Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Hiromu Hattori"'
Publikováno v:
Organic Letters. 21:3456-3459
The unique 18-membered macrocyclic natural product mangrolide D was prepared in totally synthetic form. Key steps feature an Au-catalyzed glycosylation, aza-Michael addition, and LaLi3tris(binaphthoxide) catalyzed epoxidation. Detailed analysis of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91a21b44f4be0c5ee8a151afaae41d3c
https://doi.org/10.1021/acs.orglett.9b01256
https://doi.org/10.1021/acs.orglett.9b01256
Autor:
Joel Roesslein, Daniel Ritz, Katja Zerbe, Georg Rueedi, Karl Gademann, Patrick Caspers, Hideki Miyatake-Ondozabal, Hiromu Hattori
Publikováno v:
Angewandte Chemie. 130:11186-11190
The macrocyclic antibiotic mangrolide A has been described to exhibit potent activity against a number of clinically important Gram-negative pathogens. Reported is the first enantioselective total synthesis of mangrolide A and derivatives. Salient fe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a8339cd966e39835c2617fc19b0e364
https://doi.org/10.1002/ange.201805770
https://doi.org/10.1002/ange.201805770
Publikováno v:
The Journal of organic chemistry. 83(13)
The commercial macrolide antibiotic fidaxomicin was synthesized in a highly convergent manner. Salient features of this synthesis include a β-selective noviosylation, a β-selective rhamnosylation, a ring-closing metathesis, a Suzuki coupling, and a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d168690a43dda75c2fd130c524f1de19
https://pubmed.ncbi.nlm.nih.gov/29590752
https://pubmed.ncbi.nlm.nih.gov/29590752
Autor:
Hiromu Hattori
Publikováno v:
Journal of Synthetic Organic Chemistry, Japan. 76:1358-1359
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77bf775845935161d3cb18236835b7b1
https://doi.org/10.5059/yukigoseikyokaishi.76.1358
https://doi.org/10.5059/yukigoseikyokaishi.76.1358
Publikováno v:
Organic Letters
Org. Lett.
Org. Lett.
The first enantioselective total synthesis of fidaxomicin, also known as tiacumicin B or lipiarmycin A3, is reported. This novel glycosylated macrolide antibiotic is used in the clinic for the treatment of Clostridium difficile infections. Key featur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a1b1e438530285098748a476835fa02
http://pubs.acs.org/doi/abs/10.1021/acs.orglett.5b01602
http://pubs.acs.org/doi/abs/10.1021/acs.orglett.5b01602
Autor:
Hattori, Hiromu1, Roesslein, Joel1, Caspers, Patrick2, Zerbe, Katja1, Miyatake‐Ondozabal, Hideki1, Ritz, Daniel2, Rueedi, Georg2, Gademann, Karl1 karl.gademann@uzh.ch
Publikováno v:
Angewandte Chemie. 8/20/2018, Vol. 130 Issue 34, p11186-11190. 5p.