Identification of novel low-dose bisphenol a targets in human foreskin fibroblast cells derived from hypospadias patients.

Autor: Xian-Yang Qin, Yoshiyuki Kojima, Kentaro Mizuno, Katsuhiko Ueoka, Koji Muroya, Mami Miyado, Hiroko Zaha, Hiromi Akanuma, Qin Zeng, Tomokazu Fukuda, Jun Yoshinaga, Junzo Yonemoto, Kenjiro Kohri, Yutaro Hayashi, Maki Fukami, Tsutomu Ogata, Hideko Sone

Publikováno v: PLoS ONE, Vol 7, Iss 5, p e36711 (2012)

The effect of low-dose bisphenol A (BPA) exposure on human reproductive health is still controversial. To better understand the molecular basis of the effect of BPA on human reproductive health, a genome-wide screen was performed using human foreskin

Externí odkaz: https://doaj.org/article/07c19c20bf324e9181240ac97ee3a05d

Phylogeographic insights into the invasion history and secondary spread of the signal crayfish in Japan

Autor: Nisikawa Usio, Julian D. Olden, Noriko Azuma, Eric Larson, Kenzi Takamura, Cathryn L. Abbott, Hiromi Akanuma, Noriko Takamura

Publikováno v: Ecology and Evolution

Successful invasion by nonindigenous species is often attributed to high propagule pressure, yet some foreign species become widespread despite showing reduced genetic variation due to founder effects. The signal crayfish (Pacifastacus leniusculus) i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e99be95cc72d165a9e6431318c3946ce
http://hdl.handle.net/2297/46188

Multi-Parametric Profiling Network Based on Gene Expression and Phenotype Data: A Novel Approach to Developmental Neurotoxicity Testing

Autor: Xian-Yang Qin, Jun Yoshinaga, Hiroyoshi Toyoshiba, Hiromi Akanuma, Satoshi Imanishi, Hideko Sone, Reiko Nagano, Seiichiroh Ohsako

Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 13, Iss 1, Pp 187-207 (2011)
Volume 13
Issue 1
Pages 187-207

The establishment of more efficient approaches for developmental neurotoxicity testing (DNT) has been an emerging issue for children’s environmental health. Here we describe a systematic approach for DNT using the neuronal differentiation of mouse

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cbd98efa38dc03aef988705aca42999
https://doi.org/10.3390/ijms13010187

Prediction of developmental chemical toxicity based on gene networks of human embryonic stem cells

Autor: Hideko Sone, Sachiyo Aburatani, Hiromi Akanuma, Junko Yamane, Reiko Nagano, Satoshi Imanishi, Seiichiroh Ohsako, Wataru Fujibuchi, Tsuyoshi Kato

Publikováno v: Nucleic Acids Research

Predictive toxicology using stem cells or their derived tissues has gained increasing importance in biomedical and pharmaceutical research. Here, we show that toxicity category prediction by support vector machines (SVMs), which uses qRT-PCR data fro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17cb313a0c1246272e6aa77010389224
http://europepmc.org/articles/PMC6379709

Effectiveness of Wildlife-Friendly Farming on Aquatic Macroinvertebrate Diversity on Sado Island in Japan

Autor: Nisikawa Usio, Hiromi Akanuma, Ryugo Watanabe, Ryoji Saito

Publikováno v: Ecological Research Monographs ISBN: 9784431553298

Paddy fields are important as alternative wetland habitats for a range of aquatic and semi-aquatic wildlife that once inhabited floodplain habitats. However, depopulation and aging in rural communities have led to the loss of biodiversity across rura

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b16454eb4688afd9fc1a34546e3e0016
https://doi.org/10.1007/978-4-431-55330-4_7