Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Hironori Hamano"'
Autor:
Yoshio Hayashi, Hironori Hamano, Mariko Takahashi, Naozumi Ishimaru, Norio Haneji, Yanagi Kumiko
Publikováno v:
Mechanisms of Ageing and Development. 93:145-156
MRL/Mp +/+ (MRL/+) mice, not bearing the lpr gene, are known to have age-related autoimmune lesions in several organs such as pancreas, salivary and lacrimal glands at 30-weeks-old or more. In this study, MRL/+ mice were ovariectomized at 4-weeks-old
Publikováno v:
Cellular Immunology. 170:54-62
To elucidate the mechanism of development in autoimmune lacrimal gland disease, we analyzed different aspects of autoimmune dacryoadenitis in a newly established mouse model for primary Sjögren's syndrome, focusing on the local expressions of cytoki
Publikováno v:
Autoimmunity. 23:269-277
In an attempt to elucidate the mechanism of development of organ-specific autoimmune lesions resembling human Sjögren's syndrome of MRL/lpr mice, we have analyzed local cytokine gene expressions and organ-specific autoantibody production in vivo. We
Autor:
Yoshio Hayashi, Koji Harada, Masato Okamoto, Mitsunobu Sato, Yoshiaki Yura, Hideo Yoshida, Masayuki Azuma, Tokuyuki Yuuki, Jun Kusaka, Hironori Hamano
Publikováno v:
Oral Medicine & Pathology. 1:97-102
Basal cell adenocarcinoma is a relatively recently described rare type of malignant salivary gland tumor found most often in the parotid gland. We present a case report of minor salivary gland basal cell adenocarcinoma arising in the mandible. Histol
Autor:
Naozumi Ishimaru, Sinji Tamada, Hironori Hamano, Yoshio Hayashi, Kumiko Yanagi, Norio Haneji, Mitsunobu Sato, Hideo Yoshida
Publikováno v:
Oral Medicine & Pathology. 1:33-37
Primary malignant melanoma in situ of the lower lip is exceedingly rare. Two Japanese patients with malignant melanoma in situ in the mucous membrane of the lower lip are presented. One case was an 31-year-old female, and the other was an 14-year-old
Publikováno v:
Oral Medicine & Pathology. 1:49-52
The light microscopic, electron microscopic and immunohistochemical features of a large cell undifferentiated parotid gland carcinoma are presented. The tumor was composed predominantly of undifferentiated, polygonal large cells with focally admixed
Immunopathological Analysis of Mucosal Melanocyte Distribution in the Human Lower Lip of the Elderly
Publikováno v:
Pathobiology. 64:156-160
Mucosal melanocyte distribution in the human lower lip was analyzed immunopathologically using a wide selection of 195 surgical specimens. An age-related increase of mucosal melanocyte distribution was observed in the human lower lip by Fontana-Masso
Publikováno v:
Pathobiology. 64:255-261
Stimulation of a cultured human salivary gland (HSG) cell line by interferon (IFN)-gamma leads to HLA-DR gene expression concomitant with inflammatory cytokine genes such as IL-1 beta, tumor necrosis factor (TNF)-alpha, and IL-6 in vitro. IFN-gamma-i
Publikováno v:
European Journal of Immunology. 24:2826-2831
We describe the successful transfer of murine Sjögren's syndrome-like autoimmune lesions from MRL/lpr mice (H-2k) to severe combined immunodeficiency (SCID) mice (H-2d) and prevention of lesions by anti-CD4 and -T cell receptor V beta 8 antibody tre
Publikováno v:
Pathology International. 44:559-568
Sjögren's syndrome in humans is a chronic inflammatory disease with a presumed autoimmune etiology of the exocrine organs, involving in particular the salivary and lacrimal glands. The pathogenesis of this syndrome remains unclear, but the majority