Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Hiroko Sugawara"'
Autor:
Hiroko Sugawara, Akitoshi Date, Satoshi Fuke, Yutaka Nakachi, Tadafumi Kato, Minoru Narita, Miki Bundo, Kazuya Iwamoto
Publikováno v:
Neuropsychopharmacology Reports, Vol 44, Iss 1, Pp 250-255 (2024)
Abstract Quantifying cytosine modifications in various brain regions provides important insights into the gene expression regulation and pathophysiology of neuropsychiatric disorders. In this study, we quantified 5‐methylcytosine (5‐mC), 5‐hydr
Externí odkaz:
https://doaj.org/article/53b7f10946cf406ea9605263937b23d6
Publikováno v:
Frontiers in Psychiatry, Vol 15 (2024)
Depressive episodes with psychotic symptoms are prevalent among the older adults, emphasizing the need to differentiate them from dementia with Lewy bodies (DLB), in which depressive and psychotic symptoms commonly coexist. In contrast, psychotic sym
Externí odkaz:
https://doaj.org/article/b4c940da237a43798666d166970bbe65
Autor:
Fumito Hamada, Hikaru Hori, Hitoshi Iida, Hiroyuki Yokoyama, Hiroko Sugawara, Akito Hatanaka, Leo Gotoh, Muneaki Ogata, Hiroki Kumagai, Rika Yano, Yuko Tomiyama, Tetsuya Yoshida, Yoshimi Yamaguchi, Ryo Asada, Masato Masuda, Yuta Okamoto, Hiroaki Kawasaki
Publikováno v:
Metabolites, Vol 13, Iss 9, p 981 (2023)
Treatment of bipolar disorder is prone to prolongation despite various treatments, including medication. The efficacy of exercise treatment (i.e., interventions involving physical exercise and sports intervention) for major depressive disorders has b
Externí odkaz:
https://doaj.org/article/dbfe5c40b2504291b3dc8de07d9d3d1a
Autor:
Hiroko Sugawara, Miki Bundo, Takaoki Kasahara, Yutaka Nakachi, Junko Ueda, Mie Kubota-Sakashita, Kazuya Iwamoto, Tadafumi Kato
Publikováno v:
Molecular Brain, Vol 15, Iss 1, Pp 1-4 (2022)
Abstract Bipolar disorder (BD) is a severe psychiatric disorder characterized by repeated conflicting manic and depressive states. In addition to genetic factors, complex gene–environment interactions, which alter the epigenetic status in the brain
Externí odkaz:
https://doaj.org/article/4e2ce5a08b574a38a809ce8dfba5f286
Autor:
Tempei Ikegame, Yosuke Hidaka, Yutaka Nakachi, Yui Murata, Risa Watanabe, Hiroko Sugawara, Tatsuro Asai, Emi Kiyota, Takeo Saito, Masashi Ikeda, Tsukasa Sasaki, Mamoru Hashimoto, Tomohisa Ishikawa, Minoru Takebayashi, Nakao Iwata, Chihiro Kakiuchi, Tadafumi Kato, Kiyoto Kasai, Miki Bundo, Kazuya Iwamoto
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-7 (2021)
Abstract SLC6A4, which encodes the serotonin transporter, has a functional polymorphism called the serotonin transporter-linked polymorphic region (5-HTTLPR). The 5-HTTLPR consists of short (S) and long (L) alleles, each of which has 14 or 16 tandem
Externí odkaz:
https://doaj.org/article/17b9c7fc185445e79c6e9a586755ede8
Publikováno v:
Annals of General Psychiatry, Vol 20, Iss 1, Pp 1-4 (2021)
Abstract Background Catatonia is a psychomotor syndrome that presents various symptoms ranging from stupor to agitation, with prominent disturbances of volition. Its pathogenesis is poorly understood. Benzodiazepines and electroconvulsive therapy (EC
Externí odkaz:
https://doaj.org/article/b0110303c37f4bf09364708649e646e2
Autor:
Sho Ochiai, Hiroko Sugawara, Yusuke Kajio, Hibiki Tanaka, Tomohisa Ishikawa, Ryuji Fukuhara, Tadashi Jono, Mamoru Hashimoto
Publikováno v:
Annals of General Psychiatry, Vol 18, Iss 1, Pp 1-3 (2019)
Abstract Background Dementia with Lewy bodies (DLB) is characterized by fluctuating cognitive impairments, recurrent visual hallucinations, the motor symptoms of parkinsonism and REM sleep behavior disorder. Various neuropsychiatric symptoms includin
Externí odkaz:
https://doaj.org/article/736f72ccace34937b0069dff09bdd20a
Autor:
Tomoko Kajiya, Hiroko Sugawara, Yusuke Kajio, Satoru Morieda, Hibiki Tanaka, Tadashi Jono, Noboru Fujise, Mamoru Hashimoto
Publikováno v:
Annals of General Psychiatry, Vol 16, Iss 1, Pp 1-3 (2017)
Abstract Background Major depressive episodes with psychotic features are more common in bipolar disorder than in major depressive disorder; however, there is little information on the optimal treatment for bipolar depression with psychotic features.
Externí odkaz:
https://doaj.org/article/880654db378f4da08c62893a64995fd0
Autor:
An-a Kazuno, Kenji Ohtawa, Kaori Otsuki, Masaya Usui, Hiroko Sugawara, Yuji Okazaki, Tadafumi Kato
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e53855 (2013)
Bipolar disorder is a severe mental illness characterized by recurrent manic and depressive episodes. In bipolar disorder, family and twin studies suggest contributions from genetic and environmental factors; however, the detailed molecular pathogene
Externí odkaz:
https://doaj.org/article/485dfdc56757435fa7f3ed729ff5c0e0
Autor:
Chih-Chieh Yu, Mari Furukawa, Kazuhiro Kobayashi, Chizuru Shikishima, Pei-Chieng Cha, Jun Sese, Hiroko Sugawara, Kazuya Iwamoto, Tadafumi Kato, Juko Ando, Tatsushi Toda
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e47081 (2012)
Human intelligence, as measured by intelligence quotient (IQ) tests, demonstrates one of the highest heritabilities among human quantitative traits. Nevertheless, studies to identify quantitative trait loci responsible for intelligence face challenge
Externí odkaz:
https://doaj.org/article/db94cf8f23714085899ebbcb8ab8235f