Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Hironori Aramaki"'
Publikováno v:
Current Issues in Molecular Biology, Vol 44, Iss 9, Pp 3849-3858 (2022)
Experimental evidence accumulated by our research group and others strongly suggests that (–)-xanthatin, a xanthanolide sesquiterpene lactone, exhibits anti-proliferative effects on human breast cancer cells (in vitro) as well as anti-tumor effects
Externí odkaz:
https://doaj.org/article/60298897216a4f5d92b938d598bd9186
Autor:
Naoya Matsunaga, Eriko Ikeda, Keisuke Kakimoto, Miyako Watanabe, Naoya Shindo, Akito Tsuruta, Hisako Ikeyama, Kengo Hamamura, Kazuhiro Higashi, Tomohiro Yamashita, Hideaki Kondo, Yuya Yoshida, Masaki Matsuda, Takashi Ogino, Kazutaka Tokushige, Kazufumi Itcho, Yoko Furuichi, Takaharu Nakao, Kaori Yasuda, Atsushi Doi, Toshiaki Amamoto, Hironori Aramaki, Makoto Tsuda, Kazuhide Inoue, Akio Ojida, Satoru Koyanagi, Shigehiro Ohdo
Publikováno v:
EBioMedicine, Vol 13, Iss C, Pp 262-273 (2016)
Chronic kidney disease (CKD) is a global health problem, and novel therapies to treat CKD are urgently needed. Here, we show that inhibition of G0/G1 switch 2 (G0s2) ameliorates renal inflammation in a mouse model of CKD. Renal expression of chemokin
Externí odkaz:
https://doaj.org/article/78a7228c8a9c43ea90380dcc86ba6101
Autor:
Takanori Akagi, Tatsuo Fukagawa, Yuki Kage, Hideto To, Naoya Matsunaga, Satoru Koyanagi, Akiko Uchida, Asuka Fujii, Hideo Iba, Toshimichi Ikemura, Hironori Aramaki, Shun Higuchi, Shigehiro Ohdo
Publikováno v:
Journal of Pharmacological Sciences, Vol 109, Iss 2, Pp 265-274 (2009)
In clinical practice, glucocorticoids are often used with the aim of modulating the efficacy and toxicity of chemotherapeutic agents. However, how glucocorticoids modulate the pharmacological action of chemotherapeutic agents remains to be clarified.
Externí odkaz:
https://doaj.org/article/888af42436c74d4fa69998ae27429b2c
Autor:
Atsushi Yamauchi, Takanobu Ichimiya, Kouichi Inoue, Yukie Taguchi, Naoya Matsunaga, Satoru Koyanagi, Tatsuo Fukagawa, Hironori Aramaki, Shun Higuchi, Shigehiro Ohdo
Publikováno v:
Journal of Pharmacological Sciences, Vol 99, Iss 4, Pp 335-341 (2005)
The role of the susceptibility of cells and the pharmacokinetics of MTX on the time-dependent change of methotrexate (MTX) pharmacologic action in HL-60 (human leukemia cell) was investigated from the viewpoints of the rhythm of DNA synthesis. The hi
Externí odkaz:
https://doaj.org/article/7c8e079197ba438fa37974d1988b3fc9
Publikováno v:
Nanoscale. 14:13315-13323
The chemical ratchet, a mechanism indifferent to detailed balance, is evidenced by a single-molecule experiment involving the binding of a bacterial repressor to its operator.
Publikováno v:
Forensic Toxicology.
Publikováno v:
Forensic toxicology.
The effects of extended ΔMCF-7 cells were treated with ΔΔΔ
Publikováno v:
Current issues in molecular biology. 44(9)
Experimental evidence accumulated by our research group and others strongly suggests that (–)-xanthatin, a xanthanolide sesquiterpene lactone, exhibits anti-proliferative effects on human breast cancer cells (in vitro) as well as anti-tumor effects
Publikováno v:
Archives of Biochemistry and Biophysics. 662:219-225
Peroxisome proliferator-activated receptors (PPARs) are a family of ligand-activated nuclear transcription factors, with three characterized subtypes: PPARα, PPARβ/δ, and PPARγ. The biological correlation between the two PPAR subtypes PPARα and
Autor:
Shuso Takeda, Hiroyuki Okazaki, Hironori Aramaki, Masufumi Takiguchi, Koichi Haraguchi, Ramu Mizunoe, Yukimi Takemoto, Masayo Hirao-Suzuki, Kazuhito Watanabe
Publikováno v:
The Journal of Toxicological Sciences. 43:321-327
Bisphenol AF (BPAF) is now recognized as one of the replacements for bisphenol A (BPA). Although considerable experimental evidence suggests that BPA is an endocrine-disrupting chemical, the toxicological profile of BPAF has been investigated in less