Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Hiroomi, Watabe"'
Autor:
Hiroomi Watabe
Publikováno v:
Journal of Synthetic Organic Chemistry, Japan. 55:229-234
Autor:
Maki Watanabe, Hideyo Yamaguchi, Hiroomi Watabe, Tomio Takeuchi, Hiromi Tohyama, Shinichi Kondo, Tamio Hiratani, Shigeharu Inoue
Publikováno v:
The Journal of Antibiotics. 50:1042-1051
The mechanism of fungitoxic action of an antifungal antibiotic benanomicin A was studied with intact cells and protoplasts of Saccharomyces cerevisiae as well as with its enzymic preparations. The results obtained are summarized as follows: (1) benan
Autor:
Hiroomi Watabe, Shigeharu Inouye, Toru Sasaki, Masahiro Hatsu, Mieko Nagasawa, Masaji Sezaki, Shinichi Kondo, Shinji Miyadoh, Takashi Shomura
Publikováno v:
The Journal of Antibiotics. 45:320-324
A new antitumor antibiotic SF2575 has been isolated from a culture filtrate of Streptomyces sp. SF2575. The molecular formula was determined to be C40H43NO15 by elemental analysis, mass and 13C NMR spectral analyses. The spectral data revealed SF2575
Publikováno v:
The Japanese journal of antibiotics. 56(6)
We examined the effects of fosfomycin (FOM), norfloxacin (NFLX), kanamycin (KM), chloramphenicol (CP), and ampicillin (ABPC) on the morphology of E. coli O157:H7, and the accumulation (cell fraction) and release (medium fraction) of Shiga toxins (Stx
Autor:
Kazumasa Aizawa, Atsuyuki Shimizu, Shiro Sakakibara, Hiroomi Watabe, Toshihiko Takata, Kyoichi Totsuka
Publikováno v:
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy. 10(2)
Pharmacokinetic and pharmacodynamic (PK/PD) parameters, which are important indices of the therapeutic efficacy of antimicrobials, and the minimum inhibitory concentration (MIC) predictive of clinical efficacy at common clinical doses, were examined
Publikováno v:
The Japanese journal of antibiotics. 56(2)
Antibacterial activity of biapenem (BIPM) against clinical isolates of 8 species between 2000 and 2002 was compared with those of imipenem/cilastatin (IPM/CS), meropenem (MEPM), panipenem/betamipron (PAPM/BP) and ceftazidime (CAZ). The MICs of biapen
Publikováno v:
ChemInform. 34
PF1163A and B are a pair of antifungal agents isolated from a fermentation broth of Penicillium sp. PF1163A inhibited ergosterol synthesis in Saccharomyces cerevisiae, resulting in an accumulation of 4,4-dimethylzymosterol and a decrease of ergostero
Publikováno v:
The Japanese journal of antibiotics. 55(6)
In vitro antibacterial activity of fosfomycin was evaluated by various methods. Strains of methicillin-sensitive Staphylococcus aureus, methicillin-sensitive coagulase-negative Staphylococci and Escherichia coli were much more susceptible when glucos
Autor:
Masaki, Shimizu, Makiko, Tabata, Tetsuro, Hara, Minako, Araake, Hiroomi, Watabe, Takeshi, Nishino
Publikováno v:
The Japanese journal of antibiotics. 55(6)
The in vitro short-term bactericidal activity and accumulation of NM394, the active metabolite of prulifloxacin, was compared with those of ciprofloxacin (CPFX), levofloxacin (LVFX) and gatifloxacin (GFLX), using Staphylococcus aureus, Escherichia co
Publikováno v:
The Japanese journal of antibiotics. 55(6)
The inhibitory activity of NM394, the active form of the prodrug prulifloxacin, against type II topoisomerase from Pseudomonas aeruginosa was compared with those of ciprofloxacin (CPFX), levofloxacin (LVFX) and gatifloxacin (GFLX). The 50% inhibitory