Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Hiroko Toriniwa"'
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0150213 (2016)
An inactivated Japanese encephalitis virus (JEV) vaccine, which induces neutralizing antibodies, has been used for many years in Japan. In the present study, the JEV prM-E protein gene was cloned, inserted at the P/M junction of measles AIK-C cDNA, a
Externí odkaz:
https://doaj.org/article/ab3ebc5921fe422e91ea1c6085621466
Publikováno v:
The Journal of Veterinary Medical Science
Thirty-seven specimens of wild boar sera were collected from August 2016 to March 2018 in Ishikawa prefecture, Japan. Thirty-two specimens (86.5%) were positive for neutralizing antibodies against Japanese encephalitis virus (JEV). Eight specimens (2
Autor:
Kayoko Hayakawa, Keiji Nakamura, Satoshi Kutsuna, Maki Nagashima, Takato Nakamoto, Hiroko Toriniwa, Tomoyoshi Komiya, Toshihiro Matsui, Norio Ohmagari, Kei Yamamoto
Publikováno v:
Am J Trop Med Hyg
In July 2018, acute Q fever (AQF) was diagnosed in two Japanese individuals from the same family. They returned to Japan from Malawi, where the epidemiology of AQF is unknown. A child presented to the hospital with high-grade fever without any sympto
Autor:
Hiroko Toriniwa, Tomoyoshi Komiya
Publikováno v:
Vaccine. 29:1859-1862
We produced a Vero cell-derived inactivated Japanese encephalitis vaccine using a serum-free medium, as a substitute for the conventional mouse brain-derived Japanese encephalitis vaccine. The immunogenicity of this cell-derived vaccine was higher th
Autor:
Tomoyoshi Komiya, Hiroko Toriniwa
Publikováno v:
Vaccine. 26:3680-3689
We established a method of producing a Vero cell-derived Japanese encephalitis vaccine using serum-free medium, and tested its stability using various stabilizers during the inactivation process and storage at 4 degrees C and 28 degrees C. Similar to
Recombinant Measles AIK-C Vaccine Strain Expressing the prM-E Antigen of Japanese Encephalitis Virus
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 3, p e0150213 (2016)
PLoS ONE, Vol 11, Iss 3, p e0150213 (2016)
An inactivated Japanese encephalitis virus (JEV) vaccine, which induces neutralizing antibodies, has been used for many years in Japan. In the present study, the JEV prM-E protein gene was cloned, inserted at the P/M junction of measles AIK-C cDNA, a
Autor:
Hiroko Toriniwa, Katsuya Hirai, Yasuyuki Arakawa, Tomoyoshi Komiya, Hideto Fukushi, Yasutomo Arashima, Kimitoshi Kato, Kenji Sadamasu
Publikováno v:
Journal of Infection and Chemotherapy. 9:151-155
The source of Q fever infection, was investigated by serological and polymerase chain reaction (PCR) analysis of specimens from humans and pets in an animal hospital. Two animal health technicians showed a positive serological reaction against Coxiel
Autor:
Hiroko Toriniwa, Nikolai Petrovsky, Peter D. Cooper, Mario Lobigs, Roy A. Hall, Tomoyoshi Komiya, Megan Pavy, Päivi Lobigs
Publikováno v:
The Journal of General Virology
Advax is a polysaccharide-based adjuvant that potently stimulates vaccine immunogenicity without the increased reactogenicity seen with other adjuvants. This study investigated the immunogenicity of a novel Advax-adjuvanted Vero cell culture candidat
Autor:
Tomoyoshi Komiya, Hiroko Toriniwa
Publikováno v:
Biologicals : journal of the International Association of Biological Standardization. 35(4)
A novel oscillating bioreactor, BelloCell, was successfully applied for the cultivation of Vero cells using serum-free medium, and the production of Japanese encephalitis virus. The BelloCell requires no air sparging, pumping, or agitation, and thus
Autor:
Hiroko Toriniwa, Tomoyoshi Komiya
Publikováno v:
Microbiology and immunology. 50(5)
We established a rapid, quantitative real-time reverse transcription loop-mediated isothermal amplification (RT-LAMP) assay targeting the envelope gene of Japanese encephalitis virus. The RT-LAMP enabled us to detect the target product within 1 hr by