Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Hiroko Yokoe"'
Autor:
Ileana Zucchi, Alberto Albertini, Rolland Reinbold, Jonathan Auerbach, Gianfranco Bellipanni, Miranda Yang, Marianna Greco, Joel Jessee, Valentina Martino, Alice E. Chen, Manickam Pachiappan, James Kehler, Antonio Giordano, Luciano Milanesi, Martin Götte, Hiroko Yokoe
Publikováno v:
Journal of Cellular Physiology. 232:1262-1269
Cellular reprogramming by epigenomic remodeling of chromatin holds great promise in the field of human regenerative medicine. As an example, human-induced Pluripotent Stem Cells (iPSCs) obtained by reprograming of patient somatic cells are sufficient
Autor:
Abelardo Silva, John W. Erickson, Betty Yu, Sergei V. Gulnik, Elena Afonina, Michael Eissenstat, Hiroko Yokoe, Tanya Guerassina, Douglas Ludtke
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 22:5078-5083
We have designed and synthesized a series of HIV protease inhibitors (PIs) with enamino-oxindole substituents optimized to interact with the S2' subsite of the HIV protease binding pocket. Several of these inhibitors have sub-nanomolar K(i) and antiv
Autor:
Robert R. H. Anholt, Hiroko Yokoe
Publikováno v:
Proceedings of the National Academy of Sciences. 90:4655-4659
The extracellular mucous matrix of olfactory neuroepithelium is a highly organized structure in intimate contact with chemosensory cilia that house the olfactory transduction machinery. Here we describe the molecular cloning and primary structure of
Autor:
Joel Jessee, Julie R. Escamilla-Powers, Brea Midthune, Anton P. McCaffrey, Alexandre Lebedev, Dongwon Shin, Richard I. Hogrefe, Hiroko Yokoe, Krist T. Azizian
Publikováno v:
Molecular Therapy. 23:S259
Recently, there has been significant interest in the use of messenger RNA (mRNA) based expression systems for gene therapy applications. Several groups have shown that mRNA is an attractive vehicle for therapeutic gene expression in mammals (Kormann
Autor:
Peng Liu, Michael B. Knable, Vinod Charles, Maree J. Webster, Hiroko Yokoe, C. Anthony Altar, Andrew L. Lemire, Yury V. Bukhman, Linda W. Jurata, Jeffrey Bullard, Jeffrey A. Brockman, Theresa A. Young
Publikováno v:
Biological psychiatry. 58(2)
Background Hippocampal dentate granule neurons are altered in schizophrenia, but it is unknown if their gene expressions change in schizophrenia or other psychiatric diseases. Methods Laser-captured dentate granule neurons from two groups of schizoph
Autor:
Hiroko Yokoe, Tobias Meyer
Publikováno v:
Nature biotechnology. 14(10)
We describe a method of monitoring the spatial dynamics of proteins in intact cells by locally enhancing the blue excited fluorescence of green fluorescent protein (GFP) using a spatially focused ultraviolet-laser pulse. GFP fusion proteins were effi
Autor:
Nancy L. Allbritton, Hiroko Yokoe, Michael Kuhn, Eva Reinhard, Kenneth R. Niebling, Tobias Meyer
Publikováno v:
Developmental biology. 170(1)
Activation of the phosphoinositide (PI) pathway has been shown to be involved in the compaction of blastomeres in mouse embryos and in embryonic axis formation in Xenopus and in zebrafish embryos. Here we investigate Ca2+ signals in individual blasto
Publikováno v:
Biochemistry. 30(38)
We have identified a novel glycoprotein expressed exclusively in frog olfactory neuroepithelium, which we have named "olfactomedin". Olfactomedin is a 57-kDa glycoprotein recognized by seven monoclonal antibodies, previously shown to react solely wit
Publikováno v:
Cell Structure and Function. 12:83-91
Phagocytosis of microspheres in V79 Chinese hamster lung cells was investigated by flow cytometry. Fluorescent microspheres (1.8 micron diameter) were used as the ingesta. Change in the number of V79 cells containing fluorescent microspheres was meas