Výsledky vyhledávání - "Hiroshi, Kuriyama"

AK106-001616, a Potent and Selective Inhibitor of Cytosolic Phospholipase A2: In Vivo Efficacy for Inflammation, Neuropathic Pain, and Pulmonary Fibrosis

Autor: Masakazu Komatsu, Hiroshi Kuriyama, Katsuhiko Sakurada, Akitoshi Ito, Yukiko Endo, Kosuke Tanaka, Tomohito Kozaki, Hirotomo Shimizu, Kenichi Saito, Motoshi Shoda, Junji Nakamura, Mineko Takeda

Publikováno v: Journal of Pharmacology and Experimental Therapeutics. 369:511-522

3-[3-Amino-4-(indan-2-yloxy)-5-(1-methyl-1H-indazol-5-yl)-phenyl]-propionic acid (AK106-001616) is a novel, potent, and selective inhibitor of the cytosolic phospholipase A2 (cPLA2) enzyme. Unlike traditional nonsteroidal anti-inflammatory drugs and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::71324a04fc85b10e740d66bc789e3daf
https://doi.org/10.1124/jpet.118.255034

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Early Effects of Single and Low-Frequency Repeated Administration of Teriparatide, hPTH(1-34), on Bone Formation and Resorption in Ovariectomized Rats

Autor: Hiroshi Kuriyama, Emika Sugimoto, Yukihiro Isogai, Toshinori Ishizuya, Aya Takakura, Ryoko Takao-Kawabata, Ichiro Ikegaki, Osamu Nakazono

Publikováno v: Calcified Tissue International

Intermittent repeated administration of teriparatide (TPTD) has potent anabolic effects on bones in vivo. However, TPTD has both anabolic and catabolic effects on osteoblasts in vitro, and the mechanisms underlying its promotion of bone formation are

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebf4f086833b971a74f31459722bee97
https://doi.org/10.1007/s00223-015-0026-1

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Three-Times-Weekly Administration of Teriparatide Improves Vertebral and Peripheral Bone Density, Microarchitecture, and Mechanical Properties Without Accelerating Bone Resorption in Ovariectomized Rats

Autor: Ichiro Ikegaki, Aya Takakura, Ryoko Takao-Kawabata, Toshinori Ishizuya, Shinya Tanaka, Osamu Nakazono, Hiromi Oda, Yukari Shimazu, Emika Sugimoto, Yukihiro Isogai, Hiroshi Kuriyama

Publikováno v: Calcified Tissue International

Daily and weekly administration of teriparatide (PTH1–34) reduces the risk of osteoporotic bone fractures. However, their effects on markers of bone formation and bone resorption differ. These results indicate that the dosing frequency of teriparat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e61ac2df8ccea1e39377f8d0a4d6d26
https://doi.org/10.1007/s00223-015-9998-0

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Naftopidil inhibits 5-hydroxytryptamine-induced bladder contraction in rats

Autor: Hiroshi Kuriyama, Ken-ichi Tomita, Ken-ichi Kasahara, Ichiro Ikegaki, Takumi Sakai

Publikováno v: European Journal of Pharmacology. 700:194-200

Naftopidil is an α(1D) and α(1A) subtype-selective α(1)-adrenoceptor antagonist that has been used to treat lower urinary tract symptoms of benign prostatic hyperplasia. In this study, we investigated the effects of naftopidil on 5-hydroxytryptami

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::299c0b8d127b4396b14d055960c046f9
https://doi.org/10.1016/j.ejphar.2012.12.022

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Calcitonin ameliorates enhanced arterial contractility after chronic constriction injury of the sciatic nerve in rats

Autor: Tomohisa Ishikawa, Mineko Takeda, Hiroshi Kuriyama, Takeshi Yoshimura, Akitoshi Ito, Shin-ya Saito

Publikováno v: Fundamental & Clinical Pharmacology. 26:315-321

In addition to its regulatory effect on bone mass, calcitonin has been shown to relieve pain and alleviate peripheral circulatory disturbance in patients with Raynaud's syndrome and complex regional pain syndrome. In the present study, we investigate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::38ec93d11431b5fb80768ce8b6ae231c
https://doi.org/10.1111/j.1472-8206.2011.00934.x

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Changes in Cardiorespiratory Responses during Exercise with Acute Exposure to Low, Normal or High Oxygen Concentrations at Normal Air Pressure: in Search of an Effective Exercise Environment for Physical Therapy

Autor: Tetsuya Fujimoto, Mitsuhiro Ookura, Koji Shigeshima, Tadakatu Inaoka, Sumi Sakai, Tomiko Miyazaki, Hiroshi Kuriyama, Takayuki Fujiwara, Hiroshi Yamasaki, Tomoyuki Kashiwa, Kunihiro Katayama

Publikováno v: Rigakuryoho Kagaku. 26:365-369

〔目的〕常圧下における低酸素および高酸素条件への急性暴露が，運動時の呼吸循環応答へ与える影響を検討した．〔対象〕健常成人男性7名．〔方法〕膜分離方式により常圧環境下にお

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d5aa69257afefb5fca3c85fc0f54b9ef
https://doi.org/10.1589/rika.26.365

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The Relationship between Squat Action and Ankle Dorsiflexion Range

Autor: Hiroshi Kuriyama, Tomoyuki Kashiwa, Yoshiya Nakano, Tomiko Miyazaki, Hiroshi Yamasaki, Tadakatsu Inaoka, Yukari Iguchi

Publikováno v: Rigakuryoho Kagaku. 25:209-212

〔目的〕足関節背屈可動域がしゃがみ込み動作時の足圧中心位置および動作の可否に与える影響について検討した。〔対象と方法〕健常成人42名（20.1±2.4歳）に対して足関節背屈可動域�

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2378dab7d0f1e16edc6ef61e04cbfa2f
https://doi.org/10.1589/rika.25.209

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