Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Hironobu Nakayama"'
Autor:
Michiyo Okamoto, Azusa Takahashi-Nakaguchi, Kengo Tejima, Kaname Sasamoto, Masashi Yamaguchi, Toshihiro Aoyama, Minoru Nagi, Kohichi Tanabe, Yoshitsugu Miyazaki, Hironobu Nakayama, Chihiro Sasakawa, Susumu Kajiwara, Alistair J. P. Brown, Miguel C. Teixeira, Hiroji Chibana
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
The uptake of cholesterol from the host is closely linked to the proliferation of pathogenic fungi and protozoa during infection. For some pathogenic fungi, cholesterol uptake is an important strategy for decreasing susceptibility to antifungals that
Externí odkaz:
https://doaj.org/article/032d13171c144ec89662613b0415c996
Autor:
Asuka Minematsu, Taiga Miyazaki, Shintaro Shimamura, Hiroshi Nishikawa, Hironobu Nakayama, Takahiro Takazono, Tomomi Saijo, Kazuko Yamamoto, Yoshifumi Imamura, Katsunori Yanagihara, Shigeru Kohno, Hiroshi Mukae, Koichi Izumikawa
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0210883 (2019)
Vacuolar proton-translocating ATPase (V-ATPase) is located in fungal vacuolar membranes. It is involved in multiple cellular processes, including the maintenance of intracellular ion homeostasis by maintaining acidic pH within the cell. The importanc
Externí odkaz:
https://doaj.org/article/cafdb2c93dec49be8f684b60c1b47651
Autor:
Yohsuke Nagayoshi, Taiga Miyazaki, Shintaro Shimamura, Hironobu Nakayama, Asuka Minematsu, Shunsuke Yamauchi, Takahiro Takazono, Shigeki Nakamura, Katsunori Yanagihara, Shigeru Kohno, Hiroshi Mukae, Koichi Izumikawa
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0180990 (2017)
The pathogenic fungus Candida glabrata is often resistant to azole antifungal agents. Drug efflux through azole transporters, such as Cdr1 and Cdr2, is a key mechanism of azole resistance and these genes are under the control of the transcription fac
Externí odkaz:
https://doaj.org/article/d3768d1fb85b4798983fdf600151d57f
Autor:
Minoru Nagi, Koichi Tanabe, Kazuko Tanaka, Keigo Ueno, Hironobu Nakayama, Jun Ishikawa, Masahiro Abe, Satoshi Yamagoe, Takashi Umeyama, Shigeki Nakamura, Motoyuki Sugai, Kevin C. Hazen, Yoshitsugu Miyazaki
Publikováno v:
JAC-Antimicrobial Resistance. 4
Background Candida glabrata is an emerging fungal pathogen in immune-compromised hosts. Previously undetected C. glabrata isolates were successfully recovered from clinical specimens by adding sterols to the growth medium. The clinical isolates are u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07ea7c2466e028ef281d731d2d21730e
https://doi.org/10.1093/jacamr/dlac018
https://doi.org/10.1093/jacamr/dlac018
Autor:
Michiyo, Okamoto, Azusa, Takahashi-Nakaguchi, Kengo, Tejima, Kaname, Sasamoto, Masashi, Yamaguchi, Toshihiro, Aoyama, Minoru, Nagi, Kohichi, Tanabe, Yoshitsugu, Miyazaki, Hironobu, Nakayama, Chihiro, Sasakawa, Susumu, Kajiwara, Alistair J P, Brown, Miguel C, Teixeira, Hiroji, Chibana
Publikováno v:
Frontiers in cell and developmental biology. 10
The uptake of cholesterol from the host is closely linked to the proliferation of pathogenic fungi and protozoa during infection. For some pathogenic fungi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7bb1cd0a2d7397060a1b88eddbdbbb13
https://pubmed.ncbi.nlm.nih.gov/35399500
https://pubmed.ncbi.nlm.nih.gov/35399500
Autor:
Minoru, Nagi, Koichi, Tanabe, Kazuko, Tanaka, Keigo, Ueno, Hironobu, Nakayama, Jun, Ishikawa, Masahiro, Abe, Satoshi, Yamagoe, Takashi, Umeyama, Shigeki, Nakamura, Motoyuki, Sugai, Kevin C, Hazen, Yoshitsugu, Miyazaki
Publikováno v:
JAC-antimicrobial resistance. 4(1)
This study characterizes the sterol-auxotrophicDrug susceptibility of theThe sterol-auxotrophic strains showed high-level resistance to both azoles and amphotericin B when sterols were supplied in the test medium. Additionally, the strains harbour mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ab7b9816eddb3c0f1240f7617573421e
https://pubmed.ncbi.nlm.nih.gov/35265841
https://pubmed.ncbi.nlm.nih.gov/35265841
Autor:
Hironobu Nakayama, Takahiro Oura, Susumu Kajiwara, Shun Iwatani, Noboru Iwanami, Yuimi Yamada, Satoru Hasegawa, Yusuke Nakayama
Publikováno v:
Current Genetics. 65:1251-1261
Glycosylphosphatidylinositol (GPI) is an important compound for the growth of fungi, because GPI-anchored proteins including glycosyltransferases and adhesins are involved in cell-wall integrity, adhesion, and nutrient uptake in this organism. In thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0583c8c040eaf93066eab9c42816cf68
https://doi.org/10.1007/s00294-019-00987-7
https://doi.org/10.1007/s00294-019-00987-7
Autor:
Tatsuya Inukai, Yoshiyuki Adachi, Kazuyuki Hirai, Kenta Kondo, Hiroyasu Inada, Koji Suzuki, Noriko Nagi-Miura, Naohito Ohno, Hironobu Nakayama, Tomonari Tsutsumi
Publikováno v:
Journal of vascular research. 59(3)
Background: Kawasaki Disease (KD) is associated with diffuse and systemic vasculitis of unknown aetiology and mainly affects infants and children. Intravenous immunoglobulin (IVIG) treatment reduces the risk of developing coronary aneurysms, but some
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efbe5f30343c51bf1833fe7160798bfc
https://pubmed.ncbi.nlm.nih.gov/34929700
https://pubmed.ncbi.nlm.nih.gov/34929700
Publikováno v:
PLoS Pathogens, Vol 9, Iss 1, p e1003160 (2013)
Proper protein folding in the endoplasmic reticulum (ER) is vital in all eukaryotes. When misfolded proteins accumulate in the ER lumen, the transmembrane kinase/endoribonuclease Ire1 initiates splicing of HAC1 mRNA to generate the bZIP transcription
Externí odkaz:
https://doaj.org/article/2f1061b12d0a49e1a0b08244bf84657c
Autor:
Hironobu Nakayama, Michiya Murakami, Kazuyuki Hirai, Hiroshi Komada, Naoki Ando, Atsuo Sounai
Publikováno v:
Biocontrol Science. 24:155-160
Ozonated water (OW) is presently used as a chemical disinfectant in many fields, due to its versatile antimicrobial properties. As ozone rapidly decomposes to oxygen, especially in the presence of organic matter, it is important to estimate the authe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e9086b0f3d148b0a94285f4df48cabf
https://doi.org/10.4265/bio.24.155
https://doi.org/10.4265/bio.24.155