Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Hironobu Umakoshi"'
Autor:
Norifusa Iwahashi, Hironobu Umakoshi, Masamichi Fujita, Tazuru Fukumoto, Tatsuki Ogasawara, Maki Yokomoto-Umakoshi, Hiroki Kaneko, Hiroshi Nakao, Namiko Kawamura, Naohiro Uchida, Yayoi Matsuda, Ryuichi Sakamoto, Masahide Seki, Yutaka Suzuki, Kohta Nakatani, Yoshihiro Izumi, Takeshi Bamba, Yoshinao Oda, Yoshihiro Ogawa
Publikováno v:
Molecular Metabolism, Vol 84, Iss , Pp 101954- (2024)
Objective: The human adrenal cortex comprises three functionally and structurally distinct layers that produce layer-specific steroid hormones. With aging, the human adrenal cortex undergoes functional and structural alteration or “adrenal aging”
Externí odkaz:
https://doaj.org/article/5088c195552d4ef3abb80bf8c93f2597
Autor:
Kohta Nakatani, Yoshihiro Izumi, Hironobu Umakoshi, Maki Yokomoto-Umakoshi, Tomoko Nakaji, Hiroki Kaneko, Hiroshi Nakao, Yoshihiro Ogawa, Kazutaka Ikeda, Takeshi Bamba
Publikováno v:
Journal of Lipid Research, Vol 65, Iss 1, Pp 100492- (2024)
Quantitative information on blood metabolites can be used in developing advanced medical strategies such as early detection and prevention of disease. Monitoring bioactive lipids such as steroids, bile acids, and PUFA metabolites could be a valuable
Externí odkaz:
https://doaj.org/article/112f82abfea747e5bf537e56184becf3
Autor:
Hiroki Kaneko, Hironobu Umakoshi, Masatoshi Ogata, Norio Wada, Takamasa Ichijo, Shohei Sakamoto, Tetsuhiro Watanabe, Yuki Ishihara, Tetsuya Tagami, Norifusa Iwahashi, Tazuru Fukumoto, Eriko Terada, Shunsuke Katsuhara, Maki Yokomoto-Umakoshi, Yayoi Matsuda, Ryuichi Sakamoto, Yoshihiro Ogawa
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract Unilateral subtype of primary aldosteronism (PA) is a common surgically curable form of endocrine hypertension. However, more than half of the patients with PA who undergo unilateral adrenalectomy suffer from persistent hypertension, which m
Externí odkaz:
https://doaj.org/article/ae07c41932c74d00955ddcf26ec607ef
Autor:
Rikako Sagara, Tomoaki Inoue, Noriyuki Sonoda, Chieko Yano, Misato Motoya, Hironobu Umakoshi, Ryuichi Sakamoto, Yoshihiro Ogawa
Publikováno v:
Journal of Diabetes Investigation, Vol 13, Iss 2, Pp 344-350 (2022)
Abstract Aims/Introduction Diabetes mellitus is a major risk factor for the development of cardiovascular diseases. Heart failure with preserved ejection fraction is characterized by left ventricular diastolic dysfunction (LVDD). It has been reported
Externí odkaz:
https://doaj.org/article/4b24e60fd5a749b0a521c801a2f068fc
Autor:
Chieko Yano, Maki Yokomoto-Umakoshi, Masamichi Fujita, Hironobu Umakoshi, Seiichi Yano, Norifusa Iwahashi, Shunsuke Katsuhara, Hiroki Kaneko, Masatoshi Ogata, Tazuru Fukumoto, Eriko Terada, Yayoi Matsuda, Ryuichi Sakamoto, Yoshihiro Ogawa
Publikováno v:
Bone Reports, Vol 17, Iss , Pp 101610- (2022)
Purpose: Bone and vascular diseases are considered to share pathogenic mechanisms. Excess glucocorticoids, key regulators of cardiovascular and metabolic homeostasis, may promote both diseases simultaneously. We used endogenous Cushing's syndrome (CS
Externí odkaz:
https://doaj.org/article/5cbbc11faf224527a29ccee74c7cb755
Autor:
