Zobrazeno 1 - 10
of 155
pro vyhledávání: '"Hironaka AIHARA"'
Autor:
Masaaki Kimura, Hiroaki Araki, Hironaka Aihara, Yasuko Karasawa, Kazuaki Kawashima, Shigeru Okuyama, Susumu Otomo, Hiroko Shimamura-Harada
Publikováno v:
General Pharmacology: The Vascular System. 22:143-150
1. 1. We examined the effects of minaprine on cerebral infarction produced by occluding of unilateral middle cerebral artery (MCA) above the rhinal fissure in stroke-prone spontaneously hypertensive rats (SHRSP). 2. 2. Oral administration of minaprin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1aadc6c6d53286b7b671d86a85e4f50
https://doi.org/10.1016/0306-3623(91)90325-z
https://doi.org/10.1016/0306-3623(91)90325-z
Publikováno v:
European Journal of Pharmacology. 178:343-350
The H2-receptor antagonistic activities and properties of IT-066 were investigated in rabbit isolated gastric mucosal cell and were compared with those of famotidine and cimetidine. IT-066 inhibited dose dependently the histamine-stimulated [14C]amin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff433001d042f8ba845dc340298c1754
https://doi.org/10.1016/0014-2999(90)90113-k
https://doi.org/10.1016/0014-2999(90)90113-k
Autor:
Katsuharu Tsuchida, Makoto Muramatsu, Katsuyoshi Kaneko, Ryuzaburo Yamazaki, Takashi Yamada, Naoyoshi Ogawa, Hironaka Aihara
Publikováno v:
Cardiovascular Drug Reviews. 8:45-55
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::456652baed385059b04e30ffd80ff51b
https://doi.org/10.1111/j.1527-3466.1990.tb00428.x
https://doi.org/10.1111/j.1527-3466.1990.tb00428.x
Publikováno v:
Neurochemistry International. 16:301-307
5-Hydroxytryptamine (serotonin, 5-HT) and 5-HT(2) receptor agonist 4-bromo-2,5-dimethoxyphenylisopropylamine (DOB) inhibited K(+)-induced [(3)H]acetylcholine ([(3)H]ACh) release from slices and crude synaptosomes of rat cerebral cortex. Minaprine [3(
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02554a7ad720648e3f51beeb75f43d9b
https://doi.org/10.1016/0197-0186(90)90106-4
https://doi.org/10.1016/0197-0186(90)90106-4
Publikováno v:
Japanese journal of pharmacology. 57(1)
3-Amino-4-[4-[4-(1-piperidinomethyl)-2-pyridyloxy]-cis-2-butenylamino]-3-cyclobutene-1, 2-dione hydrochloride (IT-066) showed a highly potent and long lasting H2-receptor blocking action in guinea pig atria. The inhibitory effect of IT-066 on the his
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87e5e243d4bedc8a591477e8a3d892d8
https://pubmed.ncbi.nlm.nih.gov/1686920
https://pubmed.ncbi.nlm.nih.gov/1686920
Effect of salvianolic acid A, a depside from roots of Salvia miltiorrhiza, on gastric H+,K(+)-ATPase
Autor:
Haruko Kijima, Susumu Otomo, Shigeru Murakami, Makoto Muramatsu, L N Li, Yoshihiko Isobe, Hironaka Aihara, C B Ai
Publikováno v:
Planta medica. 56(4)
Salvianolic acid A, a depside from the roots of Salvia miltiorrhiza, inhibited pig gastric H+,K(+)-ATPase and pNPPase with 50% inhibition values (IC50) of 5.2 x 10(-7) M and 1.7 x 10(-6) M, respectively. Kinetic studies revealed that the inhibition p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd124e36872cf04034d420e1ff8f73ac
https://pubmed.ncbi.nlm.nih.gov/2173008
https://pubmed.ncbi.nlm.nih.gov/2173008
Autor:
Masahiro Harada, Susumu Otomo, Hideo Okumura, T. Takamura, T. Kobayashi, Hironaka Aihara, Nobuo Ikekawa, Takao Yamamuro, Shohei Higuchi
Publikováno v:
Bone and mineral. 9(2)
The effect of 26,27-hexafluoro-1,25-dihydroxyvitamin D3 (F6-1,25(OH)2D3) on experimental osteoporosis in the rat induced by a combination of immobilization and ovariectomy was evaluated. F6-1,25(OH)2D3 increased the femur score and the photo-density.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a56052c8b06a3bf56b4c522ecbe64cf7
https://pubmed.ncbi.nlm.nih.gov/2350614
https://pubmed.ncbi.nlm.nih.gov/2350614
Publikováno v:
Neuropharmacology. 29(1)
2-Deoxy-D-glucose (2-DG) administered intraperitoneally, dose-dependently increased the secretion of gastric acid, and the changes were comparable with those on the activity of choline acetyltransferase (CAT) and acetylcholinesterase (AChE) in the st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc9f2d939e5e69253b8ba337d5f615a1
https://pubmed.ncbi.nlm.nih.gov/2304615
https://pubmed.ncbi.nlm.nih.gov/2304615
The antiseoretory properties of a new histamine H2-receptor antagonist, IT-066, in vitro and in vivo
Publikováno v:
European Journal of Pharmacology. 183:302-303
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d37e826c431ee4fad3614238399fd57
https://doi.org/10.1016/0014-2999(90)93159-n
https://doi.org/10.1016/0014-2999(90)93159-n
Publikováno v:
Journal of Cardiovascular Pharmacology. 18:769
We examined the calcium antagonistic action of CD-349, a dihydropyridine derivative, on goat cardiac Purkinje fibers using the two-microelectrode voltage-clamp method. CD-349 at a concentration of 10(-5) M shortened the action potential duration with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::700fe04589ac27564aa688cdd097f9f9
https://doi.org/10.1097/00005344-199111000-00016
https://doi.org/10.1097/00005344-199111000-00016