs, with a total length of 2,424,805 bp and an N50 value of 36,066 bp) of a bacterium isolated from an aggressive periodontal lesion in a patient. We assigned strain HSUH001 to Neisseria mucosa through a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b063758379c9f7115a0e3daae5faf28
http://europepmc.org/articles/PMC8142570

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