Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Hiromi, Sakawaki"'
Autor:
Hiroshi Ishii, Kazutaka Terahara, Takushi Nomura, Midori Okazaki, Hiroyuki Yamamoto, Tsugumine Shu, Hiromi Sakawaki, Tomoyuki Miura, David I. Watkins, Tetsuro Matano
Publikováno v:
Molecular Therapy. 30:2048-2057
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bba24636a945f10d75d55a61eee45fba
https://doi.org/10.1016/j.ymthe.2022.02.023
https://doi.org/10.1016/j.ymthe.2022.02.023
Autor:
Naoya Doi, Tomoyuki Miura, Hiromi Mori, Hiromi Sakawaki, Takaaki Koma, Akio Adachi, Masako Nomaguchi
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
A major issue for present HIV-1 research is to establish model systems that reflect or mimic viral replication and pathogenesis actually observed in infected humans. To this end, various strategies using macaques as infection targets have long been p
Externí odkaz:
https://doaj.org/article/b59a86f01ef04635900cc2fa66eba651
Autor:
Sayuri Seki, Takushi Nomura, Masako Nishizawa, Hiroyuki Yamamoto, Hiroshi Ishii, Saori Matsuoka, Teiichiro Shiino, Hironori Sato, Kazuta Mizuta, Hiromi Sakawaki, Tomoyuki Miura, Taeko K Naruse, Akinori Kimura, Tetsuro Matano
Publikováno v:
PLoS Pathogens, Vol 13, Iss 9, p e1006638 (2017)
CD8+ T-cell responses exert strong suppressive pressure on HIV replication and select for viral escape mutations. Some of these major histocompatibility complex class I (MHC-I)-associated mutations result in reduction of in vitro viral replicative ca
Externí odkaz:
https://doaj.org/article/8120dd362c2d4c40ba1d3654c5bed8dc
Env-independent protection of intrarectal SIV challenge by vaccine induction of Gag/Vif-specific CD8
Autor:
Hiroshi, Ishii, Kazutaka, Terahara, Takushi, Nomura, Midori, Okazaki, Hiroyuki, Yamamoto, Tsugumine, Shu, Hiromi, Sakawaki, Tomoyuki, Miura, David I, Watkins, Tetsuro, Matano
Publikováno v:
Molecular therapy : the journal of the American Society of Gene Therapy. 30(5)
Effective T cell induction is an important strategy in HIV-vaccine development. However, it has been indicated that vaccine-induced HIV-specific CD4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c89516dc65fcdf22f9970740e56aa38f
https://pubmed.ncbi.nlm.nih.gov/35231604
https://pubmed.ncbi.nlm.nih.gov/35231604
Autor:
Yuki Ishida, Tomoyuki Miura, Kanako Matsuura, Minako Kikukawa, Hiromi Sakawaki, Hiromi Mori, Ai Himeno
Publikováno v:
Archives of Virology. 164:1297-1308
We previously developed CCR5-tropic neutralization-resistant simian/human immunodeficiency virus (SHIV) strains and a rhesus macaque model of infection with these SHIVs. We induced the production of neutralizing antibodies (nAbs) against HIV-1 by inf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f6de83ef7fe4df771b6f7c1e5666984
https://doi.org/10.1007/s00705-019-04173-5
https://doi.org/10.1007/s00705-019-04173-5
Autor:
Shoichi Sakaguchi, Juri Suzuki, Hiromi Sakawaki, Tadashi Isa, So Nakagawa, Munehiro Okamoto, Rie Koide, Rokusuke Yoshikawa, Tomoyuki Miura, Takayuki Miyazawa
Publikováno v:
Journal of General Virology. 100:266-277
Recently, a large number of Japanese macaques (Macaca fuscata) died of an unknown hemorrhagic syndrome at Kyoto University Primate Research Institute (KUPRI) and an external breeding facility for National Institute for Physiological Sciences (NIPS).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5047b80986ec4b8677efc6ba4ebbe872
https://doi.org/10.1099/jgv.0.001199
https://doi.org/10.1099/jgv.0.001199
Autor:
Makoto Kuroda, Vanessa M. Hirsch, Hiromi Sakawaki, Shuzo Matsushita, Hiroyuki Yamamoto, Takeo Kuwata, Mikiko Shimizu, Midori Okazaki, Yohei Seki, Tomoyuki Miura, Hirofumi Akari, Tsuyoshi Sekizuka, Akatsuki Saito, Hiroshi Ishii, Masato Sano, Saori Matsuoka, Tetsuro Matano
Publikováno v:
J Virol
Virus infection induces B cells with a wide variety of B-cell receptor (BCR) repertoires. Patterns of induced BCR repertoires are different in individuals, while the underlying mechanism causing this difference remains largely unclear. In particular,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::177f0a5f7ad1b8b71676ec43cf950b6a
https://doi.org/10.1128/jvi.02455-20
https://doi.org/10.1128/jvi.02455-20
Autor:
Kaho Matsumoto, Hiromi Sakawaki, Takeo Kuwata, Tomoyuki Miura, Nami Ohashi, Hirokazu Tamamura, Kohei Takahashi, Kohei Tsuji, Shuzo Matsushita, Tingting Yang, Ai Himeno, Ami Masuda, Kiju Konno, Shigeyoshi Harada, Takuya Kobayakawa, Kazuhisa Yoshimura, Yusuke Ishida
Publikováno v:
Journal of medicinal chemistry. 64(3)
CD4 mimics are small molecules that inhibit the interaction of gp120 with CD4. We have developed several CD4 mimics. Herein, hybrid molecules consisting of CD4 mimics with a long alkyl chain or a PEG unit attached through a self-cleavable linker were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cb0a781d060d491c30991eda7c69501
https://pubmed.ncbi.nlm.nih.gov/33497209
https://pubmed.ncbi.nlm.nih.gov/33497209
Autor:
Naofumi Takahashi, Takushi Nomura, Yusuke Takahara, Hiroyuki Yamamoto, Teiichiro Shiino, Akiko Takeda, Makoto Inoue, Akihiro Iida, Hiroto Hara, Tsugumine Shu, Mamoru Hasegawa, Hiromi Sakawaki, Tomoyuki Miura, Tatsuhiko Igarashi, Yoshio Koyanagi, Taeko K Naruse, Akinori Kimura, Tetsuro Matano
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e54300 (2013)
Several major histocompatibility complex class I (MHC-I) alleles are associated with lower viral loads and slower disease progression in human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) infections. Immune-correlates analyses
Externí odkaz:
https://doaj.org/article/4c1ed36a0cbb4162b3cc4ee284299b33
Autor:
Tomoyuki Miura, Saori Matsuoka, Midori Nakamura-Hoshi, Tetsuro Matano, Tsuyoshi Tokusumi, Sayuri Seki, Takushi Nomura, Yusuke Takahara, Hiroshi Ishii, Tsugumine Shu, Hiromi Sakawaki, Hiroyuki Yamamoto
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Anti-retroviral therapy (ART) can inhibit HIV proliferation but not achieve virus eradication from HIV-infected individuals. Under ART-based HIV control, virus-specific CD8+ T-cell responses are often reduced. Here, we investigated the impact of ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6a3a067cae6df8923ec97461f5e7cd6
https://doi.org/10.1038/s41598-020-68267-w
https://doi.org/10.1038/s41598-020-68267-w