Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Hiromi Ogata"'
Autor:
Nobuyo Higashi-Kuwata, Kohei Tsuji, Hironori Hayashi, Haydar Bulut, Maki Kiso, Masaki Imai, Hiromi Ogata-Aoki, Takahiro Ishii, Takuya Kobayakawa, Kenta Nakano, Nobutoki Takamune, Naoki Kishimoto, Shin-ichiro Hattori, Debananda Das, Yukari Uemura, Yosuke Shimizu, Manabu Aoki, Kazuya Hasegawa, Satoshi Suzuki, Akie Nishiyama, Junji Saruwatari, Yukiko Shimizu, Yoshikazu Sukenaga, Yuki Takamatsu, Kiyoto Tsuchiya, Kenji Maeda, Kazuhisa Yoshimura, Shun Iida, Seiya Ozono, Tadaki Suzuki, Tadashi Okamura, Shogo Misumi, Yoshihiro Kawaoka, Hirokazu Tamamura, Hiroaki Mitsuya
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Effective antivirals are critical for combatting SARS-CoV-2 infections. Here, the authors develop two orally available small molecules, which specifically inhibit the activity of the SARS-CoV-2 main protease and potently block the infectivity and rep
Externí odkaz:
https://doaj.org/article/0a9319e808d143a0af10cb89193b1a4f
Autor:
Kanako Kishi, Hiromi Ogata, Seiji Ogata, Yuri Mizusawa, Eri Okamoto, Yukiko Matsumoto, Shoji Kokeguchi, Masahide Shiotani
Publikováno v:
Journal of Clinical and Diagnostic Research, Vol 9, Iss 11, Pp QC14-QC16 (2015)
Introduction: Multiple rounds of centrifugation or washing spermatozoa can cause sperm DNA fragmentation (SDF); however, a microfluidic approach to select spermatozoa does not require centrifugation. Reports have suggested that sperm sorting using
Externí odkaz:
https://doaj.org/article/1708bd9ccb494ecc9ef028ff7fa74ca6
Autor:
Hiromi Ogata
Publikováno v:
The Journal of Island Studies. 23:139-153
Autor:
Masakazu Kakuni, Naoki Kishimoto, Hiroki Kumamoto, Yasuhito Tanaka, Debananda Das, Nobutoki Takamune, Shogo Misumi, David Venzon, Hiromi Ogata-Aoki, Haydar Bulut, David A. Davis, Nobuyo Higashi-Kuwata, Hiroaki Mitsuya, Sanae Hayashi, Masaki Otagiri, Mai Hashimoto, Shin-ichiro Hattori
Publikováno v:
J Hepatol
Background & Aims While certain nucleos(t)ide reverse transcriptase inhibitors (NRTIs) are efficacious in treating HBV infection, their effects are yet to be optimized and the emergence of NRTI-resistant HBV variants is an issue because of the requir
Autor:
Hiromi Ogata
Publikováno v:
The Journal of Island Studies. 22:93-108
Autor:
Masayoshi Onitsuka, Mitsuo Umetsu, Takeshi Omasa, Izumi Kumagai, Shota Konno, Takeshi Nakanishi, Ryutaro Asano, Mai Okada, Katsuhiro Hosokawa, Ippei Shimomura, Hiromi Ogata, Shintaro Taki, Kyoko Arai
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-8 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-8 (2020)
Designing non-natural antibody formats is a practical method for developing highly functional next-generation antibody drugs, particularly for improving the therapeutic efficacy of cancer treatments. One approach is constructing bispecific antibodies
Autor:
Shin ichiro Hattori, Nobuyo Higashi-Kuwata, Seiji Okada, Manabu Aoki, Akinobu Hamada, Yumi Hashiguchi, Hiromi Ogata-Aoki, Matthew Danish, Hiroaki Mitsuya, Chiemi Shiotsu, Hisataka Kobayashi, Hironori Hayashi, Hironobu Ihn
Publikováno v:
Antiviral Research. 149:78-88
Employing NOD/SCID/Jak3-/- mice transplanted with human PBMCs (hNOJ mice) and replication-competent, red-fluorescent-protein (mCherry; mC)-labeled HIV-1JR-FL (HIVmC), we examined whether early antiretroviral treatment blocked the establishment of HIV
Autor:
Yukiko Matsumoto, Yuri Mizusawa, Shoji Kokeguchi, Hiromi Ogata, Eri Okamoto, Masahide Shiotani, Kohyu Furuhashi, Satoshi Yamada, Seiji Ogata
Publikováno v:
Reproductive Medicine and Biology
Aim Human chorionic gonadotropin (hCG) is used frequently for luteal support in fresh in vitro fertilization cycles as it induces progesterone secretion from the ovaries after oocyte retrieval and modulates the endometrium for implantation in fresh c
Autor:
Masao Yasufuku, Kazuya Ise, Hiroaki Masuyama, Keiichi Uchida, Miyuki Kohno, Motoshi Wada, Masahito Sato, Hiromi Ogata, Yoshiki Morotomi, Yoshinori Hamada
Publikováno v:
Pediatric Surgery International. 33:33-41
The purpose of this study is to identify the current clinical features of neonatal gastrointestinal perforation in Japan. A questionnaire about cases of neonatal gastrointestinal perforation treated in recent 5 years was sent to participating institu
Autor:
Izumi Kumagai, Ryutaro Asano, Ryota Orimo, Shozo Furumoto, Mitsuo Umetsu, Noriaki Koyama, Yasuyo Hagiwara, Kyoko Arai, Yosuke Masakari, Hiromi Ogata
Publikováno v:
FEBS Open Bio
The development of single‐chain variable fragments (scFvs) as therapeutic agents has the potential to reduce the high cost of antibody production, but the development process often impairs scFv functions such as binding affinity and pharmacokinetic