Zobrazeno 1 - 10
of 356
pro vyhledávání: '"Hironori K"'
Peripheral blood metabolome predicts mood change-related activity in mouse model of bipolar disorder
Autor:
Hideo Hagihara, Tomoyasu Horikawa, Yasuhiro Irino, Hironori K. Nakamura, Juzoh Umemori, Hirotaka Shoji, Masaru Yoshida, Yukiyasu Kamitani, Tsuyoshi Miyakawa
Publikováno v:
Molecular Brain, Vol 12, Iss 1, Pp 1-10 (2019)
Abstract Bipolar disorder is a major mental illness characterized by severe swings in mood and activity levels which occur with variable amplitude and frequency. Attempts have been made to identify mood states and biological features associated with
Externí odkaz:
https://doaj.org/article/c19c7f28881c48b5a8c16e1d74e5fb89
Autor:
Hideo Hagihara, Tomoyasu Horikawa, Hironori K. Nakamura, Juzoh Umemori, Hirotaka Shoji, Yukiyasu Kamitani, Tsuyoshi Miyakawa
Publikováno v:
Cell Reports, Vol 14, Iss 12, Pp 2784-2796 (2016)
Bipolar disorder, also known as manic-depressive illness, causes swings in mood and activity levels at irregular intervals. Such changes are difficult to predict, and their molecular basis remains unknown. Here, we use infradian (longer than a day) c
Externí odkaz:
https://doaj.org/article/bd10baaa23a441c9ae9753b89fe7b2d4
Autor:
Shiono, Y., Katayama, Y., Hironori, K., Kubo, T., Akasaka, T., Tanaka, N., Yamashita, J., Fujita, H., Matsuo, A., Matsuo, H., Kawase, Y., Kawamura, I., Kakuta, T., Hoshino, M., Sugano, T., Takashima, H., Amano, T., Yokoi, H., Yamamoto, Y., Nozaki, Y., Machida, M., Kobori, M., Kikuchi, T., Ohira, H., Yoshino, H., Ishiguro, H., Wakabayashi, Y., Kondo, T., Terai, H., Suwa, T., Kimura, T., Kawajiri, T., Hirohata, A., Uemura, S., Neishi, Y., Sakamoto, T., Yamada, M., Okeie, K., Hishikari, K., Oguri, M., Uetani, T., Saegusa, T., Yamamoto, F., Shiono, Yasutsugu, Matsuo, Hitoshi, Fujita, Hiroshi, Tanaka, Nobuhiro, Ogasawara, Yasuo, Kawamura, Itta, Katayama, Yosuke, Matsuo, Akiko, Kawase, Yoshiaki, Kakuta, Tsunekazu, Takashima, Hiroaki, Yokoi, Hiroyoshi, Ohira, Hiroshi, Suwa, Satoru, Oguri, Mitsutoshi, Yamamoto, Fumi, Kubo, Takashi, Akasaka, Takashi
Publikováno v:
In JACC: Asia September 2021 1(2):230-241
Autor:
Hagihara, Hideo, Horikawa, Tomoyasu, Nakamura, Hironori K., Umemori, Juzoh, Shoji, Hirotaka, Kamitani, Yukiyasu, Miyakawa, Tsuyoshi
Publikováno v:
In Cell Reports 29 March 2016 14(12):2784-2796
Autor:
Toru Nakamura, Atsutaka Masuda, Makoto Kako, Hirayuki Enomoto, Masaki Kaibori, Yasuyuki Fujita, Kyoko Tanizawa, Tetsuya Ioji, Yoshihiro Fujimori, Kei Fukami, Takuma Hazama, Hideki Iwamoto, Yasukazu Kako, Kaoru Kobayashi, Hironori Koga, Koji Nagafuji, Takayasu Ohtake, Hiroyuki Suzuki, Tomoyuki Takashima, Toshitaka Tsukiyama, Haruki Uojima, Kenichi Yamahara, Koichiro Yamakado, Hidekazu Yamamoto, Kazunori Yoh, Satoshi Yoshihara, Atsuhiko Kawamoto, Shuhei Nishiguchi, Shuzo Kobayashi, Takuji Torimura, Takumi Kawaguchi
Publikováno v:
