Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Hiromasa Takashima"'
Autor:
Ryuichi Ono, Makiko Kuwagata, Mie Naruse, Akihito Watanabe, Masao Takano, Takuro Hasegawa, Hiromasa Takashima, Yusuke Yoshioka, Takahiro Ochiya, Yoko Hirabayashi, Satoshi Kitajima
Publikováno v:
Fundamental Toxicological Sciences; 2024, Vol. 11 Issue 1, p37-56, 20p
Autor:
Makiko Shimizu, Hiromasa Takashima, Takuro Hasegawa, Satoshi Kitajima, Makiko Kuwagata, Hiroshi Yamazaki
Publikováno v:
The Journal of Toxicological Sciences. 46:553-560
The teratogenicity of the chemotherapeutic drug thalidomide is species-specific and affects humans, non-human primates, and rabbits. The primary oxidation of thalidomide in previously investigated rodents predominantly resulted in the formation of de
Autor:
Akihiko Hirose, Hiromasa Takashima, Atsushi Ono, Kazuo Ushida, Toshime Igarashi, Takako Iso, Kaoru Inoue, Michihito Takabe, Tomoko Kawamura, Hiroshi Suzuki, Mariko Matsumoto, Shihori Tanabe, Takashi Yamada
Publikováno v:
Regulatory Toxicology and Pharmacology. 100:105-117
Benzyl salicylate is used as a fragrance ingredient and an ultraviolet light absorber, but its toxicity is unknown. Therefore, toxicity tests and hazard classification were conducted for screening assessment under the Japanese Chemical Substances Con
Autor:
Shimpei Kajita, Kanata Ibi, Hiromasa Takashima, Toshiki Matsuoka, Yumi Sakai, Yoji Miwa, Mika Senuma, Tohru Uesugi, Masao Horimoto, Tatsuya Shimizu, Michio Fujiwara, Ken-ichi Noritake, Shino Nishizawa, Takayuki Hirano, Makiko Kuwagata, Masayuki Ube, Akihito Yamashita, Yuka Kirihata, Taishi Tateishi, Satoshi Kudo, Ryu-ichi Katagiri, Kaoru Yabe, Sho Tanaka, Takafumi Oota, Hitoshi Hojo, Nao Nakano, Terumasa Taniguchi, Yuko Sakai, Makoto Ema, Hiroshi Mineshima
Publikováno v:
Congenital anomalies. 59(4)
Historical control data from prenatal developmental toxicity studies in rats have been used to evaluate whether toxicology outcomes were induced by exposure to a chemical or were within the range of spontaneous variation. These data are also importan
Autor:
Syunji Yokota1 yokota.s@fdsc.or.jp, Hiromasa Takashima1, Ryo Ohta2, Yoshiaki Saito3, Takashi Miyahara1, Yuka Yoshida1, Tsukasa Negura1, Mika Senuma1, Kenji Usumi, Naoyuki Hirabayashi4, Takaho Watanabe4, Shinji Horiuchi5, Yuji Fujitani6, Seishiro Hirano6, Hidekazu Fujimaki6
Publikováno v:
Journal of Toxicological Sciences. Jun2011, Vol. 36 Issue 3, p267-276. 10p.
Autor:
Hiromasa Takashima, Atsushi Ono, Akihiko Hirose, Kazuhito Yokoyama, Mutsuko Hirata-Koizumi, Mariko Matsumoto, Makiko Yamaguchi, Hina Kato, Yuka Yoshida, Tomoko Kawamura, Mika Takahashi, Mika Senuma
Publikováno v:
Food and Chemical Toxicology. 56:290-296
A 28-day repeated dose toxicity test and reproduction/developmental toxicity test for N,N'-diphenyl-p-phenylenediamine (DPPD) were conducted in [Crl:CD(SD)] SPF rats. Male and female rats were dosed with DPPD by gavage for 28 days at 0, 100, 300, or
Autor:
Shigeru Hisada, Hiromasa Takashima, Takashi Ikeda, Keiichi Ito, Yoji Miwa, Mika Senuma, Ken-ichi Noritake, Eiji Maki, Taishi Tateishi
Publikováno v:
The Journal of Toxicological Sciences. 38:847-854
The purpose of the present study was to collect the background data on Wistar Hannover [Crl:WI(Han)] (hereafter Wistar Han) rats in embryo-fetal development studies from the 6 safety research facilities of pharmaceutical companies and contract resear
Autor:
Shoji Takeda, Akio Tanaka, Tetsunari Nishikawa, Koichi Imai, Tsukasa Akasaka, Hiromasa Takashima, Akito Tanoue, Kazuhiko Suese, Fumio Watari, Kazuaki Nakamura
Publikováno v:
Applied Surface Science. 258:8444-8447
The effects of nanomaterials on human reproduction and development remain unknown. The risks of nanomaterials for future generations should be elucidated. Thus, it is important to establish an experimental method to accurately examine embryotoxicity.
Autor:
Shinji Horiuchi, Mika Senuma, Takaho Watanabe, Hiromasa Takashima, Seishiro Hirano, Takashi Miyahara, Kenji Usumi, Naoyuki Hirabayashi, Yuji Fujitani, Syunji Yokota, Yuka Yoshida, Ryo Ohta, Hidekazu Fujimaki, Yoshiaki Saito, Tsukasa Negura
Publikováno v:
The Journal of Toxicological Sciences. 36:267-276
In the present study, in order to reveal novel adverse effects of ultrafine particles (UFP) on the central nervous system, the effects of nanoparticle-rich diesel exhaust particles (NRDEP; count mode diameter, 21.45 nm) on emotional behavior, learnin
Publikováno v:
Sensors and Actuators B: Chemical. 77:190-195
A solid state electrochemical sensing device using stabilized-zirconia has been made by thick-film lamination. The sensing properties of the sensor have been investigated. As a result, the sensor could be miniaturized and improved in the respect of t