Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Hiroo Nakagawa"'
Autor:
Hayato Akamatsu, Hiroo Nakagawa, Ichiro Matsumaru, Junya Hashizume, Hitomi Harasawa, Yukinobu Kodama, Takashi Miura, Kaname Ohyama
Publikováno v:
Journal of Pharmaceutical Health Care and Sciences, Vol 9, Iss 1, Pp 1-4 (2023)
Abstract Background Fluconazole (FLCZ) inhibits cytochrome P450 (CYP) 2C9, 2C19, and 3A4 and has a drug-drug interaction that potentiates the effects of warfarin and prolong the prothrombin time-international normalized ratio (PT-INR). Although a dru
Externí odkaz:
https://doaj.org/article/49217e61f0364a39ac3252d608d4a5ee
Autor:
Yukinobu Kodama, Ayako Tokunaga, Junya Hashizume, Hiroo Nakagawa, Hitomi Harasawa, Tomoaki Kurosaki, Tadahiro Nakamura, Koyo Nishida, Mikiro Nakashima, Mitsuru Hashida, Shigeru Kawakami, Hitoshi Sasaki
Publikováno v:
Drug Delivery, Vol 28, Iss 1, Pp 542-549 (2021)
We developed a biocompatible splenic vector for a DNA vaccine against melanoma. The splenic vector is a ternary complex composed of plasmid DNA (pDNA), biodegradable dendrigraft poly-L-lysine (DGL), and γ-polyglutamic acid (γ-PGA), the selective up
Externí odkaz:
https://doaj.org/article/fb4c978fa3e54f91a147d0e487eba2de
Autor:
Tomoaki Kurosaki, Yuki Katafuchi, Junya Hashizume, Hitomi Harasawa, Hiroo Nakagawa, Mikiro Nakashima, Tadahiro Nakamura, Chikamasa Yamashita, Hitoshi Sasaki, Yukinobu Kodama
Publikováno v:
Drug Delivery, Vol 28, Iss 1, Pp 1585-1593 (2021)
We previously found that a nanoparticle constructed with an antigen, benzalkonium chloride (BK) and γ-polyglutamic acid (γ-PGA) showed high Th1 and Th2-type immune induction after subcutaneous administration. For prophylaxis of respiratory infectio
Externí odkaz:
https://doaj.org/article/1ae04cee4a2a4aa4a42fa110b05051e5
Autor:
Eri Hamada, Tomoaki Kurosaki, Junya Hashizume, Hitomi Harasawa, Hiroo Nakagawa, Tadahiro Nakamura, Yukinobu Kodama, Hitoshi Sasaki
Publikováno v:
Pharmaceutics, Vol 13, Iss 1, p 126 (2021)
We previously found that a complex comprising plasmid DNA (pDNA), polyethylenimine (PEI), and γ-polyglutamic acid (γ-PGA) had high transgene efficiency without cytotoxicity in vitro and in vivo. However, messenger RNA (mRNA) remains an attractive a
Externí odkaz:
https://doaj.org/article/c3a9ead85c6e4ecdba2438dae4bf38bf
Autor:
Yukinobu Kodama, Mikiro Nakashima, Tadayuki Nagahara, Natsuko Oyama, Junya Hashizume, Hiroo Nakagawa, Hitomi Harasawa, Takahiro Muro, Tomoaki Kurosaki, Chikamasa Yamashita, Mitsuru Hashida, Takashi Kitahara, Hitoshi Sasaki, Shigeru Kawakami, Tadahiro Nakamura
Publikováno v:
Pharmaceutics, Vol 12, Iss 6, p 540 (2020)
The present study investigated a pulmonary delivery system of plasmid DNA (pDNA) and its application to melanoma DNA vaccines. pCMV-Luc, pEGFP-C1, and pZsGreen were used as a model pDNA to evaluate transfection efficacy after inhalation in mice. Nake
Externí odkaz:
https://doaj.org/article/ccca79c866d4453b80411a0836bdca55
Autor:
Hiroo Nakagawa, Satoru Koyanagi, Yukako Kuramoto, Akiko Yoshizumi, Naoya Matsunaga, Hiroshi Shimeno, Shinji Soeda, Shigehiro Ohdo
Publikováno v:
Journal of Pharmacological Sciences, Vol 107, Iss 4, Pp 401-407 (2008)
Circadian synchronization of cell proliferation is observed not only in normal healthy tissues but also in malignant solid tumors. However, the proliferation rhythm of tumor cells is often different from that of normal cells. We reported here that th
Externí odkaz:
https://doaj.org/article/91dac8cd0f6f485888c16b8b106d458c
Autor:
Tomoaki Kurosaki, Takashi Kitahara, Shintaro Fumoto, Koyo Nishida, Kayo Yamamoto, Hiroo Nakagawa, Yukinobu Kodama, Norihide Higuchi, Tadahiro Nakamura, Hitoshi Sasaki
Publikováno v:
Journal of Pharmacy & Pharmaceutical Sciences, Vol 13, Iss 3 (2010)
Purpose. In this study, we developed various ternary complexes of encapsulated polyplexes and lipoplexes using chondroitin sulfate (CS) and investigated their universal usefulness for gene delivery. Methods. To prepare the cationic complexes, pDNA wa
Externí odkaz:
https://doaj.org/article/32c25b7db4a64fc5bf2ef82528e31d41
Publikováno v:
Anticancer Research. 43:2309-2316
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f73c54315a1e6a976e4b7754b33eba83
https://doi.org/10.21873/anticanres.16395
https://doi.org/10.21873/anticanres.16395
Autor:
Hiroo, NAKAGAWA
Publikováno v:
鶴見大学紀要. 第1部, 日本語・日本文学編 = The bulletin of Tsurumi University. Pt. 1, Studies in Japanese language and literature. 60:55-148
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=jairo_______::9cc4eaa48022f47ad7022685a6d76976
http://id.nii.ac.jp/1646/00001304/
http://id.nii.ac.jp/1646/00001304/
Autor:
Takahiro Muro, Fumihiko Ando, Marie Suehiro, Hiroo Nakagawa, Chieko Okuda, Takehiro Matsumoto, Koichi Izumikawa, Masayuki Honda, Hitoshi Sasaki
Publikováno v:
Biological and Pharmaceutical Bulletin. 46:237-244
Community-acquired pneumonia (CAP) is an acute pulmonary parenchymal infection acquired outside the hospital. The utility of blood cultures in inpatients with CAP to reduce mortality and length of hospital stay is controversial. This study aimed to d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::895db86431c685c221a048847a80ee36
https://doi.org/10.1248/bpb.b22-00609
https://doi.org/10.1248/bpb.b22-00609