Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Hiromu Murofushi"'
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51093 (2012)
Cyclic phosphatidic acid (cPA) is a naturally occurring phospholipid mediator with a unique cyclic phosphate ring at the sn-2 and sn-3 positions of its glycerol backbone. We have previously shown that cPA significantly suppresses ischemia-induced del
Externí odkaz:
https://doaj.org/article/00bc8407c1d045f88c9bd1fbae97241a
Autor:
Seiya Tanaka, Mari Gotoh, Hiromu Murofushi, Keiko Fukasawa, Shingo Nakajima, Kimiko Murakami-Murofushi
Publikováno v:
Journal of Chromatography A. 1567:177-184
Cyclic phosphatidic acid (cPA) is a simple lipid containing a fatty acid attached at the sn-1 position and a cyclic phosphate ring structure at the sn-2 and sn-3 positions of the glycerol backbone. The pharmacological effects of cPA have been demonst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82e11e035ebd7a2dc9f0c80687d8e902
https://doi.org/10.1016/j.chroma.2018.07.010
https://doi.org/10.1016/j.chroma.2018.07.010
Publikováno v:
Brain Research. 1681:44-51
Lysophosphatidic acid (LPA) and cyclic phosphatidic acid (cPA) are one of the lipid mediators regulating cell proliferation and differentiation through the activation of LPA receptors. An LPA receptor-mediated signal is important for the development
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52610f19c20120d949b3e11f99b9773f
https://doi.org/10.1016/j.brainres.2017.12.031
https://doi.org/10.1016/j.brainres.2017.12.031
Autor:
Yasunari Takami, Takemi Enomoto, Akari Yoshimura, Motomu Akita, Masami Horikoshi, Shunichi Takeda, Katsuzumi Okumura, Tatsuo Nakayama, Shusuke Tada, Hiromu Murofushi, Masayuki Seki, Takuya Abe, Yoshifumi Hosono, Kazuto Sugimura
Publikováno v:
Journal of Biological Chemistry. 286:30504-30512
Ordered nucleosome disassembly and reassembly are required for eukaryotic DNA replication. The facilitates chromatin transcription (FACT) complex, a histone chaperone comprising Spt16 and SSRP1, is involved in DNA replication as well as transcription
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9a3b4f4e35e98abbaf6de0dc7fffb61
https://doi.org/10.1074/jbc.m111.264721
https://doi.org/10.1074/jbc.m111.264721
Autor:
Yasutaka Kakiuchi, Hiromu Murofushi, Mayuka Nakatake, Hidetoshi Arima, Yayoi Okamoto, Hirofumi Kai, Kimiko Murakami-Murofushi, Mika Oyama
Publikováno v:
CYTOLOGIA. 75:177-183
TELIN, a newly developed catalytic blocker of telomerase, was assessed for its antiproliferative activity against human tumor cells in in vitro cell culture assay. TELIN suppressed cell proliferations of several blood tumor cells with telomere shorte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3300392e24eaff2637b6d2c020f1fd3c
https://doi.org/10.1508/cytologia.75.177
https://doi.org/10.1508/cytologia.75.177
Autor:
Mika Ohyama, Toshinori Ide, Mariko Nakano, Akihiro Iwamatsu, Kazuo Kobayashi, Yukiko Shimada, Yasutaka Kakiuchi, Ei Yamada, Naoko Yano, Narie Sasaki-Higashiyama, Kazuhiko Kaji, Kimiko Murakami-Murofushi, Fumi Ikeda, Hiromu Murofushi, Sohsuke Ichikawa, Kiyoto Nishiyama, Yasuko Ogiwara
Publikováno v:
Biochemical and Biophysical Research Communications. 388:328-332
A novel telomerase-associated protein was isolated from porcine testis. The 115-kDa protein, purified with telomerase activity, was molecular cloned using human cDNA library, and identified as MOV10. The expression levels of both MOV10 mRNA and MOV10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24eb6abd8e077cbad975e53674d328e2
https://doi.org/10.1016/j.bbrc.2009.08.002
https://doi.org/10.1016/j.bbrc.2009.08.002
Autor:
Daniel L. Baker, Ryoko Tsukahara, Yuko Fujiwara, Robert Bittman, Hiromu Murofushi, Kimiko Murakami-Murofushi, Dominic Fan, Russell W. Bandle, Eunjin Koh, Gordon B. Mills, Gabor Tigyi, Susumu Kobayashi, Ayako Uchiyama, Mandi M. Murph, Kathryn R. Pigg, Hoe-Sup Byun
Publikováno v:
Journal of Biological Chemistry. 281:22786-22793
Autotaxin (ATX, nucleotide pyrophosphate/phosphodiesterase-2, NPP2) is an autocrine motility factor initially characterized from A2058 melanoma cell conditioned medium. ATX is known to contribute to cancer cell survival, growth, and invasion. Recentl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83a370c9afd3c9eaf9b8f04eea7dbf58
https://doi.org/10.1074/jbc.m512486200
https://doi.org/10.1074/jbc.m512486200
Autor:
Narie Sasaki, Mieko Satoh-Masuoka, Hiromu Murofushi, Yasutaka Kakiuchi, Kimiko Murakami-Murofushi
Publikováno v:
Biochemical and Biophysical Research Communications. 320:1351-1358
A new derivative of 1-phenyl-3-methyl-5-pyrazolone, 4,4-dichloro-1-(2,4-dichlorophenyl)-3-methyl-5-pyrazolone, named TELIN, was chemically synthesized and identified as a potent inhibitor of human telomerase in the cell-free telomeric repeat amplific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea8c2a0e1111e634cd0cc948c5a903b1
https://doi.org/10.1016/j.bbrc.2004.06.094
https://doi.org/10.1016/j.bbrc.2004.06.094
Autor:
Takatomi Yamada, Koji Okuhara, Hiromu Murofushi, Hidetaka Seo, Tetsu Akiyama, Hitoshi Kurumizaka, Takehiko Shibata, Kunihiro Ohta
Publikováno v:
Biochemical and Biophysical Research Communications. 303:8-13
DNA unwinding factor (DUF) was discovered as an essential DNA replication factor in Xenopus egg extracts. DUF consists of an HMG protein and a homolog of Cdc68p/Spt16p, and has the capability of unwinding dsDNA. Here we have examined the interaction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::413eba20190696c60ed6fd22fbe31e99
https://doi.org/10.1016/s0006-291x(03)00307-3
https://doi.org/10.1016/s0006-291x(03)00307-3
Autor:
Shohko Kunimoto, Isao Yamatsu, Wataru Murofushi, Tetsuyuki Kobayashi, Narie Sasaki, Yukie Hasegawa, Kimiko Murakami-Murofushi, Hiromu Murofushi, Susumu Kobayashi
Publikováno v:
Cell Structure and Function. 28:179-186
The cytoprotective effect of heat shock proteins (HSPs) promises new therapeutic modalities for medical treatment. We examined the anti-ulcer effect of cholesteryl glucoside (1-O-cholesteryl-beta-D-glucopyranoside, CG) on cold-restraint stress-induce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::560a3570d752fdc3170022c25c0b3f53
https://doi.org/10.1247/csf.28.179
https://doi.org/10.1247/csf.28.179