Toru Masuda, Shojiro Haji, Yasuhiro Nakashima, Mariko Tsuda, Daisaku Kimura, Akiko Takamatsu, Norifusa Iwahashi, Hironobu Umakoshi, Motoaki Shiratsuchi, Chie Kikutake, Mikita Suyama, Yasuyuki Ohkawa, Yoshihiro Ogawa
Publikováno v:
iScience, Vol 25, Iss 8, Pp 104781- (2022)
Summary: Despite recent therapeutic advances for multiple myeloma (MM), relapse is very common. Here, we conducted longitudinal single-cell transcriptome sequencing (scRNA-seq) of MM cells from a patient with relapsed MM, treated with multiple anti-m
Externí odkaz:
https://doaj.org/article/f53f5722df624e71b12ddf6fc9cdbc8e
Autor:
Hiroki Kaneko, Hironobu Umakoshi, Masatoshi Ogata, Norio Wada, Norifusa Iwahashi, Tazuru Fukumoto, Maki Yokomoto-Umakoshi, Yui Nakano, Yayoi Matsuda, Takashi Miyazawa, Ryuichi Sakamoto, Yoshihiro Ogawa
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Primary aldosteronism (PA) is associated with an increased risk of cardiometabolic diseases, especially in unilateral subtype. Despite its high prevalence, the case detection rate of PA is limited, partly because of no clinical models availa
Externí odkaz:
https://doaj.org/article/5f551589dde84025ab817db2193bc766
Autor:
Norifusa Iwahashi, Hironobu Umakoshi, Masatoshi Ogata, Tazuru Fukumoto, Hiroki Kaneko, Eriko Terada, Shunsuke Katsuhara, Naohiro Uchida, Katsuhiko Sasaki, Maki Yokomoto-Umakoshi, Yayoi Matsuda, Ryuichi Sakamoto, Yoshihiro Ogawa
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Whole transcriptome profiling is a promising technique in adrenal studies; however, whole transcriptome profiling of adrenal disease using formalin-fixed paraffin-embedded (FFPE) samples has to be further explored. The aim of this study was to evalua
Externí odkaz:
https://doaj.org/article/26c01cd022f74660b5f18ef080dd8da4
Autor:
Masatoshi Murakami, Nao Fujimori, Kohei Nakata, Masafumi Nakamura, Shinichi Hashimoto, Hiroshi Kurahara, Kazuyoshi Nishihara, Toshiya Abe, Shunpei Hashigo, Naotaka Kugiyama, Eisuke Ozawa, Kazuhisa Okamoto, Yusuke Ishida, Keiichi Okano, Ryo Takaki, Yutaka Shimamatsu, Tetsuhide Ito, Masami Miki, Noriko Oza, Daisuke Yamaguchi, Hirofumi Yamamoto, Hironobu Takedomi, Ken Kawabe, Tetsuro Akashi, Koichi Miyahara, Jiro Ohuchida, Yasuhiro Ogura, Yohei Nakashima, Toshiharu Ueki, Kousei Ishigami, Hironobu Umakoshi, Keijiro Ueda, Takamasa Oono, Yoshihiro Ogawa
Publikováno v:
Journal of Gastroenterology. 58:586-597
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a35b58624b75d83ecfedd965ff7f5b2f
https://doi.org/10.1007/s00535-023-01987-8
https://doi.org/10.1007/s00535-023-01987-8
Autor:
Hiroki Kaneko, Hironobu Umakoshi, Tazuru Fukumoto, Norio Wada, Takamasa Ichijo, Shohei Sakamoto, Tetsuhiro Watanabe, Yuki Ishihara, Tetsuya Tagami, Masatoshi Ogata, Norifusa Iwahashi, Maki Yokomoto‐Umakoshi, Yayoi Matsuda, Ryuichi Sakamoto, Yoshihiro Ogawa
Publikováno v:
Clinical Endocrinology. 98:473-480
The clinical practice guideline for primary aldosteronism (PA) places a high value on confirmatory tests to sparing patients with false-positive results in case detection from undergoing adrenal venous sampling (AVS). However, it is unclear whether m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70f9217d23b7d23210c42856147972ee
https://doi.org/10.1111/cen.14854
https://doi.org/10.1111/cen.14854