Zobrazeno 1 - 10
of 299
pro vyhledávání: '"Hironobu, Naiki"'
Autor:
Tomohisa Yamaguchi, Tadanori Hamano, Kiyonao Sada, Rei Asano, Nicholas M. Kanaan, Hirohito Sasaki, Shu-Hui Yen, Yuki Kitazaki, Yoshinori Endo, Soichi Enomoto, Norimichi Shirafuji, Masamichi Ikawa, Osamu Yamamura, Youshi Fujita, Koji Aoki, Hironobu Naiki, Maho Morishima, Yuko Saito, Shigeo Murayama, Yasunari Nakamoto
Publikováno v:
Neurobiology of Disease, Vol 201, Iss , Pp 106656- (2024)
Spleen tyrosine kinase (Syk), a non-receptor-type tyrosine kinase, has a wide range of physiological functions. A possible role of Syk in Alzheimer's disease (AD) has been proposed. We evaluated the localization of Syk in the brains of patients with
Externí odkaz:
https://doaj.org/article/239a93f919264675ad69ceb404dfc1d2
Autor:
Naoki Takahashi, Seiji Yokoi, Hideki Kimura, Hironobu Naiki, Taiji Matsusaka, Yasuhiko Yamamoto, Kimihiko Nakatani, Kenji Kasuno, Masayuki Iwano
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Podocyte expression of fibroblast specific protein 1 (FSP1) is observed in various types of human glomerulonephritis. Considering that FSP1 is secreted extracellularly and has been shown to have multiple biological effects on distant cells,
Externí odkaz:
https://doaj.org/article/e3a72e3216734307a6daf1f6956ec468
Autor:
Satomi Hatta, Yoshihito Ichiuji, Shingo Mabu, Mauricio Kugler, Hidekata Hontani, Tadakazu Okoshi, Haruki Fuse, Takako Kawada, Shoji Kido, Yoshiaki Imamura, Hironobu Naiki, Kunihiro Inai
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Despite the dedicated research of artificial intelligence (AI) for pathological images, the construction of AI applicable to histopathological tissue subtypes, is limited by insufficient dataset collection owing to disease infrequency. Here,
Externí odkaz:
https://doaj.org/article/c621af8e71764a4898053d29b79e04fe
Autor:
Kunihiro Inai, Shohei Higuchi, Akihiro Shimada, Kyoko Hisada, Yukio Hida, Satomi Hatta, Fumihiro Kitano, Miyuki Uno, Haruka Matsukawa, Sakon Noriki, Hiromichi Iwasaki, Hironobu Naiki
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Although Sepsis-3 doesn’t require evidence of bacteremia to diagnose sepsis, clinicians often want to identify the causative pathogen at autopsy. In principle, if the blood cultures are the same at ante- and postmortem, the cause of death
Externí odkaz:
https://doaj.org/article/03f294509769428eb4f2bdfd3e64d022
Autor:
Yuki Shimamoto, Naoki Takahashi, Nagaaki Katoh, Yuki Matsui, Yusuke Mochizuki, Masanori Ito, Masahide Yazaki, Fuyuki Kametani, Kenji Kasuno, Yoshiki Sekijima, Hironobu Naiki, Masayuki Iwano
Publikováno v:
BMC Nephrology, Vol 24, Iss 1, Pp 1-8 (2023)
Abstract Background Light and heavy chain deposition disease (LHCDD) is a rare condition characterised by the deposition of immunoglobulin components in the kidneys. Similarly, Amyloidosis is also caused by the deposition of light chain and/or heavy
Externí odkaz:
https://doaj.org/article/cce1f7a819824074bbd697a34b45ff8f
Autor:
Kichitaro Nakajima, Keiichi Yamaguchi, Masahiro Noji, César Aguirre, Kensuke Ikenaka, Hideki Mochizuki, Lianjie Zhou, Hirotsugu Ogi, Toru Ito, Ichiei Narita, Fumitake Gejyo, Hironobu Naiki, Suguru Yamamoto, Yuji Goto
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Amyloid fibrils of β2-microglobulin (β2m) can cause dialysis-related amyloidosis. Here, the authors show that a decrease in serum albumin levels in long-term dialysis deteriorates the inhibitory effects of serum milieux on supersaturation-limited a
Externí odkaz:
https://doaj.org/article/d80ffdffa03b47a68ce0fdd216dda884
Publikováno v:
Renal Replacement Therapy, Vol 5, Iss 1, Pp 1-8 (2019)
Abstract We introduced criteria for the clinical diagnosis of dialysis-related amyloidosis (DRA) from the Amyloidosis Research Group study supported by a Grant-in-Aid from the Ministry of Health, Labour and Welfare of Japan. DRA exhibits various kind
Externí odkaz:
https://doaj.org/article/7d745e465374421c827ee976a59fc32e
Autor:
Yoshinori Endo, Kazuhiro Hasegawa, Ryo Nomura, Hidetaka Arishima, Ken-ichiro Kikuta, Taro Yamashita, Yasuteru Inoue, Mitsuharu Ueda, Yukio Ando, Mark R. Wilson, Tadanori Hamano, Yasunari Nakamoto, Hironobu Naiki
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-11 (2019)
Abstract Sporadic cerebral amyloid angiopathy (CAA) is characterized by cerebrovascular amyloid-β (Aβ) deposition, which leads to lobar hemorrhage and dementia. Biological molecules affecting the development of CAA have not been fully characterized
Externí odkaz:
https://doaj.org/article/698570859eab42e28b934a7f39b57efe
Autor:
Hironobu Naiki, Aina Yamaguchi, Yoshiki Sekijima, Mitsuharu Ueda, Kenichi Ohashi, Kinta Hatakeyama, Yoshihiko Ikeda, Yoshinobu Hoshii, Yukako Shintani-Domoto, Aya Miyagawa-Hayashino, Hanako Tsujikawa, Jin Endo, Tomio Arai, Yukio Ando
Publikováno v:
Amyloid. :1-6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b380fa911a68d6c79edd7786e29463f2
https://doi.org/10.1080/13506129.2023.2180334
https://doi.org/10.1080/13506129.2023.2180334
Autor:
Katsushi Tajima, Takashi Nomura, Taichi Terada, Shuhei Okuyama, Hiroaki Kumagai, Kunihiko Maeda, Shinya Ogata, Hironobu Naiki
Publikováno v:
Annals of Hematology. 102:1625-1627
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de3a747c27100e4a751fdab61161134d
https://doi.org/10.1007/s00277-023-05207-4
https://doi.org/10.1007/s00277-023-05207-4