Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Hironori, Mitsuyoshi"'
Autor:
Hiroki Ishikawa, Toshiaki Nakashima, Koji Inaba, Hironori Mitsuyoshi, Yoshiki Nakajima, Yoshikuni Sakamoto, Takeshi Okanoue, Kei Kashima, Yoshiteru Seo
Publikováno v:
Journal of Lipid Research, Vol 40, Iss 10, Pp 1920-1924 (1999)
Biliary bile acids, coexisting with phospholipid and cholesterol, are partly conjugated with taurine. In the present report we show that total and taurine-conjugated bile acids in bile can be simultaneously and quantitatively measured by high-resolut
Externí odkaz:
https://doaj.org/article/550b392cd112412d823337aa207fc0b1
Autor:
Hironori Mitsuyoshi, Kohichiroh Yasui, Kanji Yamaguchi, Masahito Minami, Takeshi Okanoue, Yoshito Itoh
Publikováno v:
International Journal of Hepatology, Vol 2013 (2013)
Aim. Chronic hepatitis C (CHepC) is frequently associated with hepatic iron overload, yet mechanisms underlying iron-induced liver injury have not been elucidated. We examined the significance of iron deposition in hepatocytes (HC) and reticuloendoth
Externí odkaz:
https://doaj.org/article/8157c505324d48efa9a0c0f6221a96b5
Autor:
Akira Okajima, Hidetaka Takashima, Hiroyuki Kimura, Toshihide Shima, Yo Takaharu, Masayasu Jo, Yasuyuki Nagao, Michihisa Moriguchi, Yoshito Itoh, Aya Takahashi, Hironori Mitsuyoshi, Hiroki Ishikawa, Akira Muramatsu, Hideki Fujii, Yasuhide Mitsumoto, Naomi Yoshinami, Hiroshi Ishiba, Masahiro Arai, Takeshi Okanoue, Atsushi Umemura, Tasuku Hara, Kanji Yamaguchi, Taichiro Nishikawa, Atsuhiro Morita, Tomoki Nakajima, Yuya Seko
Publikováno v:
Cancers
Volume 12
Issue 3
Cancers, Vol 12, Iss 3, p 754 (2020)
Volume 12
Issue 3
Cancers, Vol 12, Iss 3, p 754 (2020)
We investigated the association between early tumor shrinkage (ETS) and treatment outcome in patients with hepatocellular carcinoma treated with lenvatinib (LEN). A retrospective analysis was performed in 104 patients. ETS was defined as tumor shrink
Autor:
Osamu Dohi, Kohichiroh Yasui, Tomoko Kitaichi, Kei Terasaki, Kanji Yamaguchi, Yoshio Sumida, Nobuhisa Yamada, Naoto Iwai, Yoshito Itoh, Hironori Mitsuyoshi, Atsushi Umemura, Yuji Naito, Taichiro Nishikawa, Yasuyuki Gen, Yoh Zen, Michihisa Moriguchi, Akira Tomie
Publikováno v:
Human Pathology. 62:134-140
Disrupted cell polarity is a feature of epithelial cancers. The partitioning defective 3 (PAR-3) protein, a key component of the PAR complex that regulates the polarization of cells, is involved in tight junction formation at epithelial cell-cell con
Autor:
Masahito Minami, Hironori Mitsuyoshi, Hiroshi Ishiba, Kohichiroh Yasui, Akira Okajima, Yoshito Itoh, Michihisa Moriguchi, Tasuku Hara, Yuya Seko, Hiroyoshi Taketani, Atsushi Umemura, Kanji Yamaguchi, Taichiro Nishikawa
Publikováno v:
Hepatology Research. 47:1459-1468
Aim To examine the role of nucleotide binding oligomerization domain-like receptor family pyrin domain-containing 3 (NLRP3) inflammasomes in the development of non-alcoholic fatty liver disease (NAFLD). Methods Levels of mRNAs encoding NLRP3, apoptos
