Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Hironao Kusakari"'
Autor:
Sachi Maeda, Fumiharu Ohka, Yusuke Okuno, Kosuke Aoki, Kazuya Motomura, Kazuhito Takeuchi, Hironao Kusakari, Nobuyuki Yanagisawa, Shinya Sato, Junya Yamaguchi, Kuniaki Tanahashi, Masaki Hirano, Akira Kato, Hiroyuki Shimizu, Yotaro Kitano, Shintaro Yamazaki, Shinji Yamashita, Hideo Takeshima, Keiko Shinjo, Yutaka Kondo, Toshihiko Wakabayashi, Atsushi Natsume
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-12 (2020)
Abstract Diffuse midline glioma, H3 K27M-mutant is a lethal brain tumor located in the thalamus, brain stem, or spinal cord. H3 K27M encoded by the mutation of a histone H3 gene such as H3F3A plays a pivotal role in the tumorigenesis of this type of
Externí odkaz:
https://doaj.org/article/6022ac32f68642d68773d237f5291135
Autor:
Yutaka Kondo, Nobuyuki Yanagisawa, Yusuke Okuno, Shinji Yamashita, Yotaro Kitano, Kuniaki Tanahashi, Fumiharu Ohka, Shintaro Yamazaki, Akira Kato, Toshihiko Wakabayashi, Hideo Takeshima, Junya Yamaguchi, Kosuke Aoki, Atsushi Natsume, Sachi Maeda, Keiko Shinjo, Hiroyuki Shimizu, Hironao Kusakari, Shinya Sato, Kazuya Motomura, Kazuhito Takeuchi, Masaki Hirano
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-12 (2020)
Acta Neuropathologica Communications
Acta Neuropathologica Communications
Diffuse midline glioma, H3 K27M-mutant is a lethal brain tumor located in the thalamus, brain stem, or spinal cord. H3 K27M encoded by the mutation of a histone H3 gene such as H3F3A plays a pivotal role in the tumorigenesis of this type of glioma. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe0dca6c7a113f9d5a1cefd90ba43be8
https://doaj.org/article/6022ac32f68642d68773d237f5291135
https://doaj.org/article/6022ac32f68642d68773d237f5291135
Autor:
Maeda, Sachi, Fumiharu Ohka, Okuno, Yusuke, Aoki, Kosuke, Motomura, Kazuya, Takeuchi, Kazuhito, Hironao Kusakari, Yanagisawa, Nobuyuki, Sato, Shinya, Yamaguchi, Junya, Tanahashi, Kuniaki, Hirano, Masaki, Kato, Akira, Shimizu, Hiroyuki, Yotaro Kitano, Yamazaki, Shintaro, Yamashita, Shinji, Takeshima, Hideo, Shinjo, Keiko, Kondo, Yutaka, Wakabayashi, Toshihiko, Natsume, Atsushi
Additional file 5: Figure S5. Flowchart indicating identification of the most appropriate chromosomal structure model in case 12. Total copy number of 1q obtained by WGS (2 ≧), tumor content in tumor specimen (90.6%), BAF of SNPs obtained by WG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0977f7c4468c82588a8b11740c224089
Autor:
Maeda, Sachi, Fumiharu Ohka, Okuno, Yusuke, Aoki, Kosuke, Motomura, Kazuya, Takeuchi, Kazuhito, Hironao Kusakari, Yanagisawa, Nobuyuki, Sato, Shinya, Yamaguchi, Junya, Tanahashi, Kuniaki, Hirano, Masaki, Kato, Akira, Shimizu, Hiroyuki, Yotaro Kitano, Yamazaki, Shintaro, Yamashita, Shinji, Takeshima, Hideo, Shinjo, Keiko, Kondo, Yutaka, Wakabayashi, Toshihiko, Natsume, Atsushi
