Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Hiroo Ogi"'
Publikováno v:
PLoS Genetics, Vol 13, Iss 8, p e1006873 (2017)
Checkpoint signaling requires two conserved phosphatidylinositol 3-kinase-related protein kinases (PIKKs): ATM and ATR. In budding yeast, Tel1 and Mec1 correspond to ATM and ATR, respectively. The Tel2-Tti1-Tti2 (TTT) complex connects to the Rvb1-Rvb
Externí odkaz:
https://doaj.org/article/efb33226782741a88d7492e89e63b781
Publikováno v:
PLoS Genetics, Vol 11, Iss 8, p e1005283 (2015)
Telomeres, the ends of linear eukaryotic chromosomes, have a specialized chromatin structure that provides a stable chromosomal terminus. In budding yeast Rap1 protein binds to telomeric TG repeat and negatively regulates telomere length. Here we sho
Externí odkaz:
https://doaj.org/article/2353f09660ad49a6aa447aea0a30fc6b
Publikováno v:
Molecular Biology of the Cell
The FATC domain of Tel1 is studied via introduction of substitution and truncation mutations. It is found to be required for localization to sites of DNA damage and is essential for phosphorylation of exogenous substrates but dispensable for the intr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76ac9aa754938792c04f6e5bbca2740a
https://doi.org/10.1091/mbc.e15-05-0259
https://doi.org/10.1091/mbc.e15-05-0259
Publikováno v:
Cell Cycle
The centromere plays an essential role in accurate chromosome segregation, and defects in its function lead to aneuploidy and thus cancer. The centromere-specific histone H3 variant CENP-A is proposed to be the epigenetic mark of the centromere, as a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11fc3c0fa45f4ab3f89dbf833ccd8397
https://pubmed.ncbi.nlm.nih.gov/28816574
https://pubmed.ncbi.nlm.nih.gov/28816574
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 13, Iss 8, p e1006873 (2017)
PLoS Genetics, Vol 13, Iss 8, p e1006873 (2017)
Checkpoint signaling requires two conserved phosphatidylinositol 3-kinase-related protein kinases (PIKKs): ATM and ATR. In budding yeast, Tel1 and Mec1 correspond to ATM and ATR, respectively. The Tel2-Tti1-Tti2 (TTT) complex connects to the Rvb1-Rvb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67df99de600cd8b826e26f44d0d89ced
http://europepmc.org/articles/PMC5578694
http://europepmc.org/articles/PMC5578694
Autor:
Rashid Abdulle, Risa Kitagawa, Katsumi Kitagawa, Yohei Niikura, Hiroo Ogi, Vishwajeeth Pagala
Publikováno v:
Developmental Cell. 40:7-8
Summary CENP-A is a centromere-specific histone H3 variant that epigenetically determines centromere identity to ensure kinetochore assembly and proper chromosome segregation, but the precise mechanism of its specific localization within centromeric
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e8b998673846ea8fc8cb04156fb5154
https://doi.org/10.1016/j.devcel.2016.12.020
https://doi.org/10.1016/j.devcel.2016.12.020
Publikováno v:
Gene. 414(1-2)
The Cdc7–Dbf4 complex is a conserved serine/threonine protein kinase essential for the initiation of eukaryotic DNA replication. Although an mcm5–bob1 mutation bypasses lethality conferred by mutations in CDC7 or DBF4, the Δcdc7 mcm5–bob1 muta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::def25c893ad99f56c79f2a0665f809a4
https://pubmed.ncbi.nlm.nih.gov/18372119
https://pubmed.ncbi.nlm.nih.gov/18372119
Autor:
Katsunori Sugimoto, Greicy H. Goto, Andreas S. Ivessa, Yukinori Hirano, Hiroo Ogi, Sevil Zencir
Publikováno v:
PLoS Genetics, Vol 11, Iss 8, p e1005283 (2015)
PLoS Genetics
PLoS Genetics
Telomeres, the ends of linear eukaryotic chromosomes, have a specialized chromatin structure that provides a stable chromosomal terminus. In budding yeast Rap1 protein binds to telomeric TG repeat and negatively regulates telomere length. Here we sho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::779f9e5b3ebcb799c625f3536e4a47df
https://doi.org/10.1371/journal.pgen.1005283
https://doi.org/10.1371/journal.pgen.1005283
Autor:
M A Cynthia, N Ramirez, Y Sakuraba, Satoshi Ohta, Michael Arnold, L Xiao, Risa Kitagawa, Katsumi Kitagawa, Hiroo Ogi, C Shen, Peter J. Houghton
Publikováno v:
Oncogenesis
Sgt1/Sugt1, a cochaperone of Hsp90, is involved in several cellular activities including Cullin E3 ubiqutin ligase activity. The high level of Sgt1 expression in colorectal and gastric tumors suggests that Sgt1 is involved in tumorigenesis. Here, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a38155821313aa90b80f7f8444aba20
https://doi.org/10.1038/oncsis.2015.12
https://doi.org/10.1038/oncsis.2015.12