Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Hironobu Nitanai"'
Autor:
Kenji Namba, Masami Ohtsuka, Yoshihiro Yokomizo, Hironobu Nitanai, Kazuki Hoshino, Makoto Takemura, Ving J. Lee, Kiyoshi Nakayama, Jason Z. Zhang, Yoshida Kenichi, William J. Watkins, Hiroko Kanda
Publikováno v:
Bioorganic & Medicinal Chemistry. 14:8506-8518
A series of 4-oxo-4H-pyrido[1,2-a]pyrimidine derivatives, derivatized at the 2-position with aromatic substituents, were synthesized by the Suzuki cross-coupling method and evaluated for their ability to potentiate the activity of the fluoroquinolone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::facb25021fe9b43c48a8e2bae278cf1e
https://doi.org/10.1016/j.bmc.2006.08.037
https://doi.org/10.1016/j.bmc.2006.08.037
Requirement of the Pseudomonas aeruginosa tonB Gene for High-Affinity Iron Acquisition and Infection
Publikováno v:
Infection and Immunity. 68:4498-4504
To investigate the contribution of the TonB protein to high-affinity iron acquisition in Pseudomonas aeruginosa , we constructed tonB -inactivated mutants from strain PAO1 and its derivative deficient in producing the siderophores pyoverdin and pyoch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e3d2550ce39270fbad3c671011621eb
https://doi.org/10.1128/iai.68.8.4498-4504.2000
https://doi.org/10.1128/iai.68.8.4498-4504.2000
Publikováno v:
Infection and Immunity. 68:1834-1839
Pseudomonas aeruginosa produces siderophores, pyoverdin and pyochelin, for high-affinity iron uptake. To investigate their contribution to P. aeruginosa infections, we constructed allelic exchange mutants from strain PAO1 which were deficient in prod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eaa4aec1aabb041b51efc713987fc64b
https://doi.org/10.1128/iai.68.4.1834-1839.2000
https://doi.org/10.1128/iai.68.4.1834-1839.2000
Autor:
Toshifumi Tanabe, Yoshiyuki Hashimoto, Hironobu Nitanai, Shinya Suzuki, Toshinori Agatsuma, Kazunori Kato
Publikováno v:
Japanese Journal of Cancer Research : Gann
The therapeutic effect of a combined modality of lymphokine-activated killer (LAK) cells and tumor necrosis factor alpha (TNF alpha) on MBL-2 tumor in C57BL/6 mice was studied. Murine LAK cells induced from splenocytes by interleukin 2 (IL2) could ly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d71179ce253c1d86261c04eee34f583b
https://doi.org/10.1111/j.1349-7006.1991.tb01871.x
https://doi.org/10.1111/j.1349-7006.1991.tb01871.x
Autor:
Kazuki Hoshino, Yoshida Kenichi, William J. Watkins, Atsunobu Sakamoto, Masami Ohtsuka, Kumi Yoshida, Yoshihiro Yokomizo, Yuichiro Imamura, Kiyoshi Nakayama, Hironobu Nitanai, Hiroko Kanda, Makoto Takemura, Ving J. Lee, Jason Z. Zhang, Noriko Kuru, Kenji Namba
Publikováno v:
Bioorganicmedicinal chemistry. 15(22)
A series of 4-oxo-4 H -pyrido[1,2- a ]pyrimidine derivatives, substituted at the 2-position with piperidines bearing quaternary ammonium salt side chains, were synthesized and evaluated for their ability to potentiate the activity of the fluoroquinol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be657d6aa5504b86ff1ce674c0790dbe
https://pubmed.ncbi.nlm.nih.gov/17869116
https://pubmed.ncbi.nlm.nih.gov/17869116
Publikováno v:
Microbiology and immunology. 43(9)
A strain of Streptococcus pneumoniae, when inoculated intranasally in 2 microl of suspension into BALB/c mice preinfected with influenza virus, colonized first in the nose, and several days thereafter also colonized significantly in the trachea and l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::711863ec3d2385887076bcbee01901ab
https://pubmed.ncbi.nlm.nih.gov/10553684
https://pubmed.ncbi.nlm.nih.gov/10553684
Publikováno v:
Vaccine. 15(4)
The response of megakaryocytes and cytokines to the administration of romurtide, a synthetic muramyl dipeptide derivative, was investigated in monkeys with myelosuppression by carboplatin-treatment. Romurtide increased the number of megakaryocytes an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::108639f53ca108d17a3c5389ec2c18e2
https://pubmed.ncbi.nlm.nih.gov/9141212
https://pubmed.ncbi.nlm.nih.gov/9141212
Publikováno v:
Vaccine. 14(14)
We investigated the therapeutic effects of romurtide, a synthetic muramyl dipeptide derivative, on experimental thrombocytopenia induced by carboplatin in cynomolgus monkeys. A prolonged thrombocytopenia due to a severe myelosuppression was induced b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0e99bb9fe5fa95e9e4b4e605969ef48
https://pubmed.ncbi.nlm.nih.gov/9004440
https://pubmed.ncbi.nlm.nih.gov/9004440
Publikováno v:
International journal of cancer. 46(6)
The effect of recombinant human tumor necrosis factor-alpha (rhTNF-alpha) on anti-tumor activity of adriamycin entrapped in small unilamellar liposomes (ADM-Lip) has been studied using BALB/c mice bearing subdermal Meth-A fibrosarcoma. Accumulation o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d7c577b8be8b9e5364521d37ebb3d4b
https://pubmed.ncbi.nlm.nih.gov/2249897
https://pubmed.ncbi.nlm.nih.gov/2249897