Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Hiromi SHIMOJO"'
Autor:
Yao Zhang, Ines Lahmann, Katharina Baum, Hiromi Shimojo, Philippos Mourikis, Jana Wolf, Ryoichiro Kageyama, Carmen Birchmeier
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
The cell source and dynamics of Notch ligands during the regulation of muscle stem cells is unclear. Here, the authors show that the Notch ligand Dll1 has to oscillate in order to control the balance between self-renewal and differentiation of muscle
Externí odkaz:
https://doaj.org/article/afeed375ae874570b42ac52637193643
Autor:
Yao Zhang, Ines Lahmann, Katharina Baum, Hiromi Shimojo, Philippos Mourikis, Jana Wolf, Ryoichiro Kageyama, Carmen Birchmeier
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-1 (2021)
A Correction to this paper has been published: https://doi.org/10.1038/s41467-021-22144-w
Externí odkaz:
https://doaj.org/article/310a63efc61b41569b34ddea83c0a8da
Publikováno v:
Physiology (Bethesda, Md.). 38(2)
The significance of the coupling delay, which is the time required for interactions between coupled oscillators, in various oscillatory dynamics has been investigated mathematically for more than three decades, but its biological significance has bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c329fb5f593b9099d1057efb13aff137
https://pubmed.ncbi.nlm.nih.gov/36256636
https://pubmed.ncbi.nlm.nih.gov/36256636
Publikováno v:
Proceedings of the Japan Academy. Series B, Physical and Biological Sciences
Neural stem cells (NSCs) actively proliferate and generate neurons and glial cells (active state) in the embryonic brain, whereas they are mostly dormant (quiescent state) in the adult brain. The expression dynamics of Hes1 are different between acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a89026fce96233c0bf491710217fbd64
https://doi.org/10.2183/pjab.96.026
https://doi.org/10.2183/pjab.96.026
Autor:
Jana Wolf, Hiromi Shimojo, Ines Lahmann, Yao Zhang, Ryoichiro Kageyama, Carmen Birchmeier, Katharina Baum, Philippos Mourikis
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-1 (2021)
Nature Communications
Nature Communications
Cell-cell interactions mediated by Notch are critical for the maintenance of skeletal muscle stem cells. However, dynamics, cellular source and identity of functional Notch ligands during expansion of the stem cell pool in muscle growth and regenerat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7592497814c568f00f971ac948ff7d55
https://doi.org/10.1038/s41467-021-22144-w
https://doi.org/10.1038/s41467-021-22144-w
Autor:
Deidiane Elisa Ribeiro, Juliana Corrêa-Velloso, Patrícia Pereira Lopes Martins, Talita Glaser, Ryoichiro Kageyama, Hiromi Shimojo, Vanessa Fernandes Arnaud Sampaio, Renata Beco, Henning Ulrich, Claudiana Lameu, Ana Paula Santos, Yang D. Teng, Ágatha Oliveira-Giacomelli, Hellio Danny Nóbrega de Souza, Michal Kosinski
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Calcium, the most versatile second messenger, regulates essential biology including crucial cellular events in embryogenesis. We investigated impacts of calcium channels and purinoceptors on neuronal differentiation of normal mouse embryonic stem cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eee8029b77d6e723282e5369b8c1482a
Autor:
Junichiro Takaya, Itaru Imayoshi, Hiromi Shimojo, Ryoichiro Kageyama, Mihoko Takenoya, Naasson Mbambi Mbenza, Yuzo Kodama, Jun Iwata, Kumiko Kobayashi, Motonari Uesugi, Amélie Perron, Yoshihiro Nishikawa
Publikováno v:
Journal of Biological Chemistry. 293:8285-8294
The transcription factor Hes family basic helix-loop-helix transcription factor 1 (Hes1) is a downstream effector of Notch signaling and plays a crucial role in orchestrating developmental processes during the embryonic stage. However, its aberrant s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5140294e61823dc0b0daa1ac717a42e
https://doi.org/10.1074/jbc.ra118.002316
https://doi.org/10.1074/jbc.ra118.002316
Autor:
Ryoichiro Kageyama, Hiromi Shimojo
Publikováno v:
Journal of visualized experiments : JoVE. (154)
Notch signaling regulates the maintenance of neural stem/progenitor cells by cell-cell interactions. The components of Notch signaling exhibit dynamic expression. Notch signaling effector Hes1 and the Notch ligand Delta-like1 (Dll1) are expressed in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::900dd619b22c613701a4a67e7e38475a
https://pubmed.ncbi.nlm.nih.gov/31885384
https://pubmed.ncbi.nlm.nih.gov/31885384
Autor:
Talita, Glaser, Hiromi, Shimojo, Deidiane Elisa, Ribeiro, Patrícia Pereira Lopes, Martins, Renata Pereira, Beco, Michal, Kosinski, Vanessa Fernandes Arnaud, Sampaio, Juliana, Corrêa-Velloso, Ágatha, Oliveira-Giacomelli, Claudiana, Lameu, Ana Paula, de Jesus Santos, Héllio Danny Nóbrega, de Souza, Yang D, Teng, Ryoichiro, Kageyama, Henning, Ulrich
Publikováno v:
Molecular psychiatry. 26(6)
Calcium, the most versatile second messenger, regulates essential biology including crucial cellular events in embryogenesis. We investigated impacts of calcium channels and purinoceptors on neuronal differentiation of normal mouse embryonic stem cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2c355fbe124598e237c0cbdad353f90f
https://pubmed.ncbi.nlm.nih.gov/32350390
https://pubmed.ncbi.nlm.nih.gov/32350390
Publikováno v:
Development (Cambridge, England). 147(4)
The expression of the transcriptional repressor Hes1 oscillates in many cell types, including neural progenitor cells (NPCs), but the significance of Hes1 oscillations in development is not fully understood. To examine the effect of altered oscillato
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed431181d3532792dcef221f5b94d301
https://pubmed.ncbi.nlm.nih.gov/32094111
https://pubmed.ncbi.nlm.nih.gov/32094111