Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Hiroko Tamura"'
Publikováno v:
The Journal of Biochemistry. 170:623-629
A substantial body of work has been carried out describing the structural features of the complex between single-domain antibodies (VHHs) and antigens, and the preeminence for epitopes located at concave surfaces of the antigen. However, the thermody
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3e803e739f1fcdeef0e747b57ba69d5
https://doi.org/10.1093/jb/mvab082
https://doi.org/10.1093/jb/mvab082
Autor:
Hiroko Shibata, Toru Tanaka, Hiroko Tamura, Akiko Ishii-Watabe, Terao Yosuke, Jose M. M. Caaveiro, Seigo Oe, Teruhiko Ide, Akira Harazono, Satoru Nagatoishi, Noritaka Hashii, Daisuke Kuroda, Kouhei Tsumoto, Koldo Morante, Minoru Tada, Masato Kiyoshi
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Scientific Reports
Scientific Reports
The N-glycan moiety of IgG-Fc has a significant impact on multifaceted properties of antibodies such as in their effector function, structure, and stability. Numerous studies have been devoted to understanding its biological effect since the exact co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fa398c9e3ed9a642d045279e179692a
http://link.springer.com/article/10.1038/s41598-018-22199-8
http://link.springer.com/article/10.1038/s41598-018-22199-8
Autor:
Takuro Kanekura, Youhei Uchida, Aoi Okubo, Kazuyasu Fujii, Hiroko Tamura, Hirosaka Inoue, Maiko Hayashida, Kenji Ishitsuka
Publikováno v:
The Journal of Dermatology. 46
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53ca10f326b51dddc0b632f263322c12
https://doi.org/10.1111/1346-8138.15019
https://doi.org/10.1111/1346-8138.15019
Autor:
Hiroko Tamura, Kouhei Tsumoto, Hiroki Akiba, Kenji Sugase, Jose M. M. Caaveiro, Masato Kiyoshi, Saeko Yanaka
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Single-domain antibodies (VHHs or nanobodies), developed from heavy chain-only antibodies of camelids, are gaining attention as next-generation therapeutic agents. Despite their small size, the high affinity and specificity displayed by VHHs for anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c3473093666eec961c0c8479c0e8460
http://hdl.handle.net/2433/250074
http://hdl.handle.net/2433/250074
Publikováno v:
Protein engineering, designselection : PEDS. 32(9)
Computer-guided library generation is a plausible strategy to optimize antibodies. Herein, we report the improvement of the affinity of a single-domain camelid antibody for its antigen using such approach. We first conducted experimental and computat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ca98c96ee35f1dccfcb78351a2efa24
https://pubmed.ncbi.nlm.nih.gov/32167147
https://pubmed.ncbi.nlm.nih.gov/32167147
Autor:
Yasuo Shichinohe, Kyoko Kurome, Hiroko Tamura, Yoshihito Ujike, Yoshimasa Tsushima, Yoshio Okamoto
Publikováno v:
Nihon Kyukyu Igakukai Zasshi. 21:943-950
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c4e122cc13e6fb4e15c54af1a7ea900
https://doi.org/10.3893/jjaam.21.943
https://doi.org/10.3893/jjaam.21.943
Autor:
Hiroko Tamura
Publikováno v:
Journal of Architecture and Planning (Transactions of AIJ). 67:107-113
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f56dc7e59a529215fcc58dd8d689ec06
https://doi.org/10.3130/aija.67.107_1
https://doi.org/10.3130/aija.67.107_1
Publikováno v:
The Japanese Journal of Nutrition and Dietetics. 50:237-244
横浜宮崎脳神経外科病院入院患者において, 成分栄養剤ED-ACによる高濃度投与を試み, 下痢などの臨床症状を観察し, 血液生化学検査による栄養アセスメントを指標にした検討を行った。
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cfd6e4bd638025a1e742efec0e024dd7
https://doi.org/10.5264/eiyogakuzashi.50.237
https://doi.org/10.5264/eiyogakuzashi.50.237
Autor:
Yuhki Yamaguchi, Satoyoshi Yamashita, Noriyoshi Kusano, Chieko Suzuki, Masaaki Masuhara, Kiwamu Okita, Fujio Murakami, Kouji Tanigawa, Hiroko Tamura
Publikováno v:
Journal of gastroenterology. 33(3)
A 34-year-old man diagnosed with fulminant hepatitis, caused by hepatitis B virus, and acute renal failure was referred to our hospital. After admission to the intensive care unit, the liver and renal failure were ameliorated. Melena requiring transf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d0d1b5f51fa496918a02d775ee9a8ac
https://pubmed.ncbi.nlm.nih.gov/9658323
https://pubmed.ncbi.nlm.nih.gov/9658323
Autor:
Masatomo Tanabe, Hiroko Tamura
Publikováno v:
The Japanese Journal of Special Education. 26:43-52
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ddf876f09aaf3514ae1026f32946840b
https://doi.org/10.6033/tokkyou.26.43_1
https://doi.org/10.6033/tokkyou.26.43_1