Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Hiromichi, Nakabayashi"'
Autor:
Keiji Shimizu, Ayano Kumazawa, Hiromichi Nakabayashi, Takanori Masahira, Toshio Yawata, Eiichi Nakai, Takao Kaji, Shinichi Toyonaga, Kae Chang Park, Takahiro Chihara
Publikováno v:
Molecular Carcinogenesis. 49:532-544
Cancer stem cells are an important target for effective therapy, since they show tumorigenicity, chemoresistance, and radioresistance. We isolated cancer stem cells from glioma cell lines and tissues and examined the expression of cancer testis antig
Autor:
Hiroshi Maruyama, Toshihiro Takao, Yasumasa Iwasaki, Koichi Asaba, Keiji Shimizu, Hiromichi Nakabayashi, Kozo Hashimoto, Naoko Ogami, Makoto Tsugita
Publikováno v:
Endocrine Journal. 55:425-428
An 81-year-old man was admitted to our hospital because of general fatigue. Hormonal examination showed that he had panhypopituitarism and central diabetes insipidus. MRI imaging revealed the presence of large cystic mass with suprasellar extension i
Autor:
Teruaki Nakagomi, Shoko M. Yamada, Kae Chang Park, Keiji Shimizu, Shinichi Toyonaga, Hiromichi Nakabayashi, Nobufumi Yasuda, Eiji Tsubosaki, Matsuyoshi Nakasato
Publikováno v:
Neurology : official journal of the American Academy of Neurology. 69(10):974-978
Objective: To investigate the relationship between leukoaraiosis (LA), which has been considered as an intermediate substitute of ischemic brain damages, and metabolic syndrome (MetS), which attracts attention as a risk factor for cerebrovascular dis
Autor:
Shoko M. Yamada, Keiji Shimizu, Shinichi Toyonaga, Hiromichi Nakabayashi, Mitsuhiro Hara, Manabu Nakashima, Kae Chang Park
Publikováno v:
Cancer Letters. 246:182-189
RCAS1, one of the tumor cell surface antigens, is strongly expressed in aggressive tumors. RCAS1 suppresses the in vitro growth of immune effector cells. We investigated the expression of RCAS1 in 57 gliomas using immunohistochemistry. Furthermore, w
Publikováno v:
Journal of Clinical Pathology. 59:725-728
Background: CDC25B is a cell-cycle regulatory protein, which is considered to be related to tumorigenesis and progression of tumours. Aims: To elucidate the role of CDC25B in glioma, the expression of CDC25B and the association of the CDC25B expressi
Autor:
Kae Chang Park, Shoko M. Yamada, Hiromichi Nakabayashi, Shinichi Toyonaga, Keiji Shimizu, Eiichi Nakai
Publikováno v:
Journal of Nippon Medical School. 72:308-311
Nocardial brain abscesses are uncommon and are not preceded by clear infectious symptoms in most cases. Delayed identification of the bacteria is responsible for a high mortality rate. A 58-year-old afebrile woman was admitted to our hospital because
Autor:
Keiji Shimizu, Hiromichi Nakabayashi
Publikováno v:
BMC Cancer
BMC Cancer, Vol 12, Iss 1, p 453 (2012)
BMC Cancer, Vol 12, Iss 1, p 453 (2012)
Background Glioblastoma is the most common and most aggressive form of malignant glioma and is very difficult to treat. Controlling tumour cell invasion and angiogenesis is essential to improve the prognosis of glioblastoma patients. Since constituti
Autor:
Hiromichi Nakabayashi, Keiji Shimizu
Publikováno v:
Cancer science. 102(2)
Malignant gliomas are characterized by high invasive potential and strong angiogenic ability. Constitutive activation of Rho and its downstream target Rho-kinase are crucial for tumor progression. We investigated the effect of the Rho-kinase inhibito
Autor:
Toshio, Yawata, Eiichi, Nakai, Kae Chang, Park, Takahiro, Chihara, Ayano, Kumazawa, Shinichi, Toyonaga, Takanori, Masahira, Hiromichi, Nakabayashi, Takao, Kaji, Keiji, Shimizu
Publikováno v:
Molecular carcinogenesis. 49(6)
Cancer stem cells are an important target for effective therapy, since they show tumorigenicity, chemoresistance, and radioresistance. We isolated cancer stem cells from glioma cell lines and tissues and examined the expression of cancer testis antig
Autor:
Toshio Yawata, Kae Chang Park, Eiichi Nakai, Ayano Kumazawa, Keiji Shimizu, Takahiro Chihara, Hiromichi Nakabayashi
Publikováno v:
Cancer investigation. 27(9)
We established a cancer stem (CS) cell line, U87CS, by means of spheroid culture of U87MG cells derived from glioblastoma (GBM) in neuronal stem cell medium. U87CS cells presented positive immunohistochemical staining for multidrug resistance (MDR)1