Additional file 6: Figure S6. Protein expression levels of H3 K27M and H3K27me3. Protein expression level of H3 K27M (upper) and H3K27me3 (lower) in lower VAF case (case 6) and MASI case (case 10). H3F3A wild-type gliomas (IDH1 mutated) sample was us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ae53fb9d089e287e86ef7b69722407a
Autor:
Maeda, Sachi, Fumiharu Ohka, Okuno, Yusuke, Aoki, Kosuke, Motomura, Kazuya, Takeuchi, Kazuhito, Hironao Kusakari, Yanagisawa, Nobuyuki, Sato, Shinya, Yamaguchi, Junya, Tanahashi, Kuniaki, Hirano, Masaki, Kato, Akira, Shimizu, Hiroyuki, Yotaro Kitano, Yamazaki, Shintaro, Yamashita, Shinji, Takeshima, Hideo, Shinjo, Keiko, Kondo, Yutaka, Wakabayashi, Toshihiko, Natsume, Atsushi
Additional file 1: Figure S1. Copy numbers of whole chromosomes in four MASI cases. Total copy number of whole chromosomes obtained by WGS in four MASI cases (case 5, 10, 12 and 15). Case 5, 10 and 15 were male (X: one and Y: one). Case 12 was female
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d0938dfbe774bddb1e9a5cef6b01fc2
Autor:
Maeda, Sachi, Fumiharu Ohka, Okuno, Yusuke, Aoki, Kosuke, Motomura, Kazuya, Takeuchi, Kazuhito, Hironao Kusakari, Yanagisawa, Nobuyuki, Sato, Shinya, Yamaguchi, Junya, Tanahashi, Kuniaki, Hirano, Masaki, Kato, Akira, Shimizu, Hiroyuki, Yotaro Kitano, Yamazaki, Shintaro, Yamashita, Shinji, Takeshima, Hideo, Shinjo, Keiko, Kondo, Yutaka, Wakabayashi, Toshihiko, Natsume, Atsushi
Additional file 3: Figure S3. Flowchart indicating identification of the most appropriated chromosomal structure model in case 15. Total copy number of 1q obtained by WGS (3 ≦), tumor content in tumor specimen (98.8%), BAF of SNPs obtained by W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9203124080216f813c97d625b2269678
Autor:
Maeda, Sachi, Fumiharu Ohka, Okuno, Yusuke, Aoki, Kosuke, Motomura, Kazuya, Takeuchi, Kazuhito, Hironao Kusakari, Yanagisawa, Nobuyuki, Sato, Shinya, Yamaguchi, Junya, Tanahashi, Kuniaki, Hirano, Masaki, Kato, Akira, Shimizu, Hiroyuki, Yotaro Kitano, Yamazaki, Shintaro, Yamashita, Shinji, Takeshima, Hideo, Shinjo, Keiko, Kondo, Yutaka, Wakabayashi, Toshihiko, Natsume, Atsushi
Additional file 4: Figure S4. Flowchart indicating identification of the most appropriate chromosomal structure model in case 10. Total copy number of 1q obtained by WGS (2 ≦), tumor content in tumor specimen (64.1%), BAF of SNPs obtained by WG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1ee7df92fa518cb4c3cd5d7fd906a63
Autor:
Maeda, Sachi, Fumiharu Ohka, Okuno, Yusuke, Aoki, Kosuke, Motomura, Kazuya, Takeuchi, Kazuhito, Hironao Kusakari, Yanagisawa, Nobuyuki, Sato, Shinya, Yamaguchi, Junya, Tanahashi, Kuniaki, Hirano, Masaki, Kato, Akira, Shimizu, Hiroyuki, Yotaro Kitano, Yamazaki, Shintaro, Yamashita, Shinji, Takeshima, Hideo, Shinjo, Keiko, Kondo, Yutaka, Wakabayashi, Toshihiko, Natsume, Atsushi
Additional file 2: Figure S2. Flowchart indicating identification of the most appropriated chromosomal structure model in case 5. Total copy number of 1q obtained by WGS (3 ≦), tumor content in tumor specimen (64.2%), BAF of SNPs obtained by WG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73208b52bceff83dc27ad2e6e4bb8a41