Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Hiromi Koma"'
Publikováno v:
Brain and Behavior, Vol 10, Iss 12, Pp n/a-n/a (2020)
Abstract Introduction 15‐deoxy‐Δ12,14‐prostaglandin J2 (15d‐PGJ2) causes neuronal apoptosis independently of its nuclear receptor, peroxysome‐proliferator activated receptor γ. Its membrane receptor, chemoattractant receptor‐homologous
Externí odkaz:
https://doaj.org/article/96ddf63fc2fb41e4a42d5952dd3ef49a
Publikováno v:
Biochemistry and Biophysics Reports, Vol 9, Iss C, Pp 61-66 (2017)
An endogenous anticancer agent, 15-deoxy -Δ12,14-prostaglandin J2 (15d-PGJ2) induces apoptosis in the chemoresistant renal cell carcinoma (RCC). Peroxisome proliferator-activated receptor-γ (PPARγ) is a nuclear receptor for 15d-PGJ2, and mediates
Externí odkaz:
https://doaj.org/article/6b1541e1346b4ef9ae1aee375092f95e
Publikováno v:
Biochemistry and Biophysics Reports, Vol 18, Iss , Pp - (2019)
Renal cell carcinoma (RCC) is relatively resistant to chemotherapy and radiotherapy. Clear cell RCC (ccRCC) accounts for the majority of RCC, which have mutations or epigenetic silencing of the von Hippel–Lindau (VHL) gene. VHL-positive Caki-2 cell
Externí odkaz:
https://doaj.org/article/556357dfbb21411f881967bec183d518
Publikováno v:
Biological and Pharmaceutical Bulletin. 43:153-157
Renal cell carcinoma (RCC) is one of the chemoresistant cancers. There is a pressing need to establish therapeutic approaches to prevent RCC proliferation and metastasis. The electrophilic 15-deoxy-Δ12,14-prostaglandin J2 (15d-PGJ2) is an endogenous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df514067fbad28d98960071e56e18ebb
https://doi.org/10.1248/bpb.b19-00748
https://doi.org/10.1248/bpb.b19-00748
Publikováno v:
Biological and Pharmaceutical Bulletin. 42:1913-1920
4,4-Diisothiocyanatostilbene disulfonic acid (DIDS), an antagonist of anion channel including voltage-dependent anion channel (VDAC), acts as both neurotoxicant and neuroprotectant, resulting in the controversy. VDAC contributes to neuronal apoptosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e68ba8a50e49fc02c311d35405ff6aaa
https://doi.org/10.1248/bpb.b19-00536
https://doi.org/10.1248/bpb.b19-00536
Publikováno v:
Brain and Behavior, Vol 10, Iss 12, Pp n/a-n/a (2020)
Introduction 15-deoxy-Δ12,14 -prostaglandin J2 (15d-PGJ2 ) causes neuronal apoptosis independently of its nuclear receptor, peroxysome-proliferator activated receptor γ. Its membrane receptor, chemoattractant receptor-homologous molecule expressed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d60832e91768dfdb4e2ed534a6f716ec
https://doi.org/10.1002/brb3.1866
https://doi.org/10.1002/brb3.1866
Publikováno v:
Biologicalpharmaceutical bulletin. 43(1)
Renal cell carcinoma (RCC) is one of the chemoresistant cancers. There is a pressing need to establish therapeutic approaches to prevent RCC proliferation and metastasis. The electrophilic 15-deoxy-Δ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5f8db1f0ecdd1032fdf83ca7c4a313bb
https://pubmed.ncbi.nlm.nih.gov/31902920
https://pubmed.ncbi.nlm.nih.gov/31902920
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. 96:3-B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc5a4c61455e9071ae3f7c1deb0da014
https://doi.org/10.1254/jpssuppl.96.0_3-b-p-233
https://doi.org/10.1254/jpssuppl.96.0_3-b-p-233
Publikováno v:
Molecular Neurobiology. 55:2227-2248
Prostaglandins (PGs) are divided into conventional PGs, e.g., PGD2, and cyclopentenone-type PGs, e.g., 15-deoxy-Δ12,14 prostaglandin J2 (15d-PGJ2). PGD2 is non-enzymatically metabolized to PGJ2, Δ12-PGJ2, and 15d-PGJ2. In the central nervous system
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b7f4490ef83376fe9f122fba1020fe4
https://doi.org/10.1007/s12035-017-0435-4
https://doi.org/10.1007/s12035-017-0435-4