Zobrazeno 1 - 10
of 145
pro vyhledávání: '"Hironori Adachi"'
Publikováno v:
Bio-Protocol, Vol 14, Iss 9 (2024)
Pseudouridine (Ψ), the most prevalent modified base in cellular RNAs, has been mapped to numerous sites not only in rRNAs, tRNAs, and snRNAs but also mRNAs. Although there have been multiple techniques to identify Ψs, due to the recent development
Externí odkaz:
https://doaj.org/article/5d041d3259e1432691c7273bcea9c467
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
The current COVID-19 pandemic is a massive source of global disruption, having led so far to two hundred and fifty million COVID-19 cases and almost five million deaths worldwide. It was recognized in the beginning that only an effective vaccine coul
Externí odkaz:
https://doaj.org/article/fb6a4596b2f94b4cbe9d7cc377d7a8b6
Publikováno v:
Biochemical Journal; Jan2024, Vol. 481 Issue 1, p1-16, 16p
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Small nuclear RNAs (snRNAs) are critical components of the spliceosome that catalyze the splicing of pre-mRNA. snRNAs are each complexed with many proteins to form RNA-protein complexes, termed as small nuclear ribonucleoproteins (snRNPs), in the cel
Externí odkaz:
https://doaj.org/article/33c123b984a742129674da2e749645dd
Publikováno v:
Biomedicines, Vol 9, Iss 5, p 550 (2021)
Therapeutic oligonucleotides interact with a target RNA via Watson-Crick complementarity, affecting RNA-processing reactions such as mRNA degradation, pre-mRNA splicing, or mRNA translation. Since they were proposed decades ago, several have been app
Externí odkaz:
https://doaj.org/article/572256d2474b42de9af59d6f117e7179
Publikováno v:
Biology Open, Vol 6, Iss 9, Pp 1342-1354 (2017)
Many ribonucleoproteins (RNPs), which are comprised of noncoding RNA and associated proteins, are involved in essential cellular processes such as translation and pre-mRNA splicing. One class of RNP is the small Cajal body-specific RNP (scaRNP), whic
Externí odkaz:
https://doaj.org/article/42b851a613c3450d98e3c4b07a3c6f17
Publikováno v:
Methods in Molecular Biology ISBN: 9781071631904
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fab01df71dd328c19eb2f69566be3242
https://doi.org/10.1007/978-1-0716-3191-1_14
https://doi.org/10.1007/978-1-0716-3191-1_14
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 12, p 4394 (2020)
Nonsense mutations often result from single nucleotide substitutions that change a sense codon (coding for an amino acid) to a nonsense or premature termination codon (PTC) within the coding region of a gene. The impact of nonsense mutations is two-f
Externí odkaz:
https://doaj.org/article/399148fb0a5a40f59dc7f75b85360b7c
Autor:
Hironori Adachi, Yi-Tao Yu
Publikováno v:
RNA. 26:1247-1256
We have previously shown that when the uridine of a stop codon (UAA, UAG, or UGA) is pseudouridylated, the ribosome reads through the modified stop codon. However, it is not clear as to whether or not the pseudouridine (Ψ)-mediated readthrough is de
Autor:
Mitsunori Nasu, Hiroshi Yanai, Naoki Hirayama, Hironori Adachi, Yu Kakizawa, Yuto Shirase, Hiromichi Nishiyama, Teppei Kawamoto, Junji Inukai, Takenao Shinohara, Hirotoshi Hayashida, Masahiro Watanabe
Publikováno v:
SSRN Electronic Journal.