Zobrazeno 1 - 10
of 138
pro vyhledávání: '"Hiroo Ueno"'
Autor:
Hidemasa Matsuo, Kenichi Yoshida, Yasuhito Nannya, Yuri Ito, Aina Inagami, Nana Ito, Shinju Iyoda, Shoji Saito, Yuhki Koga, Hiroshi Moritake, Kiminori Terui, Koji Kawaguchi, Yasuhiro Okamoto, Hideki Nakayama, Miyako Kanno, Moeko Hino, Yusuke Akane, Akiko Inoue, Akira Shimada, Hiroaki Goto, Hiroo Ueno, Junko Takita, Genki Yamato, Norio Shiba, Yasuhide Hayashi, Yuichi Shiraishi, Satoru Miyano, Nobutaka Kiyokawa, Daisuke Tomizawa, Takashi Taga, Akio Tawa, Seishi Ogawa, Souichi Adachi
Publikováno v:
HemaSphere, Vol 7, p e51775a7 (2023)
Externí odkaz:
https://doaj.org/article/b478cedad9be4228b9525726b04942b5
Autor:
Tomoya Isobe, Masatoshi Takagi, Aiko Sato-Otsubo, Akira Nishimura, Genta Nagae, Chika Yamagishi, Moe Tamura, Yosuke Tanaka, Shuhei Asada, Reina Takeda, Akiho Tsuchiya, Xiaonan Wang, Kenichi Yoshida, Yasuhito Nannya, Hiroo Ueno, Ryo Akazawa, Itaru Kato, Takashi Mikami, Kentaro Watanabe, Masahiro Sekiguchi, Masafumi Seki, Shunsuke Kimura, Mitsuteru Hiwatari, Motohiro Kato, Shiro Fukuda, Kenji Tatsuno, Shuichi Tsutsumi, Akinori Kanai, Toshiya Inaba, Yusuke Shiozawa, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Rishi S. Kotecha, Mark N. Cruickshank, Fumihiko Ishikawa, Tomohiro Morio, Mariko Eguchi, Takao Deguchi, Nobutaka Kiyokawa, Yuki Arakawa, Katsuyoshi Koh, Yuki Aoki, Takashi Ishihara, Daisuke Tomizawa, Takako Miyamura, Eiichi Ishii, Shuki Mizutani, Nicola K. Wilson, Berthold Göttgens, Satoru Miyano, Toshio Kitamura, Susumu Goyama, Akihiko Yokoyama, Hiroyuki Aburatani, Seishi Ogawa, Junko Takita
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
The molecular heterogeneity of KMT2A-rearranged infant acute lymphoblastic leukemia (ALL) remains poorly characterised. Here, the authors perform multi-omics analysis for 84 ALL patients and suggest 5 distinct subgroups for risk stratification and pe
Externí odkaz:
https://doaj.org/article/7fee3de7cd6b4b10b237a1df0b62b1d6
Autor:
Erik Johansson, Hiroo Ueno
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract The advances in oral cancer research and therapies have not improved the prognosis of patients with tongue cancer. The poor treatment response of tongue cancer may be attributed to the presence of heterogeneous tumor cells exhibiting stem ce
Externí odkaz:
https://doaj.org/article/2800cd5ec03e4a009571454fc8bc0faf
Autor:
Keisuke Tanaka, Junichi Tanaka, Ryo Aizawa, Mayu Kato-Tanaka, Hiroo Ueno, Kenji Mishima, Matsuo Yamamoto
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract The junctional epithelium (JE) is an epithelial component that attaches directly to the tooth surface and performs the unique function of protecting against bacterial infections; its destruction causes inflammation of the periodontal tissue
Externí odkaz:
https://doaj.org/article/575315c14c354515b51004ea6578055b
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract Although the physiological function of the omentum remains elusive, it has been proposed that it plays an important role in fat storage, immune regulation, and regeneration of injured tissues and organs. Although the omentum undergoes expans
Externí odkaz:
https://doaj.org/article/868aa4ac8f0642d9912e9ac70095290c
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-1 (2021)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/173dcbe0800a4cb8b645de6b346f2dca
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-17 (2017)
The adult mammalian cochlear sensory epithelium consists of mechanosensory hair cells and supporting cells but hair cells cannot regenerate. Here, the authors identify multipotent progenitors that arise fromEya1-expressing otic cells that can regener
Externí odkaz:
https://doaj.org/article/5cd0e2b5a4a4481b8d6ad089c0a2794f
Autor:
Kentaro Watanabe, Shunsuke Kimura, Masafumi Seki, Tomoya Isobe, Yasuo Kubota, Masahiro Sekiguchi, Aiko Sato-Otsubo, Mitsuteru Hiwatari, Motohiro Kato, Akira Oka, Katsuyoshi Koh, Yusuke Sato, Hiroko Tanaka, Satoru Miyano, Tomoko Kawai, Kenichiro Hata, Hiroo Ueno, Yasuhito Nannya, Hiromichi Suzuki, Kenichi Yoshida, Yoichi Fujii, Genta Nagae, Hiroyuki Aburatani, Seishi Ogawa, Junko Takita
Publikováno v:
Oncogene. 41(46):4994-5007
Neuroblastomas require novel therapies that are based on the exploitation of their biological mechanism. To address this need, we analyzed the DNA methylation and expression datasets of neuroblastomas, extracted a candidate gene characterizing the ag
Autor:
Kuniaki Tanaka, Itaru Kato, Yuu Dobashi, Jun‐ichi Imai, Takashi Mikami, Hirohito Kubota, Hiroo Ueno, Mamoru Ito, Seishi Ogawa, Tatsutoshi Nakahata, Junko Takita, Hidemi Toyoda, Chitose Ogawa, Souichi Adachi, Shinya Watanabe, Hiroaki Goto
Publikováno v:
Cancer Science. 113(11):3814-3825
A lack of practical resources in Japan has limited preclinical discovery and testing of therapies for pediatric relapsed and refractory acute lymphoblastic leukemia (ALL), which has poor outcomes. Here, we established 57 patient-derived xenografts (P
Autor:
Azusa Mayumi, Toshihiro Tomii, Takuyo Kanayama, Takashi Mikami, Kuniaki Tanaka, Hiroo Ueno, Hideki Yoshida, Itaru Kato, Machiko Kawamura, Tatsutoshi Nakahata, Junko Takita, Hajime Hosoi, Toshihiko Imamura
Publikováno v:
Cancer Gene Therapy. 29:1930-1938
JAK2 rearrangements can occur in Philadelphia chromosome-like acute lymphoblastic leukemia (Ph-like ALL). Here, we performed functional analysis of the SPAG9::JAK2 fusion, which was identified in a pediatric patient with Ph-like ALL, to establish mol