Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Hiroko Toyota"'
Autor:
Wataru Nishi, Ei Wakamatsu, Hiroaki Machiyama, Ryohei Matsushima, Kensho Saito, Yosuke Yoshida, Tetsushi Nishikawa, Tomohiro Takehara, Hiroko Toyota, Masae Furuhata, Hitoshi Nishijima, Arata Takeuchi, Miyuki Azuma, Makoto Suzuki, Tadashi Yokosuka
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract With recent advances in immune checkpoint inhibitors (ICIs), immunotherapy has become the standard treatment for various malignant tumors. Their indications and dosages have been determined empirically, taking individually conducted clinical
Externí odkaz:
https://doaj.org/article/504d7a530e5c44459a41bf162dcb82a0
Autor:
Wataru Nishi, Ei Wakamatsu, Hiroaki Machiyama, Ryohei Matsushima, Kensho Saito, Yosuke Yoshida, Tetsushi Nishikawa, Tomohiro Takehara, Hiroko Toyota, Masae Furuhata, Hitoshi Nishijima, Arata Takeuchi, Miyuki Azuma, Makoto Suzuki, Tadashi Yokosuka
With recent advances in immune checkpoint inhibitors (ICIs), cancer immunotherapy has become the standard treatment for various malignant tumors. Their indications and dosages have been determined on the basis of several clinical trials conducted sep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dcacfd973d2ef0ea901fd9744239b7be
https://doi.org/10.21203/rs.3.rs-1945681/v1
https://doi.org/10.21203/rs.3.rs-1945681/v1
Publikováno v:
Abstracts of the ICA. 1:1-2
This report searches for the Japanese view of beauty and nature through a study of the mapping of the transformation of a mountain’s shape. A normal map primarily intends to express existing shapes, but this report maps the vanished shape of a moun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b95839c91fb43b3ba4287ecae79c0b65
https://doi.org/10.5194/ica-abs-1-368-2019
https://doi.org/10.5194/ica-abs-1-368-2019
Autor:
Katsuko Sudo, H. Iobe, T. Nagao, Terutaka Kakiuchi, Hiroko Toyota, Noriko Yanase, Taku Kuwabara, R. H. Takahashi, Junichiro Mizuguchi, K. Kojima
Publikováno v:
Apoptosis. 20:444-454
Apoptotic cell death plays a pivotal role in the development and/or maintenance of several tissues including thymus. Deregulated thymic cell death is associated with autoimmune diseases including experimental autoimmune encephalomyelitis (EAE), a pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44a42210a19b23e596b1606f2f42c3f8
https://doi.org/10.1007/s10495-014-1082-0
https://doi.org/10.1007/s10495-014-1082-0
Autor:
Hiroko Toyota, Junichiro Mizuguchi, Noriko Yanase, Mitsunori Harada, Takayuki Yoshimoto, Yasuki Kato
Publikováno v:
Oncology Reports. 33:292-296
Immunotherapy has gained special attention due to its specific effects on tumor cells and systemic action to block metastasis. We recently demonstrated that ovalbumin (OVA) conjugated to the surface of nanoparticles (NPs) (OVA‑NPs) can manipulate h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71cee5f8f3c438ad0bfe026a1d1390b7
https://doi.org/10.3892/or.2014.3603
https://doi.org/10.3892/or.2014.3603
Autor:
Yasuki Kato, Takahiro Seki, Kikumi Hata, Hiroko Toyota, Mitsunori Harada, Noriko Yanase, Seina Yagyu, Junichiro Mizuguchi
Publikováno v:
Vaccine. 32:5918-5924
There is an urgent requirement for a novel vaccine that can stimulate immune responses without unwanted toxicity, including IgE elevation. We examined whether antigen ovalbumin (OVA) conjugated to the surface of nanoparticles (NPs) (OVA-NPs) with ave
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::753deba267871883773152786bd79cfc
https://doi.org/10.1016/j.vaccine.2014.08.059
https://doi.org/10.1016/j.vaccine.2014.08.059
Autor:
Kikumi Hata, Mohamed El Sherif Gadelhaq Badr, Tadashi Yokosuka, Masae Furuhata, Hiroko Toyota
Publikováno v:
Chronic Inflammation ISBN: 9784431560661
Properly functioning T cells should clear invading pathogens and tumors without causing damage to the host. Programmed cell death-1 (PD-1) is a negative costimulatory receptor that is expressed on an effector T cell to regulate its functions; otherwi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85fc413ad059e1d210e5537419c66d16
https://doi.org/10.1007/978-4-431-56068-5_34
https://doi.org/10.1007/978-4-431-56068-5_34
Autor:
Hiroko Toyota, Junichiro Mizuguchi, Kengo Yamamoto, Takashi Koyama, Atsuhiro Imakiire, Takaaki Koyama, Takashi Mikami
Publikováno v:
Journal of Orthopaedic Research. 24:1153-1162
Molecular mechanisms underlying chemotherapeutic agent–induced apoptosis in sarcoma cells are not well known. Induction of apoptosis is regulated by several components including mitogen-activated protein kinases (MAPKs) comprising ERK, p38MAPKs, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1dded0d5d9bc4254c9af9a0e69f1cd9
https://doi.org/10.1002/jor.20176
https://doi.org/10.1002/jor.20176
Autor:
Hiroko Toyota1 s1630022@u.tsukuba.ac.jp, Daiki Ito1 likefrontier_1590@yahoo.co.jp, Shuya Suzuki1 mk350s1102@gmail.com, Ryohei Hara1 miyako.higawa@me.com, Wang Junxiang1 junxiang602@qq.com
Publikováno v:
Abstracts of the ICA. 2019, Vol. 1, p1-2. 2p.
Autor:
Satoshi Mohri, Gentaro Iribe, Hiroyuki Suga, Hiroshi Okuyama, Katsuhiko Tsujioka, Fumihiko Kajiya, Hiroko Toyota, Junichi Araki, Juichiro Shimizu, Kazufumi Nakamura, Naoto Yagi
Publikováno v:
Pfl�gers Archiv European Journal of Physiology. 448:153-160
We examined the sarcomere length-dependence of the spacing of the hexagonal lattice of the myofilaments and the mass transfer of myosin cross-bridges during contraction of right ventricular papillary muscle of the rat. The lattice spacing and mass tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::306b99592c53be5294fa0028c9db19bc
https://doi.org/10.1007/s00424-004-1243-z
https://doi.org/10.1007/s00424-004-1243-z