Zobrazeno 1 - 10 of 14 pro vyhledávání: '"Hirokuni Tamatsu"'
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In Vivo and In Vitro Assessment of the Cardiovascular Effects of 8-(Benzylthio)-N6-n-Butyl–Cyclic AMP
Autor: Mikio Nakazawa, Keisuke Takeda, Kazuki Matsui, Yoshito Nakagawa, Takahito Kimura, Hirokuni Tamatsu, Hajime Nakahara, Tomie Kawada, Shoichi Imai
Publikováno v: Journal of Cardiovascular Pharmacology. 7:862-868
In the canine heart-lung preparation (HLP) and the anesthetized open-chest dog, both 8-(Benzylthio)-N6-n-butyl-cyclic AMP (BTB-cyclic AMP) (10 times more potent) and dibutyryl-cyclic AMP (DB-cyclic AMP) produced a definite positive inotropic effect (
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d07be0430b0db79a6650d649a50ba97
https://doi.org/10.1097/00005344-198509000-00008
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3
Effects of drugs on the cerebral circulation of the dog in relation to the cerebral oxygen consumption
Autor: Hirokuni Tamatsu, Ushio Nakano, Keisuke Takeda, Shoichi Imai, Wan-Pao Chin, Toyohiko Ushijima
Publikováno v: British journal of pharmacology. 79(4)
Drug effects were studied on the cerebral circulation by measuring the sagittal sinus outflow in the anaesthetized dog following the method of Michenfelder and by monitoring cerebral oxygen consumption. Systemic aortic pressure, heart rate and spinal
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bf46b09403da856ae6da0c3820a0d0e
https://pubmed.ncbi.nlm.nih.gov/6418251
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4
Anti-arrhythmic effects of (-)-carnitine chloride and its acetyl analogue on canine late ventricular arrhythmia induced by ligation of the coronary artery as related to improvement of mitochondrial function
Autor: Kazuki Matsui, Mikio Nakazawa, Naoki Takatsuka, Hirokuni Tamatsu, Keisuke Takeda, Shoichi Imai
Using the two-stage coronary ligation method, first described by Harris, (1950), anti-arrhythmic effects (AAE) of (-)-carnitine chloride (LCC) and acetyl (-)-carnitine chloride (ALCC) were studied in conscious unrestrained dogs in comparison with tho
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4707244038f2929e585ab1e5007583c4
https://europepmc.org/articles/PMC1987033/
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5
Inhibition by Thiamine Tetrahydrofurfuryl Disulfide (TTFD) of the Arachidonic Acid Cascade-Line Activation as Evidenced in the Heart-Lung Preparation of the Dog
Autor: Mikio Nakazawa, Hiroshi Watanabe, Hiroto Matsuda, Yoshito Nakagawa, Shoichi Imai, Hirokuni Tamatsu, Hajime Nakahara, Kazuki Matsui
Publikováno v: Japanese Journal of Pharmacology. 39:375-376
The effects of thiamine tetrahydrofurfuryl disulfide (TTFD) on the gradual increase in the coronary blood flow (CBF) inherent in the canine heart-lung preparation were studied. TTFD is a disulfide-type derivative of thiamine reported to have an antii
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43dd98aec2ff7d0da610095a1d4a811e
https://doi.org/10.1254/jjp.39.375
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9
31P-NMR study on myocardial energy metabolism. (3) Application of saturation transfer technique
Autor: Hirokuni Tamatsu, Shoichi Imai, Mikio Nakazawa
Publikováno v: Japanese Journal of Pharmacology. 33:77
The kinetics of creatine kinase (CK) was determined with saturation transfer technique in vitro. The modified Bloch equations for CK reaction are: dM/dt=(Mo-M)/T1-KM+K’M’, where Mo is the equilibrium creatine phosphate (CP) magnetization without
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::542db13640bf38214023b45c1563812e
https://doi.org/10.1016/s0021-5198(19)60288-x
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