Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Hiromi, Shimazaki"'
Autor:
HIROMI SHIMAZAKI, ITARU UTAGAWA, CHIEMI SANO, SHINOBU SAKURADA, KYOUHEI YAMASHITA, NOBUTO SHIBATA, TUNEYOSHI OTA, TADASHI FUKUSHIMA
Publikováno v:
Juntendo Medical Journal. 68:261-270
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8926b4dc0d5687e538d0349ba695cc2
https://doi.org/10.14789/jmj.jmj22-0002-oa
https://doi.org/10.14789/jmj.jmj22-0002-oa
Autor:
Nobuto Shibata, Yumiko Motoi, Hiroyuki Tomiyama, Tohru Ohnuma, Bolati Kuerban, Katrin Tomson, Miwa Komatsu, Hiromi Shimazaki, Nobutaka Hattori, Heii Arai
Publikováno v:
Dementia and Geriatric Cognitive Disorders Extra, Vol 3, Iss 1, Pp 161-167 (2013)
Background and Aims: Similar clinical and pathological features have been observed in Alzheimer's disease (AD) and Parkinson's disease with dementia (PDD). Both the peroxisome proliferator-activated receptor-γ (PPAR-γ) gene and the peroxisome proli
Externí odkaz:
https://doaj.org/article/86ac6a0fd3ca4cfc8e44828b19a1d94d
Autor:
Tohru Ohnuma, Tohru Nakamura, Yuto Takebayashi, Ryo Hanzawa, Maiko Kitazawa, Ryoko Higashiyama, Mayu Takeda, Katrin Thompson, Miwa Komatsu, Hiromi Shimazaki, Nobuto Shibata, Heii Arai
Publikováno v:
Dementia and Geriatric Cognitive Disorders Extra, Vol 2, Iss 1, Pp 496-502 (2012)
Background/Aims: PiggyBac transposable element derived 1 (PGBD1) encodes a molecule involved in epigenetic mechanisms that have been implicated in Alzheimer’s disease (AD), and recent genome-wide association studies and meta-analyses have indicated
Externí odkaz:
https://doaj.org/article/8703d06e5ac0484191a653f5cbd09579
Autor:
Tomoyuki Nagata, Kazuhiko Nakayama, Nobuto Shibata, Yuko Tagata, Hiromi Shimazaki, Hisashi Yamada, Tomoko Nakada, Koji Kasanuki, Aiko Toda, Tohru Ohnuma, Heii Arai, Kenji Tagai, Eri Kawai, Shunichiro Shinagawa
Publikováno v:
International Journal of Geriatric Psychiatry. 30:927-933
Objective Catechol-O-methyltransferase (COMT) plays an important role in dopamine degradation, which is associated with the pathophysiology of Alzheimer's disease (AD) and alcoholism. A functional COMT polymorphism, Val158Met (rs4680 G > A), affects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a20e3d7d4ad377f522b87721e100285
https://doi.org/10.1002/gps.4237
https://doi.org/10.1002/gps.4237
Publikováno v:
Juntendo Medical Journal. 60:337-344
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1286a3e2ffc70449142a5b11aeb00d66
https://doi.org/10.14789/jmj.60.337
https://doi.org/10.14789/jmj.60.337
Autor:
Heii Arai, Miwa Komatsu, Yuko Tagata, Bolati Kuerban, Nobuto Shibata, Hiromi Shimazaki, Aiko Toda, Tohru Ohnuma, Katrin Tomson, Tomoko Nakada
Publikováno v:
Journal of Neural Transmission. 121:427-432
Since ethanol and its metabolite, acetaldehyde, are directly neurotoxic, alcohol intake could affect the development of Alzheimer's disease (AD). Mitochondrial aldehyde dehydrogenase 2 (ALDH2) metabolizes acetaldehyde into acetate and also protects a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f211c58f66983c027ce9606fe57699a
https://doi.org/10.1007/s00702-013-1112-z
https://doi.org/10.1007/s00702-013-1112-z
Autor:
Hiromi Shimazaki, Katrin Tomson, Bolati Kuerban, Nobuto Shibata, Nobutaka Hattori, Yumiko Motoi, Tohru Ohnuma, Hiroyuki Tomiyama, Heii Arai, Miwa Komatsu
Publikováno v:
Dementia and Geriatric Cognitive Disorders Extra, Vol 3, Iss 1, Pp 161-167 (2013)
Background and Aims: Similar clinical and pathological features have been observed in Alzheimer's disease (AD) and Parkinson's disease with dementia (PDD). Both the peroxisome proliferator-activated receptor-γ (PPAR-γ) gene and the peroxisome proli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::431b5d4805e73265fefada516bccf002
http://www.karger.com/Article/FullText/351419
http://www.karger.com/Article/FullText/351419
Autor:
Miwa Komatsu, Tohru Nakamura, Nobuto Shibata, Ryo Hanzawa, Heii Arai, Katrin Thompson, Maiko Kitazawa, Mayu Takeda, Tohru Ohnuma, Hiromi Shimazaki, Yuto Takebayashi, Ryoko Higashiyama
Publikováno v:
Dementia and Geriatric Cognitive Disorders Extra, Vol 2, Iss 1, Pp 496-502 (2012)
Dementia and Geriatric Cognitive Disorders EXTRA
Dementia and Geriatric Cognitive Disorders EXTRA
Background/Aims: PiggyBac transposable element derived 1 (PGBD1) encodes a molecule involved in epigenetic mechanisms that have been implicated in Alzheimer’s disease (AD), and recent genome-wide association studies and meta-analyses have indicated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c00fa7d7dc2333b6ecc2c313de2c7e05
https://doi.org/10.1159/000345085
https://doi.org/10.1159/000345085
Publikováno v:
Journal of the Japan Institute of Metals. 71:336-341
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d86f197c144303568b295623a25fdd41
https://doi.org/10.2320/jinstmet.71.336
https://doi.org/10.2320/jinstmet.71.336
Genetic Association Between KIBRA Polymorphism and Alzheimer's Disease with in a Japanese Population
Autor:
Eri, Kawai, Nobuto, Shibata, Tomoyuki, Nagata, Shunichiro, Shinagawa, Kenji, Tagai, Kenji, Tgai, Tohru, Ohnuma, Hiromi, Shimazaki, Aiko, Toda, Koji, Kasanuki, Toshiki, Takayama, Ayako, Suzuki, Kazuhiko, Nakayama, Hisashi, Yamada, Heii, Arai
Publikováno v:
Neuromolecular medicine. 17(2)
KIBRA plays an important role in synaptic plasticity in human hippocampus related to cognitive function. Functional studies suggest that KIBRA is a potential candidate gene for memory and Alzheimer's disease (AD) risk. A single nucleotide polymorphis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bae0f0b6cbdffe0a5a5d3df2ffcd019f
https://pubmed.ncbi.nlm.nih.gov/25896477
https://pubmed.ncbi.nlm.nih.gov/25896477