Autor:
Hiroki Ishikawa, Naomi Yoshinami, Hironori Mitsuyoshi, Masayasu Jo, Akira Okajima, Atsuhiro Morita, Atsushi Umemura, Hidetaka Takashima, Toshihide Shima, Kanji Yamaguchi, Yasuhide Mitsumoto, Masahiro Arai, Aya Takahashi, Tomoki Nakajima, Tasuku Hara, Taichiro Nishikawa, Michihisa Moriguchi, Hideki Fujii, Hiroshi Ishiba, Yuya Seko, Hiroyuki Kimura, Takaharu Yo, Yasuyuki Nagao, Yoshito Itoh, Akira Muramatsu
Publikováno v:
Anticancer research. 39(9)
Background Factors associated with response to lenvatinib have not been clarified in patients with hepatocellular carcinoma (HCC). Patients and methods This study retrospectively analyzed 50 patients treated with lenvatinib as first-line therapy betw
Autor:
Atsushi Umemura, Yoshio Sumida, Yuya Seko, Akira Okajima, Kohichiroh Yasui, Taichiro Nishikawa, Hiroshi Ishiba, Takeshi Nishimura, Kanji Yamaguchi, Hiroyoshi Taketani, Hironori Mitsuyoshi, Masahito Minami, Michihisa Moriguchi, Tasuku Hara, Yoshito Itoh
Publikováno v:
Hepatology Research. 47:721-730
Aim Platelet count and liver stiffness measurement (LSM) using transient elastography could identify significant fibrosis in patients with nonalcoholic fatty liver disease (NAFLD). We constructed a novel index combining LSM with platelet count for st
Autor:
Hironori Mitsuyoshi, Kohichiroh Yasui, Yoshio Sumida, Akira Okajima, Atsushi Umemura, Muhei Tanaka, Seita Kataoka, Hiroyoshi Taketani, Kanji Yamaguchi, Michihisa Moriguchi, Satoshi Akabame, Hiroshi Ishiba, Taichiro Nishikawa, Ki-ichiro Tomiyasu, Tasuku Hara, Masaaki Kuroda, Yuya Seko, Masahiro Arai, Yoshito Itoh
Publikováno v:
Hepatology Research. 46:1107-1117
Aims Cardiovascular events are the leading cause of death among patients with non-alcoholic fatty liver disease (NAFLD), but their relationship remains unclear. This study examined the association between coronary atherosclerosis and liver fibrosis,
Autor:
Kohichiroh Yasui, Shinji Tanaka, Yasuyuki Gen, Mio Endo, Yoshio Sumida, Taichiro Nishikawa, Hironori Mitsuyoshi, Akira Tomie, Chika Konishi, Michihisa Moriguchi, Nobuhisa Yamada, Naoto Iwai, Shigeki Arii, Kanji Yamaguchi, Yoshito Itoh, Osamu Dohi, Tomoko Kitaichi
Publikováno v:
Cancer Science
EVI1 (ecotropic viral integration site 1) is one of the most aggressive oncogenes associated with myeloid leukemia. We investigated DNA copy number aberrations in human hepatocellular carcinoma (HCC) cell lines using a high-density oligonucleotide mi
Autor:
Michihisa Moriguchi, Tasuku Hara, Kohichiroh Yasui, Taichiroh Nishikawa, Hironori Mitsuyoshi, Yoshio Sumida, Hiroyoshi Taketani, Hiroshi Ishiba, Akira Okajima, Masahito Minami, Kanji Yamaguchi, Hideki Fujii, Yuya Seko, Yoshito Itoh, Takeshi Nishimura
Publikováno v:
Hepatology Research. 45:E156-E160
A 56-year-old male patient with chronic hepatitis C was treated with pegylated interferon (PEG IFN)-α-2b and ribavirin (RBV) for 72 weeks in 2006. The patient achieved an early virological response (EVR); however, hepatitis C relapsed 12 weeks after