Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Hironori Yashima"'
Autor:
Michishige Terasaki, Hironori Yashima, Yusaku Mori, Tomomi Saito, Naoto Inoue, Takanori Matsui, Naoya Osaka, Tomoki Fujikawa, Makoto Ohara, Sho-ichi Yamagishi
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 17, p 9724 (2024)
Glucose-dependent insulinotropic polypeptide (GIP) of the incretin group has been shown to exert pleiotropic actions. There is growing evidence that advanced glycation end products (AGEs), senescent macromolecules formed at an accelerated rate under
Externí odkaz:
https://doaj.org/article/1382ef28b30e447390273eed3854eaf1
Autor:
Yusaku Mori, Michishige Terasaki, Naoya Osaka, Tomoki Fujikawa, Hironori Yashima, Tomomi Saito, Yurie Kataoka, Makoto Ohara, Yuichiro Higashimoto, Takanori Matsui, Sho-ichi Yamagishi
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 11, p 5947 (2024)
Type 2 diabetes mellitus (T2DM) is a risk factor for male infertility, but the underlying molecular mechanisms remain unclear. Advanced glycation end products (AGEs) are pathogenic molecules for diabetic vascular complications. Here, we investigated
Externí odkaz:
https://doaj.org/article/e3d217edffaf46f494c5f1b073fc8465
Autor:
Yusaku Mori, Makoto Ohara, Michishige Terasaki, Naoya Osaka, Hironori Yashima, Tomomi Saito, Yurie Otoyama-Kataoka, Takemasa Omachi, Yuichiro Higashimoto, Takanori Matsui, Tomoyasu Fukui, Sho-ichi Yamagishi
Publikováno v:
Biomedicines, Vol 11, Iss 12, p 3112 (2023)
We have developed DNA aptamers that can inhibit the toxic effects of advanced glycation end products (AGE-Apts). We herein evaluated the effects of AGE-Apts on muscle mass and strength in senescence-accelerated mouse prone 8 (SAMP8) mice. Eight-month
Externí odkaz:
https://doaj.org/article/2702c5b64a744305b3a937b78da3457c
Autor:
Naoya Osaka, Yusaku Mori, Michishige Terasaki, Munenori Hiromura, Tomomi Saito, Hironori Yashima, Yoshie Shiraga, Raichi Kawakami, Makoto Ohara, Tomoyasu Fukui, Sho-ichi Yamagishi
Publikováno v:
Journal of International Medical Research, Vol 50 (2022)
Objective Sodium-glucose cotransporter-2 (SGLT2) inhibitors exhibit cardioprotective properties in patients with diabetes. However, SGLT2 is not expressed in the heart, and the underlying molecular mechanisms are not fully understood. We investigated
Externí odkaz:
https://doaj.org/article/70384bedcd3a41af9453288197520c36
Autor:
Michishige Terasaki, Hironori Yashima, Yusaku Mori, Tomomi Saito, Yoshie Shiraga, Raichi Kawakami, Makoto Ohara, Tomoyasu Fukui, Tsutomu Hirano, Yuichiro Yamada, Yutaka Seino, Sho-ichi Yamagishi
Publikováno v:
Biomedicines, Vol 9, Iss 7, p 832 (2021)
Glucose-dependent insulinotropic polypeptide (GIP) has been reported to have an atheroprotective property in animal models. However, the effect of GIP on macrophage foam cell formation, a crucial step of atherosclerosis, remains largely unknown. We i
Externí odkaz:
https://doaj.org/article/a05162f7f8d34e2680a4617c06428ef7
Autor:
Hironori Yashima, Michishige Terasaki, Ami Sotokawauchi, Takanori Matsui, Yusaku Mori, Tomomi Saito, Naoya Osaka, Hideki Kushima, Munenori Hiromura, Makoto Ohara, Tomoyasu Fukui, Sho-ichi Yamagishi
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 23, p 9263 (2020)
Advanced glycation end products (AGEs) are localized in macrophage-derived foam cells within atherosclerotic lesions, which could be associated with the increased risk of atherosclerotic cardiovascular disease under diabetic conditions. Although foam
Externí odkaz:
https://doaj.org/article/0aa9afc65a324aacb66d987d94480a8f
Autor:
Michishige Terasaki, Hironori Yashima, Yusaku Mori, Tomomi Saito, Takanori Matsui, Munenori Hiromura, Hideki Kushima, Naoya Osaka, Makoto Ohara, Tomoyasu Fukui, Tsutomu Hirano, Sho-ichi Yamagishi
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 13, p 4811 (2020)
Dipeptidyl peptidase-4 (DPP-4) inhibitors have been reported to play a protective role against atherosclerosis in both animal models and patients with type 2 diabetes (T2D). However, since T2D is associated with dyslipidemia, hypertension and insulin
Externí odkaz:
https://doaj.org/article/9e285243ee544ee1913dac6d90edfce8
Autor:
Michishige Terasaki, Munenori Hiromura, Yusaku Mori, Kyoko Kohashi, Hideki Kushima, Masakazu Koshibu, Tomomi Saito, Hironori Yashima, Takuya Watanabe, Tsutomu Hirano
Publikováno v:
International Journal of Endocrinology, Vol 2018 (2018)
Dipeptidyl peptidase-4 (DPP-4) inhibitors could have antiatherosclerotic action, in addition to antihyperglycemic roles. Because macrophage foam cells are key components of atherosclerosis, we investigated the effect of the DPP-4 inhibitor teneliglip
Externí odkaz:
https://doaj.org/article/c03cfec54da349afb7f57ce727a311c3
Publikováno v:
Clinical Case Reports, Vol 7, Iss 3, Pp 585-586 (2019)
Key Clinical Message We report a rare but fatal case of emphysematous cystitis (EC) that presented as a typical image of gas bubbles within the urinary bladder wall on computed tomography (CT). This disease has a high mortality rate more than that re
Externí odkaz:
https://doaj.org/article/19f0ccd280a04f4b9e6d15a2bc430b5f
Autor:
Tomoki Fujikawa, Tsutomu Hirano, Takanori Matsui, Naoya Osaka, Ayako Fukase, Nobuko Sato, Tomoyasu Fukui, Hironori Yashima, Yasuyoshi Takahashi, Hideki Kushima, Munenori Hiromura, Sho-ichi Yamagishi, Michishige Terasaki, Yusaku Mori, Hiroe Nagaike, Makoto Ohara, Yo Kohata, Kyoko Shinmura
Publikováno v:
Diabetes Therapy
Introduction Pigment epithelium-derived factor (PEDF) may play a role in cardiometabolic disorders. The aim of this study was to investigate which biochemical and clinical parameters are independently associated with serum PEDF levels in patients wit