Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Hiromichi NAKAMUTA"'
Autor:
Ryo Fukuyama, Akio Shimokawa, Yasushi Kodama, Mitsugu Fujita, Yoshitaka Ohishi, Yuko Ando, Masao Koida, Hiromichi Nakamuta
Publikováno v:
Journal of Pharmacological Sciences, Vol 116, Iss 2, Pp 214-220 (2011)
Abstract.: The benzo[b]furan derivative MU314 inhibits in vitro bone resorption as potently as β-estradiol (E2). Here, we examined the point of action on the anti-osteoporotic effects of MU314. MU314 (10 nM) suppressed lacunae formation by osteoclas
Externí odkaz:
https://doaj.org/article/9a65eb77bf734b59b6c8d17972d2ac6d
Publikováno v:
In Japanese Journal of Pharmacology 1999 79(3):379-386
Autor:
Masao Koida, Ikuo Kawasaki, Yuko Ando, Takahiro Ohishi, Hidemi Kanemura, Yoshitaka Ohishi, Ryo Fukuyama, Hiromichi Nakamuta, Kiyoharu Nishide, Yukako Tabuchi, Shunsaku Ohta
Publikováno v:
Bioorganic & Medicinal Chemistry
Graphical abstract Preparation of novel (Z)-4-ylidenebenzo[b]furo[3,2-d][1,3]oxazines and their biological activities such as anti-osteoclastic bone resorption activity, antagonistic activity of the cysLT1 receptor and growth inhibitory activity for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12436d2a413dc1f597617e01798187ff
https://doi.org/10.1016/j.bmc.2009.04.017
https://doi.org/10.1016/j.bmc.2009.04.017
Autor:
Hiromichi Nakamuta, David M. Hougaard, Masashi Shin, Kunio Fujiwara, Lars-Inge Larsson, Koji Ohara
Publikováno v:
Histochemistry and Cell Biology. 128:285-290
The cancer drug daunomycin is used in treatment of leukemia but possesses severe side effects that involve the gastrointestinal tract. We therefore used a newly developed immunocytochemical procedure to determine the distribution of DM in the gastroi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d1871eb88d89d4ee1714fdb0e6acbc2
https://doi.org/10.1007/s00418-007-0314-6
https://doi.org/10.1007/s00418-007-0314-6
Autor:
Kumiko Ando, Shunsaku Ohta, Masao Koida, Yoshitaka Ohishi, Jun-ichi Kunitomo, Mami Yamaguchi, Masayuki Yamashita, Yuko Ando, Hiromichi Nakamuta, Ryo Fukuyama
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 16:5849-5854
A novel oxazine ring formation method was established using the reaction of 2-acetyl-( E )-3-styrylcarbonylaminobenzo[ b ]furans ( 4 ) with Vilsmeier–Haack–Arnold reagent to afford ( E and Z )-(( E )-2-styrylbenzo[ b ]furo[3,2- d ][1,3]oxazin-4-y
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45e667e0fde4757130b8ff27cc050cdd
https://doi.org/10.1016/j.bmcl.2006.08.064
https://doi.org/10.1016/j.bmcl.2006.08.064
Autor:
Giuseppina Andreotti, Andrea Motta, Pietro Amodeo, Blanca López Méndez, Maria Antonietta Castiglione Morelli, Hiromichi Nakamuta
Publikováno v:
Journal of Biological Chemistry. 281:24193-24203
Salmon calcitonin (sCT) forms an amphipathic helix in the region 9–19, with the C-terminal decapeptide interacting with the helix (Amodeo, P., Motta, A., Strazzullo, G., Castiglione Morelli, M. A. (1999) J. Biomol. NMR 13, 161–174). To uncover th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::437e8705fdd40e557dfba7f7347d6ba6
https://doi.org/10.1074/jbc.m603528200
https://doi.org/10.1074/jbc.m603528200
Autor:
Masao Koida, Ryo Fukuyama, Hiromichi Nakamuta, Ippei Tanaka, Nobuo Izumo, Satoshi Shimegi, Atsushi Kiuchi
Publikováno v:
International Journal of Sport and Health Science. 4:10-18
The purpose of this study was to investigate the effects of different intensities of resistance exercise training on established bone loss in ovariectomized (ovx-ed) rats by densitometry and histomorphometry. Thirty Female Wistar rats were ovx-ed or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::365b453230a416c5a725f89262c6c9d9
https://doi.org/10.5432/ijshs.4.10
https://doi.org/10.5432/ijshs.4.10
Autor:
Toshihisa Komori, Takashi Fujita, Masao Koida, Hiromichi Nakamuta, Yasu-Taka Azuma, Akihiko Hirano, Ryo Fukuyama
Publikováno v:
Biochemical and Biophysical Research Communications. 315:636-642
Cell migration is a key event in repair and remodeling of skeletal tissues, but the mechanism of osteoblast migration has not been resolved. Statins, which are inhibitors of 3-hydroxy-3-methylglutaryl CoA reductase, increase bone. However, the effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce01029e3b283938445964674bf2547b
https://doi.org/10.1016/j.bbrc.2004.01.104
https://doi.org/10.1016/j.bbrc.2004.01.104
Publikováno v:
Journal of Biological Chemistry. 277:22191-22200
cAMP signaling, activated by extracellular stimuli such as parathyroid hormone, has cell type-specific effects important for cellular proliferation and differentiation in bone cells. Recent evidence of a second enzyme target for cAMP suggests diverge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dad2bd9ae511debc7dc06a892873e9dd
https://doi.org/10.1074/jbc.m110364200
https://doi.org/10.1074/jbc.m110364200
Autor:
Takeyuki Kohno, Takashi Fujita, Masao Koida, Tohru Meguro, Hiromichi Nakamuta, Ryo Fukuyama, Nobuo Izumo
Publikováno v:
Biochemical and Biophysical Research Communications. 280:348-352
Inorganic phosphate (Pi) supplement is generally used to accelerate mineralization of cultured bone cells but the mechanism of action is totally unknown. How the action is related with the transactivation of Runx2/Cbfa1,a master gene product of bone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3a72fce9b08b9105bb7ae4e23a6d515
https://doi.org/10.1006/bbrc.2000.4108
https://doi.org/10.1006/bbrc.2000.4108