Regenerative Therapy, Vol 27, Iss , Pp 455-463 (2024)
Introduction: In this multicenter clinical study, we aimed to investigate the efficacy and safety of the transhepatic arterial administration of granulocyte-colony stimulating factor (G–CSF)–mobilized autologous peripheral blood (PB)-CD34+ cells
Externí odkaz:
https://doaj.org/article/b19699346ecd4bd1940b165cd426aae3
Autor:
Takuya Sakamoto, Atsushi Fuku, Tetsuhiro Horie, Hironori Kitajima, Yuka Nakamura, Ikuhiro Tanida, Hiroshi Sunami, Hiroaki Hirata, Yoshiyuki Tachi, Yasuo Iida, Sohsuke Yamada, Naoki Yamamoto, Yusuke Shimizu, Yasuhito Ishigaki, Toru Ichiseki, Ayumi Kaneuji, Satoshi Osawa, Norio Kawahara
Publikováno v:
Regenerative Therapy, Vol 27, Iss , Pp 408-418 (2024)
Introduction: Administration of adipose-derived stem cells (ADSCs) into the joint cavity has been shown to alleviate the symptoms of knee osteoarthritis (OA) by releasing exosomes and anti-inflammatory cytokines. However, the therapeutic effect of th
Externí odkaz:
https://doaj.org/article/5db03e3e0b08483f918dd97cfe2fb99c
Autor:
Takumi Kanata, Kazuyoshi Takeda, Takeshi Fujii, Ryo Iwata, Fumikazu Hiyoshi, Yuka Iijima, Tomohiro Nakao, Keitaro Murayama, Koichiro Watanabe, Toshiaki Kikuchi, Masaru Mimura, Asuka Yoshimi, Akitoyo Hishimoto, Hitoshi Hirata, Norio Ozaki, Shinsuke Kito, Hironori Kuga, Mari Oba, Hideki Oi, Kazuyuki Nakagome
Publikováno v:
BMC Psychiatry, Vol 24, Iss 1, Pp 1-11 (2024)
Abstract Background To identify risk factors for mental distress and investigate whether the factors were different between men and women during the coronavirus disease 2019 (COVID-19), using KOKOROBO data, which is an online platform that aims to fa
Externí odkaz:
https://doaj.org/article/18355061ebe14d119438f12925914637
Autor:
Etsuko Moriyama, Shigeo Shimose, Takashi Niizeki, Hideki Iwamoto, Masatoshi Tanaka, Tomotake Shirono, Yu Noda, Masahito Nakano, Ryoko Kuromatsu, Hironori Koga, Takumi Kawaguchi
Publikováno v:
Current Oncology, Vol 31, Iss 10, Pp 5821-5831 (2024)
This retrospective study aimed to evaluate the impact of atezolizumab plus bevacizumab–transcatheter arterial chemoembolization (TACE) sequential therapy in unresectable hepatocellular carcinoma (HCC), especially in patients with intermediate-stage
Externí odkaz:
https://doaj.org/article/d77367d9de414f0eabdaebb91dca7b40
Autor:
Yamada, Kazunori, Koyama, Hiroko, Hagiwara, Kyoji, Ueda, Atsushi, Sasaki, Yutaka, Kanesashi, Shin-nosuke, Ueno, Ryuki, Nakamura, Hironori K., Kuwata, Kazuo, Shimizu, Kazufumi, Suzuki, Masaaki, Aida, Yoko
Publikováno v:
In Microbes and Infection August 2012 14(9):740-747
Publikováno v:
The Journal of Physical Chemistry B. 124:9977-9986
Cryptic sites are binding pockets that are transiently formed in an apo form or that are induced by ligand binding. The investigation of cryptic sites is crucial for drug discovery, since these sites are ubiquitous in disease-related human proteins,