Zobrazeno 1 - 10 of 48 pro vyhledávání: '"Hiromasa Mori"'
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Akademický článek
Quantifying the Benefits of Digital Biomarkers and Technology-Based Study Endpoints in Clinical Trials: Project Moneyball
Autor: Hiromasa Mori, Stig Johan Wiklund, Jason Yuren Zhang
Publikováno v: Digital Biomarkers, Vol 6, Iss 2, Pp 36-46 (2022)
Introduction: Digital biomarkers have significant potential to transform drug development, but only a few have contributed meaningfully to bring new treatments to market. There are uncertainties in how they will generate quantifiable benefits in clin
Externí odkaz: https://doaj.org/article/6d0d14bc0b6a49379c5fc0da28bea809
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Cilostazol prevents amyloid β peptide25-35-induced memory impairment and oxidative stress in mice
Autor: Hiromasa Mori, Masayuki Hiramatsu, Aki Nishiyama, Osanao Takiguchi
Publikováno v: British Journal of Pharmacology. 161:1899-1912
BACKGROUND AND PURPOSE Cilostazol may be effective in dementia associated with a cerebral ischaemia. In this study, we examined whether it exerts beneficial effects on learning and/or memory impairment induced by Aβ25-35 in mice, and compared its ef
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f87f2546327a1eeb792d0403e6521ff1
https://doi.org/10.1111/j.1476-5381.2010.01014.x
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Dependence of Hydrolysis of .BETA.-Lactams with a Zinc(II)-.BETA.-Lactamase Produced from Serratia marcescens (IMP-1) on pH and Concentration of Zinc(II) Ion: Dissociation of Zn(II) from IMP-1 in Acidic Medium
Autor: Kumiko Harada, Hiromasa Mori, Yoshihiro Yamaguchi, Akiko Kawanami, Hitoshi Nakayama, Hisami Yasuzawa, Shiho Mifune, Masafumi Goto, Yoshichika Arakawa, Toshihiro Higashi
Publikováno v: Biological and Pharmaceutical Bulletin. 26:589-594
The pH dependence for the hydrolysis of beta-lactam antibiotics by a metallo-beta-lactamase (IMP-1) produced from Serratia marcescens was investigated varying the concentration of Zn(II). The activity of IMP-1 for imipenem was decreased at pH less th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c2e6a45f4e6b90b46451bda8124deaa
https://doi.org/10.1248/bpb.26.589
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Preparation of Ternary Platinum(II) Complexes with N-(.OMEGA.-Phenylalkyl)-1,2-ethanediamine and 2,2'-Dipyridine and the Effect of the Methylene Chain Length of the N-(.OMEGA.-Phenylalkyl)-1,2-ethanediamine in the Complexes on Intermolecular Interactions with Various Arylsulfonates
Autor: Masafumi Goto, Hiromasa Kurosaki, Masamitsu Sumimoto, Hiromasa Mori, Katsutoshi Tanaka
Publikováno v: Chemical and Pharmaceutical Bulletin. 51:649-653
A series of ternary complexes comprised of platinum(II), 2,2'-dipyridine, and N-(omega-phenylalkyl)-1,2-ethanediamine was prepared by varying the number (n) of methylene chain carbons between the phenyl group and one of the amino groups of 1,2-ethane
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0459917b12509e61df5f65edceb61f1b
https://doi.org/10.1248/cpb.51.649
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8
CO2 reforming of waste plastics
Autor: Hiroshi Yamada, Tomohiko Tagawa, Hiromasa Mori
Publikováno v: Journal of Industrial and Engineering Chemistry. 16:7-9
Carbon dioxide reforming of polyethylene was carried out. Pyrolysis and catalytic carbon dioxide reforming were combined. Polyethylene was packed at the bottom of the reactor and the catalyst, Pd/Al 2 O 3 , was packed at the top of the reactor. The p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::237bc2e5a2eb745f90c80c7ad65e7df2
https://doi.org/10.1016/j.jiec.2010.01.029
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Reversion of muscarinic autoreceptor agonist-induced acetylcholine decrease and learning impairment by dynorphin A (1-13), an endogenous κ-opioid receptor agonist
Autor: Hiromasa Mori, Hiroyasu Murasawa, Masayuki Hiramatsu, Tsutomu Kameyama
Publikováno v: British Journal of Pharmacology. 123:920-926
1 We investigated whether carbachol, a muscarinic receptor agonist, induces learning and memory impairment, and if so, dynorphin A (1–13), an endogenous κ-opioid receptor agonist, ameliorates the impairment of learning and memory induced by carbac
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8e464ca06616e92fb6d96eb567f0fdd7
https://doi.org/10.1038/sj.bjp.0701671
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